Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Ferenc Bogár"'
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0289467 (2023)
The adhesion of biomolecules to dental and orthopedic implants is a fundamental step in the process of osseointegration. Short peptide motifs, such as RGD or KRSR, carried by extracellular matrix proteins or coated onto implant surfaces, accelerate c
Externí odkaz:
https://doaj.org/article/38925de883404d9083654ba9b76c4bc9
Autor:
Attila Tököli, Brigitta Bodnár, Ferenc Bogár, Gábor Paragi, Anasztázia Hetényi, Éva Bartus, Edit Wéber, Zsófia Hegedüs, Zoltán Szabó, Gábor Kecskeméti, Gerda Szakonyi, Tamás A. Martinek
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1032 (2023)
Single-stranded DNA-binding protein (SSB) is a bacterial interaction hub and an appealing target for antimicrobial therapy. Understanding the structural adaptation of the disordered SSB C-terminus (SSB-Ct) to DNA metabolizing enzymes (e.g., ExoI and
Externí odkaz:
https://doaj.org/article/171a5d32aa4d46fab92fec3fbf67804e
Autor:
Sándor Váczi, Lilla Barna, Krisztián Laczi, Ferenc Tömösi, Gábor Rákhely, Botond Penke, Lívia Fülöp, Ferenc Bogár, Tamás Janáky, Mária A Deli, Zsófia Mezei
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0265854 (2022)
BackgroundDiabetes mellitus is a chronic metabolic disorder which induces endothelial dysfunction and platelet activation. Eicosanoids produced from arachidonic acid regulate cellular and vascular functions. Sigma-1 receptors (S1R) are expressed in p
Externí odkaz:
https://doaj.org/article/45361d039b8b4702905ac32b2e0dc908
Publikováno v:
Biomolecules, Vol 12, Iss 3, p 363 (2022)
Neurodegenerative diseases (NDDs) are characterized by progressive deterioration of the structure and function of cells and their networks in the nervous system. There are currently no drugs or other treatments that can stop the progression of NDDs.
Externí odkaz:
https://doaj.org/article/7eda3336cf514c068d53c74ed25d1cc2
Publikováno v:
Molecules, Vol 25, Iss 7, p 1659 (2020)
The structural polymorphism and the physiological and pathophysiological roles of two important proteins, β-amyloid (Aβ) and tau, that play a key role in Alzheimer’s disease (AD) are reviewed. Recent results demonstrate that monomeric Aβ has imp
Externí odkaz:
https://doaj.org/article/dbcbec8815f94eefb21f89c6014b3e7c
Publikováno v:
Molecules, Vol 22, Iss 10, p 1692 (2017)
Protein dyshomeostasis is the common mechanism of neurodegenerative diseases such as Alzheimer’s disease (AD). Aging is the key risk factor, as the capacity of the proteostasis network declines during aging. Different cellular stress conditions res
Externí odkaz:
https://doaj.org/article/276b99a0faf64bb5b3aaccb0875ae507
Autor:
Imre Bogár, György Dévai, Martina Gyöngy, László Szabó, Sándor Nagy, Imre Somlyai, Ferenc Bogár, Csaba Berta, István Grigorszky, György Varga, Lucza Zoltán
Publikováno v:
Landscape & Environment. 15:16-32
One of the main threats of our time is the increasing water demand not only globally, but also locally. These are often met at the expense of ecological water demand, jeopardizing the structural and operational conditions necessary to maintain good e
Publikováno v:
International Journal of Molecular Sciences. 24:5383
Alzheimer’s disease (AD) is an incurable, progressive neurodegenerative disorder. AD is a complex and multifactorial disease that is responsible for 60–80% of dementia cases. Aging, genetic factors, and epigenetic changes are the main risk factor
Autor:
Sándor Váczi, Lilla Barna, Krisztián Laczi, Ferenc Tömösi, Gábor Rákhely, Botond Penke, Lívia Fülöp, Ferenc Bogár, Tamás Janáky, Mária A. Deli, Zsófia Mezei
Publikováno v:
European journal of pharmacology. 925
Platelets regulate cell-cell interactions and local circulation through eicosanoids from arachidonic acid. Sigma non-opioid intracellular receptor 1 (sigma-1 receptor) expressed in platelets and endothelial cells can regulate intracellular signalizat
Autor:
Zita Zalán, Ferenc Bogár, Ferenc Fülöp, Lívia Fülöp, Csaba Tömböly, László Lázár, Botond Penke, Márta Palkó, Szabolcs Dvorácskó
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8112, p 8112 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences
Volume 22
Issue 15
Sigma-1 receptor (S1R) is an intracellular, multi-functional, ligand operated protein that also acts as a chaperone. It is considered as a pluripotent drug target in several pathologies. The publication of agonist and antagonist bound receptor struct