Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Ferdinando, Fiorino"'
Autor:
Giorgia Andreozzi, Angela Corvino, Beatrice Severino, Elisa Magli, Elisa Perissutti, Francesco Frecentese, Vincenzo Santagada, Giuseppe Caliendo, Ferdinando Fiorino
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1320 (2024)
Background: In recent decades, there has been a startling rise in the number of cancer patients worldwide, which has led to an amazing upsurge in the development of novel anticancer treatment candidates. On a positive note, arylpiperazines have garne
Externí odkaz:
https://doaj.org/article/04bd4eff63af4682b323a7288afe23a7
Autor:
José Britto-Júnior, Rafael Furlaneto, Antonio Tiago Lima, Mariana Gonçalves de Oliveira, Beatrice Severino, Francesco Frecentese, Ferdinando Fiorino, Giuseppe Caliendo, Marcelo Nicolás Muscará, Gilberto De Nucci
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: The human umbilical artery (HUA), rat-isolated right atrium, and rat-isolated vas deferens present a basal release of 6-nitrodopamine (6-ND). The basal release of 6-ND from these tissues was significantly decreased (but not abolished) w
Externí odkaz:
https://doaj.org/article/2f38f458f02f4026a5a5f710af3f2c29
Autor:
Angela Corvino, Elisabetta Granato, Antonia Scognamiglio, Ferdinando Fiorino, Francesco Frecentese, Elisa Magli, Elisa Perissutti, Vincenzo Santagada, Giuseppe Cirino, Ida Cerqua, Rocco Pavese, Antonio Petti, Francesca Pavese, Francesco Petti, Fiorentina Roviezzo, Beatrice Severino, Giuseppe Caliendo
Publikováno v:
Molecules, Vol 29, Iss 18, p 4514 (2024)
In this study, a new and straightforward process for the preparation of budesonide 21-phosphate (Bud-21P) and its disodium salt (Bud-21P-Na2) is described. The method results in a yield comparable to those obtained by diphosphoryl chloride, but it is
Externí odkaz:
https://doaj.org/article/a3abcecee4cf44e68dc1c62fe07cd798
Autor:
Rosa Sparaco, Pierfrancesco Cinque, Antonia Scognamiglio, Angela Corvino, Giuseppe Caliendo, Ferdinando Fiorino, Elisa Magli, Elisa Perissutti, Vincenzo Santagada, Beatrice Severino, Paolo Luciano, Marcello Casertano, Anna Aiello, Gustavo Yuri Martins Viegas, Gilberto De Nucci, Francesco Frecentese
Publikováno v:
Molecules, Vol 29, Iss 7, p 1598 (2024)
4-Nitro and 7-nitro propranolol have been recently synthesized and characterized by us. (±)-4-NO2-propranolol has been shown to act as a selective antagonist of 6-nitrodopamine (6-ND) receptors in the right atrium of rats. As part of our follow-up t
Externí odkaz:
https://doaj.org/article/1faca57576ae452e9550a466612b7446
Autor:
Giorgia Andreozzi, Maria Rosaria Ambrosio, Elisa Magli, Giovanni Maneli, Beatrice Severino, Angela Corvino, Rosa Sparaco, Elisa Perissutti, Francesco Frecentese, Vincenzo Santagada, Anna Leśniak, Magdalena Bujalska-Zadrożny, Giuseppe Caliendo, Pietro Formisano, Ferdinando Fiorino
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1483 (2023)
Arylpiperazines represent one of the most important classes of 5-HT1AR ligands and have attracted considerable interests for their versatile properties in chemistry and pharmacology, leading to the research of new derivatives that has been focused on
Externí odkaz:
https://doaj.org/article/f809eadae0904facb28d7ccc4163c291
Autor:
Maria Rosaria Ambrosio, Elisa Magli, Giuseppe Caliendo, Rosa Sparaco, Paola Massarelli, Vittoria D’Esposito, Teresa Migliaccio, Giusy Mosca, Ferdinando Fiorino, Pietro Formisano
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Serotonin (or 5-Hydroxytryptamine, 5-HT) signals in mammary gland becomes dysregulated in cancer, also contributing to proliferation, metastasis, and angiogenesis. Thus, the discovery of novel compounds targeting serotonin signali
Externí odkaz:
https://doaj.org/article/1ff550da64d74d238fdea77957c3ed5d
Autor:
Angela Corvino, Valentina Citi, Ferdinando Fiorino, Francesco Frecentese, Elisa Magli, Elisa Perissutti, Vincenzo Santagada, Vincenzo Calderone, Alma Martelli, Era Gorica, Simone Brogi, Flavia Faganello Colombo, Caroline Nunes Capello, Heloisa Helena Araujo Ferreira, Maria Grazia Rimoli, Federica Sodano, Barbara Rolando, Francesca Pavese, Antonio Petti, Marcelo Nicolás Muscará, Giuseppe Caliendo, Beatrice Severino
Publikováno v:
Journal of Advanced Research, Vol 35, Iss , Pp 267-277 (2022)
Introduction: Hydrogen sulfide (H2S) is a fundamental biological endogenous gas-mediator in the respiratory system. It regulates pivotal patho-physiological processes such as oxidative stress, pulmonary circulation, airway tone and inflammation. Obje
Externí odkaz:
https://doaj.org/article/610e9a0c8bd745389a68efd1fc4472d6
Autor:
Valentina Citi, Angela Corvino, Ferdinando Fiorino, Francesco Frecentese, Elisa Magli, Elisa Perissutti, Vincenzo Santagada, Simone Brogi, Lorenzo Flori, Era Gorica, Lara Testai, Alma Martelli, Vincenzo Calderone, Giuseppe Caliendo, Beatrice Severino
Publikováno v:
Journal of Advanced Research, Vol 27, Iss , Pp 41-53 (2021)
Introduction: The gasotransmitter hydrogen sulphide (H2S), an endogenous ubiquitous signalling molecule, is known for its beneficial effects on different mammalian systems. H2S exhibits cardioprotective activity against ischemia/reperfusion (I/R) or
Externí odkaz:
https://doaj.org/article/8fc49f98c59742828951e1c1870ef95a
Autor:
Vidya Narayanaswami, Junchao Tong, Ferdinando Fiorino, Beatrice Severino, Rosa Sparaco, Elisa Magli, Flavia Giordano, Peter M. Bloomfield, Jaya Prabhakaran, J. John Mann, Neil Vasdev, Kenneth Dahl, J. S. Dileep Kumar
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-17 (2020)
Abstract Background Serotonin 1A (5-HT1A) receptors are implicated in the pathogenesis of several psychiatric and neurodegenerative disorders motivating the development of suitable radiotracers for in vivo positron emission tomography (PET) neuroimag
Externí odkaz:
https://doaj.org/article/d04212c45a1c477c855f4b83967b0456
Autor:
Rosa Sparaco, Antonia Scognamiglio, Angela Corvino, Giuseppe Caliendo, Ferdinando Fiorino, Elisa Magli, Elisa Perissutti, Vincenzo Santagada, Beatrice Severino, Paolo Luciano, Marcello Casertano, Anna Aiello, Gilberto De Nucci, Francesco Frecentese
Publikováno v:
Molecules, Vol 28, Iss 1, p 57 (2022)
We recently identified 6-nitrodopamine and other nitro-catecholamines (6-nitrodopa, 6-nitroadrenaline), indicating that the endothelium has the ability to nitrate the classical catecholamines (dopamine, noradrenaline, and adrenaline). In order to inv
Externí odkaz:
https://doaj.org/article/3ac93dbbe8a24c28ab6152444f9fa139