Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ferdinand Steinboeck"'
Publikováno v:
Data in Brief, Vol 9, Iss C, Pp 1113-1117 (2016)
Research on the mechanisms of adaptive mutagenesis in resting, i.e. non-replicating cells relies on appropriate mutation assays. Here we provide a novel procedure for the detection of frameshift-reverting mutations in yeast. Proliferation of non-reve
Externí odkaz:
https://doaj.org/article/0aa8a68b5a884f188bae194fe515a16b
Publikováno v:
Journal of Microbiological Methods. 132:4-8
Mutations not only arise in proliferating cells but also in resting - thus non-replicating - cells. Such stationary-phase mutations may occasionally enable an escape from growth repression and e.g. contribute to cancerogenesis or development of drug
Publikováno v:
Data in Brief
Data in Brief, Vol 9, Iss C, Pp 1113-1117 (2016)
Data in Brief, Vol 9, Iss C, Pp 1113-1117 (2016)
Research on the mechanisms of adaptive mutagenesis in resting, i.e. non-replicating cells relies on appropriate mutation assays. Here we provide a novel procedure for the detection of frameshift-reverting mutations in yeast. Proliferation of non-reve
Autor:
Marta Weindlmayr, Lukas Weigl, Andrea Michalek-Sauberer, Ferdinand Steinboeck, Birgit Kraft, Alexius Kaufmann, Hans G. Kress
Publikováno v:
Anesthesia & Analgesia. 114:1017-1025
Malignant hyperthermia (MH) is a potentially lethal genetic disorder in response to volatile anesthetics and depolarizing muscle relaxants. To support the claim that a novel genetic variant causes MH, it is necessary to demonstrate that it has signif
Autor:
Petra Dorninger, Ferdinand Steinboeck, Erich Heidenreich, Theresia Lengheimer, Maria Hubmann, Alexandra Bogusch
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 688:47-52
Mutations arising during times of cell cycle-arrest may considerably contribute to aging and cancerogenesis. Endogenous oxidative stress could be one of the major triggers for these mutations. We used Saccharomyces cerevisiae cells, arrested by starv
Autor:
Ferdinand Steinboeck, Theresia Lengheimer, Herfried Eisler, Petra Dorninger, Erich Heidenreich
Publikováno v:
DNA Repair. 9:96-100
Growing attention is paid to the concept that mutations arising in stationary, non-proliferating cell populations considerably contribute to evolution, aging, and pathogenesis. If such mutations are beneficial to the affected cell, in the sense of al
Autor:
Doris Kristufek, Ferdinand Steinboeck
Publikováno v:
Cellular and Molecular Neurobiology. 25:1151-1169
Plectin, a large (500 kDa) dumbbell-shaped cytolinker protein plays an important role in the organization of the cytoskeletal network and the maintenance of cell integrity in a wide variety of tissues and cell types. Earlier experiments revealed the
Publikováno v:
Journal of biochemistry. 141(5)
Ten actin-related proteins are known in Saccharomyces cerevisiae, classified into Arps1-10 according to their relatedness to actin. Arp4, a nuclear protein, essential for viability of S. cerevisiae, is a component of at least three chromatin-modifyin
Autor:
Alexius Kaufmann, Erich Heidenreich, Alexandra Bogusch, Ludmila Krupanska, Ferdinand Steinboeck
Publikováno v:
Journal of biochemistry. 139(4)
ARP4, an essential gene of Saccharomyces cerevisiae, codes for a nuclear actin-related protein. Arp4 is a subunit of several chromatin-modifying complexes and is known to be involved in the transcriptional regulation in yeast. We used a mutant strain
Publikováno v:
Mutation research. 593(1-2)
Mutations arising in times of cell cycle arrest may provide a selective advantage for unicellular organisms adapting to environmental changes. For multicellular organisms, however, they may pose a serious threat, in that such mutations in somatic cel