Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ferenc Csizmadia"'
Autor:
Ferenc Csizmadia, Miklós Vargyas, György Pirok, Nóra Máté, Jozsef Szegezdi, Jeno Varga, Szilárd Dóránt
Publikováno v:
Journal of Chemical Information and Modeling. 46:563-568
Predicting "realistic" compounds of given chemical reactions with virtual synthesis tools usually requires the manual intervention of experienced chemists in the enumeration phase for the selection of appropriate reactants, assignment of the correspo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595480a9250c1ece21c83e6de502418b
https://doi.org/10.1021/ci050373p
https://doi.org/10.1021/ci050373p
Publikováno v:
Scopus-Elsevier
The efficiency of the program PrologD to predict distribution coefficients (D) at any pH and pairing ion concentration has been tested using experimental logD values for various drugs measured under standard conditions of buffers and ionic strength.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525b9bea8aae3e6531609d928a0c1645
https://doi.org/10.1007/bf03190022
https://doi.org/10.1007/bf03190022
Autor:
Laszlo Endrenyi, Ferenc Csizmadia
Publikováno v:
Journal of Pharmaceutical Sciences. 87:608-612
The effectiveness of five model-independent procedures for the estimation of lag times (Tlag) was evaluated. Two new methods utilize early concentrations which are weighted by a term exponential in time. They estimate Tlag by weighted linear regressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537324d9f480199056d561397f8d86e4
https://doi.org/10.1021/js9703333
https://doi.org/10.1021/js9703333
Publikováno v:
Pharmaceutical Research. 15:1292-1299
Purpose. To compare the effectiveness of various metrics which evaluate bioequivalence in the early phase of concentration-time profiles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c6e6ef39ceb410dc7371458d2bc94bd
https://doi.org/10.1023/a:1011912512966
https://doi.org/10.1023/a:1011912512966
Publikováno v:
Pharmaceutical Research. 15:399-404
Purpose. To determine favourable sampling conditions for assessing bioequivalence by the comparison of partial AUCs in the early phase of concentration-time profiles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b52796fe25eddd00a0c108e2a0adb11
https://doi.org/10.1023/a:1011916113082
https://doi.org/10.1023/a:1011916113082
Publikováno v:
Journal of Pharmaceutical Sciences. 86:865-871
A method has been developed for the estimation of the distribution coefficient (D), which considers the microspecies of a compound. D is calculated from the microscopic dissociation constants (microconstants), the partition coefficients of the micros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f5c90b812df71413ecf319ee02ac728
https://doi.org/10.1021/js960177k
https://doi.org/10.1021/js960177k
Publikováno v:
Journal of Chromatography A. 660:33-46
Several approaches can be used for the prediction of the optimum eluent composition in RP-HPLC, but only a few are known that use the structure of the solute. The latest release of the computer program EluEx, version 3.0, was developed to help the ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::694fff3facc9d2bb584b500e4414e19f
https://doi.org/10.1016/0021-9673(94)85097-6
https://doi.org/10.1016/0021-9673(94)85097-6
Publikováno v:
Proceedings of The 8th International Electronic Conference on Synthetic Organic Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88cfd17b341eccc9689b77c638217693
https://doi.org/10.3390/ecsoc-8-01969
https://doi.org/10.3390/ecsoc-8-01969
Autor:
Ferenc Csizmadia
Publikováno v:
Journal of chemical information and computer sciences. 40(2)
A Java based development tool for building portable chemical information systems is presented. The system contains applets for constructing web-based interfaces and classes that add structure handling to relational databases. Custom applications buil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4be494d8c31ae9bfceb4ec2ccbac107
https://pubmed.ncbi.nlm.nih.gov/10761134
https://pubmed.ncbi.nlm.nih.gov/10761134
Publikováno v:
Journal of pharmaceutical sciences. 86(10)
Prolog D is a program that formalizes, in a controllable and reproducible manner, an algorithm developed to predict distribution coefficients of ionizable compounds at a given pH and varying counterion concentrations. Its predictive power has been ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ce3fdfad04dd75ccaa28955f469146
https://pubmed.ncbi.nlm.nih.gov/9344176
https://pubmed.ncbi.nlm.nih.gov/9344176