Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Ferdinando Pucci"'
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Three main areas of research revolve around extracellular vesicles (EVs): their use as early detection diagnostics for cancer prevention, engineering of EVs or other enveloped viral-like particles for therapeutic purposes and to understand how EVs im
Externí odkaz:
https://doaj.org/article/b3e8cfa18af043cbae1cc33bd99a9a1a
Autor:
Patricia Gonzalez-Callejo, Zihan Guo, Tahereh Ziglari, Natalie Marcia Claudio, Kayla Hoang Nguyen, Naoki Oshimori, Joaquim Seras-Franzoso, Ferdinando Pucci
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0279400 (2023)
Immunotherapy is an approved treatment option for head and neck squamous cell carcinoma (HNSCC). However, the response rate to immune checkpoint blockade is only 13% for recurrent HNSCC, highlighting the urgent need to better understand tumor-immune
Externí odkaz:
https://doaj.org/article/b2f7cfabc2bb4823b8bbd4ee93bda77b
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Lymph nodes are key lymphoid organs collecting lymph fluid and migratory cells from the tissue area they survey. When cancerous cells arise within a tissue, the sentinel lymph node is the first immunological organ to mount an immune response. Sub-cap
Externí odkaz:
https://doaj.org/article/31eaaf388924471b98b16fbea5a41ebf
Autor:
Filippo Cortesi, Gloria Delfanti, Andrea Grilli, Arianna Calcinotto, Francesca Gorini, Ferdinando Pucci, Roberta Lucianò, Matteo Grioni, Alessandra Recchia, Fabio Benigni, Alberto Briganti, Andrea Salonia, Michele De Palma, Silvio Bicciato, Claudio Doglioni, Matteo Bellone, Giulia Casorati, Paolo Dellabona
Publikováno v:
Cell Reports, Vol 22, Iss 11, Pp 3006-3020 (2018)
Summary: Heterotypic cellular and molecular interactions in the tumor microenvironment (TME) control cancer progression. Here, we show that CD1d-restricted invariant natural killer (iNKT) cells control prostate cancer (PCa) progression by sculpting t
Externí odkaz:
https://doaj.org/article/faebda8f523a42ab810086cf1148a6f8
Autor:
Ferdinando Pucci, Steffen Rickelt, Andita P. Newton, Christopher Garris, Ernesto Nunes, Charles Evavold, Christina Pfirschke, Camilla Engblom, Mari Mino-Kenudson, Richard O. Hynes, Ralph Weissleder, Mikael J. Pittet
Publikováno v:
Cell Reports, Vol 17, Iss 7, Pp 1764-1772 (2016)
Co-option of host components by solid tumors facilitates cancer progression and can occur in both local tumor microenvironments and remote locations. At present, the signals involved in long-distance communication remain insufficiently understood. He
Externí odkaz:
https://doaj.org/article/aa982c8c23874ad09beb98265cad7e03
Autor:
Alexander Hamm, Lorenzo Veschini, Yukiji Takeda, Sandra Costa, Estelle Delamarre, Mario Leonardo Squadrito, Anne‐Theres Henze, Mathias Wenes, Jens Serneels, Ferdinando Pucci, Carmen Roncal, Andrey Anisimov, Kari Alitalo, Michele De Palma, Massimiliano Mazzone
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 6, Pp 843-857 (2013)
Abstract Occlusion of the main arterial route redirects blood flow to the collateral circulation. We previously reported that macrophages genetically modified to express low levels of prolyl hydroxylase domain protein 2 (PHD2) display an arteriogenic
Externí odkaz:
https://doaj.org/article/8f6bfb11625640c6b6a746efcd094543
Autor:
Mario Leonardo Squadrito, Ferdinando Pucci, Laura Magri, Davide Moi, Gregor D. Gilfillan, Anna Ranghetti, Andrea Casazza, Massimiliano Mazzone, Robert Lyle, Luigi Naldini, Michele De Palma
Publikováno v:
Cell Reports, Vol 1, Iss 2, Pp 141-154 (2012)
Expression of the mannose receptor (MRC1/CD206) identifies macrophage subtypes, such as alternatively activated macrophages (AAMs) and M2-polarized tumor-associated macrophages (TAMs), which are endowed with tissue-remodeling, proangiogenic, and prot
Externí odkaz:
https://doaj.org/article/7b15bca799014178ae7195ee22b1ec25
Autor:
Jeffrey T. Gu, Mathew Geltzeiler, Courtney Betts, Natalie Claudio, Ferdinando Pucci, Shamilene Sivagnanam
Publikováno v:
Int Forum Allergy Rhinol
BACKGROUND: Treatment and prognosis of sinonasal squamous cell carcinoma (SNSCC) have not significantly improved despite improvements in radical therapy. Characterization of the tumor immune microenvironment (TiME) may identify patient subgroups asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f01724c041a8b023b0750adcdd736b5
https://doi.org/10.1002/alr.22867
https://doi.org/10.1002/alr.22867
Autor:
Ferdinando Pucci, Lisa M. Coussens
Publikováno v:
Cancer Cell
Tumor-associated macrophages (TAMs) promote metastasis and inhibit T cells, yet macrophages can be polarized to kill cancer cells. Macrophage polarization could thus be a strategy for controlling cancer. We show that macrophages from metastatic pleur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4901d9e1548a4dfdbddf2260a281ee02
https://pubmed.ncbi.nlm.nih.gov/34478639
https://pubmed.ncbi.nlm.nih.gov/34478639
Lymph nodes are key lymphoid organs collecting lymph fluid and migratory cells from the tissue area they survey. When cancerous cells arise within a tissue, the sentinel lymph node is arguably the first immunological organ to mount an immune response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38f9e5855c22b279954745c488c076d2
https://doi.org/10.1101/2021.01.14.425337
https://doi.org/10.1101/2021.01.14.425337
