Zobrazeno 1 - 10
of 966
pro vyhledávání: '"Ferdinando, Nicoletti"'
Autor:
Serena Notartomaso, Nico Antenucci, Mariacristina Mazzitelli, Xavier Rovira, Serena Boccella, Flavia Ricciardi, Francesca Liberatore, Xavier Gomez-Santacana, Tiziana Imbriglio, Milena Cannella, Charleine Zussy, Livio Luongo, Sabatino Maione, Cyril Goudet, Giuseppe Battaglia, Amadeu Llebaria, Ferdinando Nicoletti, Volker Neugebauer
Publikováno v:
eLife, Vol 13 (2024)
We used light-sensitive drugs to identify the brain region-specific role of mGlu5 metabotropic glutamate receptors in the control of pain. Optical activation of systemic JF-NP-26, a caged, normally inactive, negative allosteric modulator (NAM) of mGl
Externí odkaz:
https://doaj.org/article/7992b22d74894ac98d325b25e79626e5
Autor:
Nico Antenucci, Giovanna D’Errico, Francesco Fazio, Ferdinando Nicoletti, Valeria Bruno, Giuseppe Battaglia
Publikováno v:
Schizophrenia, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract Alterations in the kynurenine pathway of tryptophan metabolism have been implicated in the pathophysiology of schizophrenia. Here, we performed an in-depth analysis of all metabolites of the kynurenine pathway, i.e., tryptophan (TRY), kynure
Externí odkaz:
https://doaj.org/article/7ace12d11ab04073974eecd0d05f27f4
Autor:
Katia Mangano, Aristidis Diamantopoulos, Natalia G. Vallianou, Theodora Stratigou, Fotis Panagopoulos, Dimitris Kounatidis, Maria Dalamaga, Paolo Fagone, Ferdinando Nicoletti
Publikováno v:
Metabolism Open, Vol 24, Iss , Pp 100320- (2024)
Background: Macrophage migration inhibitory factor (MIF) is a highly conserved cytokine with pleiotropic properties, mainly pro-inflammatory. MIF seems to exert its pro-inflammatory features by binding to its transmembrane cellular receptor CD74. MIF
Externí odkaz:
https://doaj.org/article/f0e12ffd3eb3411684d25498797dd470
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Externí odkaz:
https://doaj.org/article/65dbfa139f3f47da8bd072e51ab112cd
Autor:
Diletta Camussi, Valentina Naef, Letizia Brogi, Stefania Della Vecchia, Maria Marchese, Ferdinando Nicoletti, Filippo M. Santorelli, Rosario Licitra
Publikováno v:
Cells, Vol 13, Iss 16, p 1349 (2024)
Autism spectrum disorder (ASD) is a multifactorial neurodevelopmental condition with several identified risk factors, both genetic and non-genetic. Among these, prenatal exposure to valproic acid (VPA) has been extensively associated with the develop
Externí odkaz:
https://doaj.org/article/1f8fcdb91acb417b94843ef2adf14899
Publikováno v:
Cells, Vol 13, Iss 15, p 1299 (2024)
Triple-negative breast cancer (TNBC) represents an aggressive subtype of breast cancer, with a bad prognosis and lack of targeted therapeutic options. Characterized by the absence of estrogen receptors, progesterone receptors, and HER2 expression, TN
Externí odkaz:
https://doaj.org/article/8a8adf4173254f3c919ed938e3ba9f6c
Autor:
Carla Letizia Busceti, Domenico Bucci, Massimiliano De Lucia, Michela Ferrucci, Mariarosaria Scioli, Albino Carrizzo, Ferdinando Nicoletti, Carmine Vecchione, Francesco Fornai
Publikováno v:
Life, Vol 14, Iss 6, p 723 (2024)
Methamphetamine (METH) exposure increases locomotor sensitization. However, no study has explored the occurrence of cardiovascular sensitization. The present study, carried out in mice, analyzed the following: (i) METH sensitization extending to syst
Externí odkaz:
https://doaj.org/article/1e66fe4ad9ee4425bfadeced37b8a3ea
Autor:
Paolo Fagone, Katia Mangano, Maria Sofia Basile, José Francisco Munoz-Valle, Vincenzo Perciavalle, Ferdinando Nicoletti, Klaus Bendtzen
Publikováno v:
Genes, Vol 15, Iss 5, p 634 (2024)
In the present study, we have explored the involvement of Toll-like Receptor 4 (TLR4) in atrial fibrillation (AF), by using a meta-analysis of publicly available human transcriptomic data. The meta-analysis revealed 565 upregulated and 267 downregula
Externí odkaz:
https://doaj.org/article/a917f574daaa43a5a550ea3cf8e65913
Autor:
Francisco Javier Turrubiates-Hernández, Samuel García-Arellano, Laura Elena Herrera-Jiménez, Guillermo González-Estevez, Fabiola Márquez-Sandoval, Diana Lourdes Padilla-Bórquez, Hazael Ramiro Ceja-Gálvez, Natali Vega-Magaña, Ferdinando Nicoletti, Guillermina Muñoz-Ríos, José Francisco Muñoz-Valle
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 6, p 1538 (2024)
Background: Respiratory tract infections remain among the leading causes of mortality worldwide. The COVID-19 pandemic has highlighted the importance of mucosal immunity in defending against infectious agents. Vitamin A is known to influence the prod
Externí odkaz:
https://doaj.org/article/a7b4a566878c4ea28cb1ec5646f58927
Autor:
Sara Morley-Fletcher, Alessandra Gaetano, Vance Gao, Eleonora Gatta, Gilles Van Camp, Hammou Bouwalerh, Pierre Thomas, Ferdinando Nicoletti, Stefania Maccari
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 3014 (2024)
The rat model of perinatal stress (PRS), in which exposure of pregnant dams to restraint stress reduces maternal behavior, is characterized by a metabolic profile that is reminiscent of the “metabolic syndrome”. We aimed to identify plasma metabo
Externí odkaz:
https://doaj.org/article/d1790b8c2ab34160918328ec9d7df9a7