Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ferenc Tömösi"'
Autor:
Bernadett Tuka, Tamás Körtési, Nikolett Nánási, Ferenc Tömösi, Tamás Janáky, Dániel Veréb, Délia Szok, János Tajti, László Vécsei
Publikováno v:
The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background The glutamatergic neurotransmission has important role in the pathomechanism of primary headache disorders. The kynurenine metabolites derived from catabolism of tryptophan (Trp) have significant involvement not only in glutamater
Externí odkaz:
https://doaj.org/article/98904679be004e20b1d831426f210864
Autor:
Bernadett Tuka, Aliz Nyári, Edina Katalin Cseh, Tamás Körtési, Dániel Veréb, Ferenc Tömösi, Gábor Kecskeméti, Tamás Janáky, János Tajti, László Vécsei
Publikováno v:
The Journal of Headache and Pain, Vol 22, Iss 1, Pp 1-19 (2021)
Abstract Background Altered glutamatergic neurotransmission and neuropeptide levels play a central role in migraine pathomechanism. Previously, we confirmed that kynurenic acid, an endogenous glutamatergic antagonist, was able to decrease the express
Externí odkaz:
https://doaj.org/article/507659b064f9467ea027987656c38642
Autor:
Péter Traj, Ali Hazhmat Abdolkhaliq, Anett Németh, Sámuel Trisztán Dajcs, Ferenc Tömösi, Tea Lanisnik-Rizner, István Zupkó, Erzsébet Mernyák
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 895-902 (2021)
Facile syntheses of 3-O-carbamoyl, -sulfamoyl, or -pivaloyl derivatives of 13α-oestrone and its 17-deoxy counterpart have been carried out. Microwave-induced, Ni-catalysed Suzuki–Miyaura couplings of the newly synthesised phenol esters with phenyl
Externí odkaz:
https://doaj.org/article/8ac3570ea79d474fb73fbcddc31a94e6
Autor:
Sándor Váczi, Lilla Barna, Krisztián Laczi, Ferenc Tömösi, Gábor Rákhely, Botond Penke, Lívia Fülöp, Ferenc Bogár, Tamás Janáky, Mária A Deli, Zsófia Mezei
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0265854 (2022)
BackgroundDiabetes mellitus is a chronic metabolic disorder which induces endothelial dysfunction and platelet activation. Eicosanoids produced from arachidonic acid regulate cellular and vascular functions. Sigma-1 receptors (S1R) are expressed in p
Externí odkaz:
https://doaj.org/article/45361d039b8b4702905ac32b2e0dc908
Autor:
Dezső P. Virok, Ferenc Tömösi, Anikó Keller-Pintér, Kitti Szabó, Anita Bogdanov, Szilárd Poliska, Zsolt Rázga, Bella Bruszel, Zsuzsanna Cseh, Dávid Kókai, Dóra Paróczai, Valéria Endrész, Tamás Janáky, Katalin Burián
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
AimsNeutrophil granulocytes are the major cells involved in Chlamydia trachomatis (C. trachomatis)-mediated inflammation and histopathology. A key protein in human intracellular antichlamydial defense is the tryptophan-degrading enzyme indoleamine 2,
Externí odkaz:
https://doaj.org/article/34085d989e0e45c2aac7cd1d4117ce0c
Autor:
Rita Ambrus, Péter Gieszinger, Róbert Gáspár, Anita Sztojkov-Ivanov, Eszter Ducza, Árpád Márki, Tamás Janáky, Ferenc Tömösi, Gábor Kecskeméti, Piroska Szabó-Révész, Csilla Bartos
Publikováno v:
Molecules, Vol 25, Iss 5, p 1065 (2020)
Nasal drug delivery has become a popular research field in the last years. This is not surprising since the nose possesses unique anatomical and physical properties. Via the nasal mucosa local, systemic, and directly central nerve systemic (CNS) effe
Externí odkaz:
https://doaj.org/article/21f9c8452f514ba0a5567f39fc6f3f11
Autor:
Gábor Katona, György Tibor Balogh, Gergő Dargó, Róbert Gáspár, Árpád Márki, Eszter Ducza, Anita Sztojkov-Ivanov, Ferenc Tömösi, Gábor Kecskeméti, Tamás Janáky, Tamás Kiss, Rita Ambrus, Edina Pallagi, Piroska Szabó-Révész, Ildikó Csóka
Publikováno v:
Pharmaceutics, Vol 12, Iss 2, p 97 (2020)
The aim of this study was to optimize the formulation of meloxicam (MEL)-containing human serum albumin (HSA) nanoparticles for nose-to-brain via a quality by design (QbD) approach. Liquid and dried formulations of nanoparticles containing Tween 80 a
Externí odkaz:
https://doaj.org/article/77354d97f84547919f76ee4e1cd7e1c5
Autor:
Csilla Bartos, Rita Ambrus, Anita Kovács, Róbert Gáspár, Anita Sztojkov-Ivanov, Árpád Márki, Tamás Janáky, Ferenc Tömösi, Gábor Kecskeméti, Piroska Szabó-Révész
Publikováno v:
Molecules, Vol 23, Iss 4, p 784 (2018)
The aim of this article was to study the trans-epithelial absorption to reach the blood and to target the brain by axonal transport using nasal formulations with nanonized meloxicam (nano MEL spray) and its salt form known as meloxicam potassium mono
Externí odkaz:
https://doaj.org/article/bf9200aca0b945e2acd063f7c038ad76
Autor:
Aniko Keller-Pinter, Ferenc Tömösi, Zsuzsanna Cseh, Dezső P. Virok, Kitti Szabo, Dávid Kókai, Tamás Janáky, Szilárd Póliska, Katalin Burián, Anita Bogdanov, Valéria Endrész, Bella Bruszel, Dóra Paróczai, Zsolt Rázga
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
AimsNeutrophil granulocytes are the major cells involved in Chlamydia trachomatis (C. trachomatis)-mediated inflammation and histopathology. A key protein in human intracellular antichlamydial defense is the tryptophan-degrading enzyme indoleamine 2,
Autor:
Gabor Kecskemeti, József Toldi, Péter Klivényi, Ferenc Rárosi, Ferenc Tömösi, László Vécsei, László Sztriha, Ádám Annus, Tamás Janáky, Evelin Fehér
Publikováno v:
Advances in clinical and experimental medicine : official organ Wroclaw Medical University. 30(12)
Background Biomarkers for predicting treatment response to thrombolysis in acute ischemic stroke are currently lacking. Both, animal models and clinical studies have provided evidence that the kynurenine (KYN) pathway is activated in ischemic stroke.