Systematic review and meta-analysis of cannabinoids, cannabis-based medicines, and endocannabinoid system modulators tested for antinociceptive effects in animal models of injury-related or pathological persistent pain.

Autor: Soliman N; Pain Research, Department of Surgery and Cancer, Imperial College London, London, United Kingdom., Haroutounian S; Department of Anesthesiology, Washington University Pain Center, Washington University School of Medicine, St. Louis, Missouri, United States., Hohmann AG; Department of Psychological and Brain Sciences, Program in Neuroscience and Gill Center for Biomolecular Science, Bloomington, IN, United States., Krane E; Departments of Anesthesiology, Perioperative, and Pain Medicine, & Pediatrics, Stanford University School of Medicine, Stanford, CA, United States., Liao J; CAMARADES, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom., Macleod M; CAMARADES, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom., Segelcke D; Department of Anesthesiology, Intensive Care and Pain Medicine University Hospital Muenster, Muenster, Germany., Sena C; CAMARADES, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom., Thomas J; EPPI-Centre, University College London, London, United Kingdom., Vollert J; Pain Research, Department of Surgery and Cancer, Imperial College London, London, United Kingdom., Wever K; SYRCLE at Central Animal Laboratory, Radbound University Medical Center, Nijmegen, the Netherlands., Alaverdyan H; Department of Anesthesiology, Washington University Pain Center, Washington University School of Medicine, St. Louis, Missouri, United States., Barakat A; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Assiut University, Asyut, Egypt., Barthlow T; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bozer ALH; Department of Psychological Sciences, Tarleton State University, Stephenville, TX, United States., Davidson A; Countess of Chester Hospital, Chester, United Kingdom., Diaz-delCastillo M; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Dolgorukova A; Valdman Institute of Pharmacology, Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Russia., Ferdousi MI; Pharmacology and Therapeutics, School of Medicine, Galway Neuroscience Centre and Centre for Pain Research, Human Biology Building, National University of Ireland Galway, Galway, Ireland., Healy C; Pharmacology and Therapeutics, School of Medicine, Galway Neuroscience Centre and Centre for Pain Research, Human Biology Building, National University of Ireland Galway, Galway, Ireland., Hong S; Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, United States., Hopkins M; Pharmacology and Therapeutics, School of Medicine, Galway Neuroscience Centre and Centre for Pain Research, Human Biology Building, National University of Ireland Galway, Galway, Ireland., James A; Leicester General Hospital, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom., Leake HB; IIMPACT in Health, University of South Australia, Adelaide, South Australia, Australia.; Centre for Pain IMPACT, Neuroscience Research Australia, Sydney, New South Wales, Australia., Malewicz NM; Department of Anaesthesiology, Intensive Care Medicine and Pain Management, Medical Faculty of Ruhr-University Bochum, BG University Hospital Bergmannsheil gGmbH, Bochum, Germany., Mansfield M; Department of Allied Health Sciences, Institute of Health and Social Care, Pain Research Cluster, Ageing, Acute and Long Term Conditions Research Group, London South Bank University, London, United Kingdom., Mardon AK; IIMPACT in Health, University of South Australia, Adelaide, South Australia, Australia., Mattimoe D; Pharmacology and Therapeutics, School of Medicine, Galway Neuroscience Centre and Centre for Pain Research, Human Biology Building, National University of Ireland Galway, Galway, Ireland., McLoone DP; Pharmacology and Therapeutics, School of Medicine, Galway Neuroscience Centre and Centre for Pain Research, Human Biology Building, National University of Ireland Galway, Galway, Ireland., Noes-Holt G; Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Pogatzki-Zahn EM; Department of Anesthesiology, Intensive Care and Pain Medicine University Hospital Muenster, Muenster, Germany., Power E; Pharmacology and Therapeutics, School of Medicine, Galway Neuroscience Centre and Centre for Pain Research, Human Biology Building, National University of Ireland Galway, Galway, Ireland., Pradier B; Department of Anesthesiology, Intensive Care and Pain Medicine University Hospital Muenster, Muenster, Germany., Romanos-Sirakis E; Staten Island University Hospital Northwell Health, Staten Island, NY, United States.; Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States., Segelcke A; Independent Researcher., Vinagre R; Visiting Scholar, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA, United States., Yanes JA; Department of Psychological Sciences, Auburn University, Auburn, AL, United States., Zhang J; King's College London GKT School of Medical Education, King's College London, London, United Kingdom., Zhang XY; Pain Research, Department of Surgery and Cancer, Imperial College London, London, United Kingdom., Finn DP; Pharmacology and Therapeutics, School of Medicine, Galway Neuroscience Centre and Centre for Pain Research, Human Biology Building, National University of Ireland Galway, Galway, Ireland., Rice ASC; Pain Research, Department of Surgery and Cancer, Imperial College London, London, United Kingdom.

Publikováno v: Pain [Pain] 2021 Jul 01; Vol. 162 (Suppl 1), pp. S26-S44.

Hyporesponsivity to mu-opioid receptor agonism in the Wistar-Kyoto rat model of altered nociceptive responding associated with negative affective state.

Autor: Ferdousi MI; Pharmacology and Therapeutics, School of Medicine, National University of Ireland Galway, Galway, Ireland.; Physiology, School of Medicine, National University of Ireland Galway, Galway, Ireland., Calcagno P; Pharmacology and Therapeutics, School of Medicine, National University of Ireland Galway, Galway, Ireland.; Centre for Pain Research and Galway Neuroscience Centre, National University of Ireland Galway, Galway, Ireland.; Physiology, School of Medicine, National University of Ireland Galway, Galway, Ireland., Clarke M; Pharmacology and Therapeutics, School of Medicine, National University of Ireland Galway, Galway, Ireland.; Centre for Pain Research and Galway Neuroscience Centre, National University of Ireland Galway, Galway, Ireland.; Physiology, School of Medicine, National University of Ireland Galway, Galway, Ireland., Aggarwal S; Pharmacology and Therapeutics, School of Medicine, National University of Ireland Galway, Galway, Ireland.; Centre for Pain Research and Galway Neuroscience Centre, National University of Ireland Galway, Galway, Ireland.; Physiology, School of Medicine, National University of Ireland Galway, Galway, Ireland., Sanchez C; Alkermes Inc, Waltham, MA, United States., Smith KL; Alkermes Inc, Waltham, MA, United States., Eyerman DJ; Alkermes Inc, Waltham, MA, United States., Kelly JP; Pharmacology and Therapeutics, School of Medicine, National University of Ireland Galway, Galway, Ireland.; Physiology, School of Medicine, National University of Ireland Galway, Galway, Ireland., Roche M; Centre for Pain Research and Galway Neuroscience Centre, National University of Ireland Galway, Galway, Ireland.; Physiology, School of Medicine, National University of Ireland Galway, Galway, Ireland., Finn DP; Pharmacology and Therapeutics, School of Medicine, National University of Ireland Galway, Galway, Ireland.; Physiology, School of Medicine, National University of Ireland Galway, Galway, Ireland.

Publikováno v: Pain [Pain] 2021 Feb 01; Vol. 162 (2), pp. 405-420.