Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ferenc Szekeres"'
Autor:
Heléne Lindholm, Matthew Herring, Maria Faresjö, Johan Haux, Ferenc Szekeres, Katarina Ejeskär
Publikováno v:
International Journal of Translational Medicine, Vol 4, Iss 2, Pp 224-237 (2024)
The NLRP3 inflammasome is an important mediator of the host inflammatory response, and downregulation of inflammation is important in cancer treatment. Here, we investigated four different pancreatic ductal adenocarcinoma (PDAC) cell lines, AsPC-1, B
Externí odkaz:
https://doaj.org/article/75ff956dd79240d48c27c19d9d6ce075
Publikováno v:
International journal of molecular sciences. 23(15)
Digitoxin has repeatedly shown to have negative effects on cancer cell viability; however, the actual mechanism is still unknown. In this study, we investigated the effects of digitoxin (1-100 nM) in four pancreatic cancer cell lines, BxPC-3, CFPAC-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed6120264ab1516f453626ee3c5f9a4b
https://pubmed.ncbi.nlm.nih.gov/35897809
https://pubmed.ncbi.nlm.nih.gov/35897809
The alpha subunits (ATP1A1-3) of Na+/K+-ATPase binds digitoxin with varying affinity. The expression levels of these subunits dictate the anticancer effects of digitoxin. In the present study, three pancreatic cancer cell lines, AsPC-1, Panc-1 and CF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7fb4a361e7a11a7d68ff397c1fa59e
http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-22471
http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-22471
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
The NADPH oxidase enzymes Nox2 and 4, are important generators of Reactive oxygen species (ROS). These enzymes are abundantly expressed in cardiomyocytes and have been implicated in ischemia–reperfusion injury. Previous attempts with full inhibitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8b44b8411edf452b28b2f0eae8c08a
http://europepmc.org/articles/PMC8184855
http://europepmc.org/articles/PMC8184855
Autor:
Sandra Karlsson, Maria Araceli Diaz Cruz, Maria Faresjö, Ferenc Szekeres, Dennis Larsson, Dan Lund
Publikováno v:
Molecular Biology Reports
Prostate cancer (PCa) is a highly heterogeneous and unpredictable progressive disease. Sensitivity of PCa cells to androgens play a central role in tumor aggressiveness but biomarkers with high sensitivity and specificity that follow the progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef33a8d304428b58a0fb67ee3ca8a09c
http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-19611
http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-19611
Autor:
Ferenc Szekeres, Dan Lund, Maria Faresjö, Sandra Karlsson, Maria Araceli Diaz Cruz, Dennis Larsson
Publikováno v:
Open Medicine
Open Medicine, Vol 16, Iss 1, Pp 640-650 (2021)
Open Medicine, Vol 16, Iss 1, Pp 640-650 (2021)
Nuclear receptors (NRs) are ligand-activated transcription factors that regulate gene expression when bound to specific DNA sequences. Crosstalk between steroid NR systems has been studied for understanding the development of hormone-driven cancers b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56220a2d58090f19897c7c1b06e706e
http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-19687
http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-19687
Autor:
Maria Araceli Diaz Cruz, Sandra Karlsson, Ferenc Szekeres, Maria Faresjö, Dan Lund, Johan Haux, Dennis Larsson
The authors have withdrawn this preprint due to author disagreement.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e2c3913069d9825cc3ef7b7f6ce7f6c
https://doi.org/10.21203/rs.2.17515/v3
https://doi.org/10.21203/rs.2.17515/v3
Publikováno v:
Pflugers Archiv
This study aims to improve the classification of smooth muscle types to better understand their normal and pathological functional phenotypes. Four different smooth muscle tissues (aorta, muscular arteries, intestine, urinary bladder) with a 5-fold d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d65973a719bc6c7f873d333fa3044e4
https://doi.org/10.1007/s00424-017-2096-6
https://doi.org/10.1007/s00424-017-2096-6
Autor:
Maria Araceli Diaz Cruz, Pontus Karlsson, Gustav Högberg, Sandra Karlsson, Ferenc Szekeres, Dan Lund, Johan Haux, Dennis Larsson
Background Prostate cancer (PC) is a heterogeneous and unpredictable disease and becomes untreatable when the tumor progress to castrate-resistant (CR) or androgen independent (AI). A major clinical challenge in prostate cancer is the lack of diagnos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6077d444ffa937673a2024fd9a44088
https://doi.org/10.21203/rs.2.17515/v1
https://doi.org/10.21203/rs.2.17515/v1
Autor:
William M Hanes, Sangeeta S. Chavan, Betty Diamond, Nichol E. Holodick, Anders Arner, Andrea Introini, Ferenc Szekeres, Roozbeh Sobbi, Michaela Oswald, Thomas L. Rothstein, Cecilia Lövdahl, Shu Fang Liu, Edmund J. Miller, Huan Yang, Valentin A. Pavlov, Benjamin E. Steinberg, Tak W. Mak, Peter K. Gregersen, Ulf Andersson, Kristina Broliden, Peter H. Backx, Kevin J. Tracey, Peder S. Olofsson, Maureen A. Cox, Mohamed Ahmed
Publikováno v:
Nature Biotechnology. 34:1066-1071
Blood pressure regulation is known to be maintained by a neuro-endocrine circuit, but whether immune cells contribute to blood pressure homeostasis has not been determined. We previously showed that CD4+ T lymphocytes that express choline acetyltrans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55935650517e1792b6b194e2a59f3606
https://doi.org/10.1038/nbt.3663
https://doi.org/10.1038/nbt.3663