Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ferenc. Hutterer"'
Publikováno v:
Annals of the New York Academy of Sciences. 86:1075-1088
Autor:
J. Roboz, Jack Rudick, Fenton Schaffner, Peter Czygan, Ferenc Hutterer, Helmut Greim, Hans Popper, Trülzsch D
Publikováno v:
Biochemical Medicine. 9:158-166
Human liver microsomes isolated from surgical biopsy specimen hydroxylate taurolithocholic acid in the 6α position. The reaction requires NADPH. The identification of the reaction product as hyodeoxycholic acid is based on data obtained from gas chr
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 750:291-299
A form of cytochrome P-450 which comigrates with cytochrome P-450LM4 (molecular weight, 55 000) on SDS-polyacrylamide gel was purified from liver microsomes of cholestyramine-treated rabbits. This form of cytochrome P-450 catalyzed the 7 alpha-hydrox
Autor:
David Y. Cooper, Helmut Greim, Jack Rudick, Otto Rosenthal, Ferenc Hutterer, Fenton Schaffner, Hans Popper, Peter Czygan, Trülzsch D
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 354:168-171
The conversion of taurolithocholate to taurohyodeoxycholate by 6α-hydroxylation by isolated human liver microsomes and NADPH is inhibited by CO and the inhibition is maximally reversedby monochromatic light at 450 nm indicating that the reaction is
Autor:
Hans Popper, Ferenc Hutterer, Jack Rudick, Helmut Greim, Peter Czygan, Anthony J. Garro, Fenton Schaffner
Publikováno v:
JNCI: Journal of the National Cancer Institute. 51:1761-1764
Cortisone effect in stages of hepatic injury. A cytochemical, autoradiographic, and histologic study
Publikováno v:
Experimental and Molecular Pathology. 1:85-95
The effects of cortisone treatment in different stages of liver injury were studied using subacute ethionine intoxication in the rat as experimental model. The progression of the disease was divided into a “florid” phase during which bile ductula
Autor:
Ferenc Hutterer, Paolo G. Bacchin, John B. Schenkman, Helmut Denk, Fenton Schaffner, Hans Popper
Publikováno v:
Experimental and Molecular Pathology. 14:263-276
Synthetic nonionic and anionic detergents interact with the cytochrome P-450 dependent microsomal biotransformation system in three somewhat overlapping stages depending on dose and time of exposure. In the first stage, the detergents bind to P-450,
Autor:
Fenton Schaffner, John B. Schenkman, Hans Popper, Paolo G. Bacchin, Helmut Denk, Ferenc Hutterer
Publikováno v:
Life Sciences. 9:1159-1166
1. 1. Dihydroxy bile acids, which give a Type I binding spectrum with cytochrome P-450, increase the initial rate of P-450 reductase in concentration below 1.0 mM. 2. 2. At 1.0 mM they dissociate the flavoprotein P-450 reductase from P-450, resulting
Autor:
Helmut Denk, Hans Popper, Fenton Schaffner, Ferenc Hutterer, Paolo G. Bacchin, Laszlo Sarkozi, H. Herbert Scharnbeck
Publikováno v:
Gastroenterology. 60:888-897
To determine whether changes in the function of the hepatocellular microsomal biotransformation system play a role in the genesis of cholestasis or result from it, the biochemical alterations in the biotransformation system and the appearance of the
Autor:
Trülzsch D, Fenton Schaffner, Jack Rudick, Hans Popper, Ferenc Hutterer, Peter Czygan, Helmut Greim
Publikováno v:
Gastroenterology. 63:846-850
The bile acid pattern was determined in 12 surgical biopsy specimens, and in four necropsy specimens of human liver. In normal livers, cholic acid is usually the predominant one. Only traces of lithocholic acid were found. In severe biliary obstructi