Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ferenc Makra"'
Autor:
Cheng-I. Mau, Andreas Jekle, Ferenc Makra, Surya Sankuratri, Paul Weller, André deRosier, Eun Kyung Lee, Gabriel Stephen Deems, Gabrielle Heilek, David Mark Rotstein, Changhua Ji, Shelley K. Gleason, Christine E. Brotherton-Pleiss, Marianna Dioszegi, Lubov Filonova, Lina Setti, Pamela Berry, Alejandra Trejo-Martin
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:5401-5406
A novel series of CCR5 antagonists has been identified, utilizing leads from high-throughput screening which were further modified based on insights from competitor molecules. Lead optimization was pursued by balancing opposing trends of metabolic st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a12820458536333a16236817f9aa665
https://doi.org/10.1016/j.bmcl.2009.07.122
https://doi.org/10.1016/j.bmcl.2009.07.122
Autor:
Xiaochun Han, Yun-Chou Tan, Sue Jin, Paul J. Wagner, Alejandra Trejo, Parch Tivitmahaisoon, David Mark Rotstein, Bindu Goyal, Andreas Kuglstatter, Wylie Solang Palmer, Leyi Gong, Brian Wong, Patricia Tran, Alam Jahagir, Alice Chang, Joseph Dal Porto, Linghao Niu, Johaness Hermann, Fengrong Zuo, James Patrick Dunn, Karin Ann Stein, Heather Hogg, Muzaffar Alam, Ada Shao, David Michael Goldstein, Deborah Carol Reuter, Ferenc Makra, Gary Hsieh, Brad Loe, Lubov Filonova, Lubica Rapatova, Tania Silva
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(12)
A novel series of indole/indazole-aminopyrimidines was designed and synthesized with an aim to achieve optimal potency and selectivity for the c-Jun kinase family or JNKs. Structure guided design was used to optimize the series resulting in a signifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1d571f35d6a4f78286cd06b8fa7d5d
https://pubmed.ncbi.nlm.nih.gov/23664880
https://pubmed.ncbi.nlm.nih.gov/23664880
Publikováno v:
ChemInform. 27
Potassium enolates derived from readily available o-alkynylacetophenones undergo intramolecular cycloaromatization on heating to afford 3-alkyl-1-naphthols in good yields.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b558febe331018fb99eed6e3d692697c
https://doi.org/10.1002/chin.199601114
https://doi.org/10.1002/chin.199601114