Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ferdynand Kos"'
Autor:
Mihaela Cristea, Don J. Diamond, Joshua D.I. Ellenhorn, Sharon Wilczynski, Melissa Eng, Raechelle Tinsley, Vincent Chung, Robert Morgan, Lucille Leong, Teodora Kaltcheva, Ferdynand Kos, Weimin Tsai, Julie Kilpatrick, Christopher Ruel, Paul Frankel, Nicola R. Hardwick
Purpose: To conduct a phase I trial of a Modified Vaccinia Ankara vaccine delivering wild-type human p53 (p53MVA) in combination with gemcitabine chemotherapy in patients with platinum-resistant ovarian cancer.Experimental Design: Patients received g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d4b175596cb5843fe4fc2cddd99043
https://doi.org/10.1158/1078-0432.c.6524738
https://doi.org/10.1158/1078-0432.c.6524738
Autor:
Mihaela Cristea, Don J. Diamond, Joshua D.I. Ellenhorn, Sharon Wilczynski, Melissa Eng, Raechelle Tinsley, Vincent Chung, Robert Morgan, Lucille Leong, Teodora Kaltcheva, Ferdynand Kos, Weimin Tsai, Julie Kilpatrick, Christopher Ruel, Paul Frankel, Nicola R. Hardwick
Figure S1: Frequency of Tregs does not significantly decline post treatment and does not correlate with p53-reactivity or PFS.; Figure S2: Frequency of MDSC does not significantly differ to healthy controls, does not decline post treatment and does n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc76b5ba272b15288966e2ad53ec19a5
https://doi.org/10.1158/1078-0432.22461248
https://doi.org/10.1158/1078-0432.22461248
Publikováno v:
Cancer Immunology, Immunotherapy. 65:869-874
Adoptive cell therapy (ACT) employing ex vivo generated tumor-antigen specific CD8+ T cells shows tumor efficacy when the transferred cells possess both effector and memory functions. New strategies based on understanding of mechanisms that balance C
Autor:
Don J. Diamond, Joshua D. I. Ellenhorn, Mihaela C. Cristea, Lucille Leong, Julie Kilpatrick, Raechelle Tinsley, Sharon P. Wilczynski, Melissa Eng, Christopher Ruel, Nicola Hardwick, Ferdynand Kos, Robert J. Morgan, Weimin Tsai, Vincent Chung, Paul Frankel, Teodora Kaltcheva
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 24(6)
Purpose: To conduct a phase I trial of a Modified Vaccinia Ankara vaccine delivering wild-type human p53 (p53MVA) in combination with gemcitabine chemotherapy in patients with platinum-resistant ovarian cancer. Experimental Design: Patients received
Autor:
Christopher J. Thoburn, Leo Luznik, Christopher D. Gocke, Janet Briel, B. Douglas Smith, Christian F. Meyer, Christopher G. Kanakry, Judith E. Karp, Ferdynand Kos, Allan D. Hess, Hyam I. Levitsky
Publikováno v:
Blood. 117:608-617
Few published studies characterize early lymphocyte recovery after intensive chemotherapy for acute myelogenous leukemia (AML). To test the hypothesis that lymphocyte recovery mirrors ontogeny, we characterized early lymphocyte recovery in 20 consecu
Publikováno v:
Cancer Immunology, Immunotherapy. 59:799-803
Essentially all squamous cervical cancers and their precursor lesions, high grade cervical intraepithelial neoplasia (CIN2/3), are caused by persistent human papil-lomavirus (HPV) infection. However, not all CIN2/3 lesions progress to cancer. In a br
Autor:
Patti E. Gravitt, Cornelia L. Trimble, Elizabeth A. Sugar, Shiwen Peng, Drew M. Pardoll, Tzyy Choou Wu, Ferdynand Kos, Raphael P. Viscidi
Publikováno v:
Clinical Cancer Research. 15:361-367
Purpose: To evaluate the safety and immunogenicity of a therapeutic human papillomavirus (HPV)16 DNA vaccine administered to women with HPV16+cervical intraepithelial neoplasia (CIN)2/3. Experimental Design: This phase I trial incorporated the standa
Autor:
Jean Glenn, Jack R. Bennink, Valerie Pasquetto, David C. Tscharke, Howard M. Grey, Ferdynand Kos, Huynh Hoa Bui, Tara N. Palmore, Scott Southwood, Alessandro Sette, Carla Oseroff, John Sidney, Bjoern Peters, Jonathan W. Yewdell
Publikováno v:
Proceedings of the National Academy of Sciences. 102:13980-13985
We have analyzed byex vivoELISPOT the anti-vaccinia cytotoxic T lymphocyte responses of peripheral blood mononuclear cells from humans vaccinated with Dryvax vaccine. More than 6,000 peptides from 258 putative vaccinia ORFs predicted to bind the comm
Autor:
Suzanne L. Topalian, John Sidney, Alessandro Sette, A. Michelle English, Tracee L. McMiller, Ferdynand Kos, Yili Li, Roy A. Mariuzza, Steven A. Rosenberg, Shuming Chen, Florence R. Depontieu, Jeffrey Shabanowitz, Donald F. Hunt
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 191(10)
Insights gained from characterizing MHC–peptide–TCR interactions have held the promise that directed structural modifications can have predictable functional consequences. The ability to manipulate T cell reactivity synthetically or through genet
Publikováno v:
Cancer Diagnostics ISBN: 9781617373992
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a099375c03076c97febaa53777a62a1
https://doi.org/10.1007/978-1-59259-791-8_10
https://doi.org/10.1007/978-1-59259-791-8_10