Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ferenc Otvös"'
Publikováno v:
BMC Chemistry, Vol 17, Iss 1, Pp 1-12 (2023)
Abstract Like most phosphinic acids, the potent and selective RXP03 inhibitor of different MMPs exhibited moderate absorption and low bioavailability, which impaired its use. In an unprecedented attempt, we present an interesting synthetic approach t
Externí odkaz:
https://doaj.org/article/b42718a024154463859bb30a779d0d4a
Autor:
Ferenc Ötvös, Edina Szűcs, Ákos Urai, István Köteles, Pál T. Szabó, Zsuzsanna Katalin Varga, Dávid Gombos, Sándor Hosztafi, Sándor Benyhe
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Opiate alkaloids and their synthetic derivatives are still widely used in pain management, drug addiction, and abuse. To avoid serious side effects, compounds with properly designed pharmacological profiles at the opioid receptor subtypes ar
Externí odkaz:
https://doaj.org/article/b5b57eb3746046f899b96dbae84ce431
Publikováno v:
Life, Vol 13, Iss 12, p 2288 (2023)
We previously reported on a novel peptaibol, named Tripleurin XIIc (TPN), an 18-residue long sequence produced by the fungus Trichoderma pleuroti. We elucidated its 3D structure via classical and accelerated molecular dynamics simulation (aMD) method
Externí odkaz:
https://doaj.org/article/aaaa9bcf0f8e4535a4b82c10411cf2b2
Autor:
Alexandra Bocsik, Ilona Gróf, Lóránd Kiss, Ferenc Ötvös, Ottó Zsíros, Lejla Daruka, Lívia Fülöp, Monika Vastag, Ágnes Kittel, Norbert Imre, Tamás A. Martinek, Csaba Pál, Piroska Szabó-Révész, Mária A. Deli
Publikováno v:
Pharmaceutics, Vol 11, Iss 2, p 73 (2019)
The absorption of drugs is limited by the epithelial barriers of the gastrointestinal tract. One of the strategies to improve drug delivery is the modulation of barrier function by the targeted opening of epithelial tight junctions. In our previous s
Externí odkaz:
https://doaj.org/article/ad596b738be64d58ad3f57efe307d65a
Autor:
Zoltán Oláh, Katalin Jósvay, László Pecze, Tamás Letoha, Norbert Babai, Dénes Budai, Ferenc Otvös, Sándor Szalma, Csaba Vizler
Publikováno v:
PLoS ONE, Vol 2, Iss 6, p e545 (2007)
Ca(2+)-loaded calmodulin normally inhibits multiple Ca(2+)-channels upon dangerous elevation of intracellular Ca(2+) and protects cells from Ca(2+)-cytotoxicity, so blocking of calmodulin should theoretically lead to uncontrolled elevation of intrace
Externí odkaz:
https://doaj.org/article/f77ba262583840ebbceb6a0d8cd0e666
Publikováno v:
Molecules, Vol 24, Iss 2, p 358 (2019)
Peptaibols are a special class of fungal peptides with an acetylated N-terminus and a C-terminal 1,2-amino alcohol along with non-standard amino acid residues. New peptaibols named tripleurins were recently identified from a strain of the filamentous
Externí odkaz:
https://doaj.org/article/befb73c8c369469ab72e850735cff652