Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ferdinand Stückler"'
Autor:
Kerstin Matejka, Ferdinand Stückler, Michael Salomon, Regina Ensenauer, Eva Reischl, Lena Hoerburger, Harald Grallert, Gabi Kastenmüller, Annette Peters, Hannelore Daniel, Jan Krumsiek, Fabian J Theis, Hans Hauner, Helmut Laumen
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216110 (2019)
BACKGROUND:Genome-wide association studies of common diseases or metabolite quantitative traits often identify common variants of small effect size, which may contribute to phenotypes by modulation of gene expression. Thus, there is growing demand fo
Externí odkaz:
https://doaj.org/article/113961d0a1f447ac8c8137725c986c27
Autor:
Thomas Michler, Stefanie Große, Stefan Mockenhaupt, Natalie Röder, Ferdinand Stückler, Bettina Knapp, Chunkyu Ko, Mathias Heikenwalder, Ulrike Protzer, Dirk Grimm
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 9, Pp 1082-1098 (2016)
Abstract Hepatitis B virus (HBV) is a promising target for therapies based on RNA interference (RNAi) since it replicates via RNA transcripts that are vulnerable to RNAi silencing. Clinical translation of RNAi technology, however, requires improvemen
Externí odkaz:
https://doaj.org/article/cc0d7efac0984a2bb0526ab75c1cabdd
Autor:
Matthias Griese, Hannah G Kirmeier, Gerhard Liebisch, Daniela Rauch, Ferdinand Stückler, Gerd Schmitz, Ralf Zarbock, ILD-BAL working group of the Kids-Lung-Register
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117985 (2015)
Lipids account for the majority of pulmonary surfactant, which is essential for normal breathing. We asked if interstitial lung diseases (ILD) in children may disrupt alveolar surfactant and give clues for disease categorization.Comprehensive lipidom
Externí odkaz:
https://doaj.org/article/969f5da7d70d473b80d56575fc1ef403
Autor:
Christopher Williams, Susanne Konrad, Jan Griesbach, Jessica Yang, Katharina Doninger, Till Briskot, Moritz Bennecke, Jürgen Hubbuch, Felix Wittkopp, Ferdinand Stückler, Stefan Hepbildikler
Publikováno v:
Journal of Chromatography A. 1587:101-110
Mechanistic modeling of chromatography has been around in academia for decades and has gained increased support in pharmaceutical companies in recent years. Despite the large number of published successful applications, process development in the pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bddbe854c0a82efab44bc39d16570792
https://doi.org/10.1016/j.chroma.2018.11.076
https://doi.org/10.1016/j.chroma.2018.11.076
Autor:
Christian Gieger, Fabian J. Theis, Matthias Nauck, Thomas Illig, Jan Krumsiek, Florian Kronenberg, Jerzy Adamski, Kieu Trinh Do, Nele Friedrich, Annette Peters, Dennis O. Mook-Kanamori, Ferdinand Stückler, Karsten Suhre, Kirstin Mittelstrass, Maik Pietzner, Harald Grallert, Janina S. Ried, Gabi Kastenmüller
Publikováno v:
Metabolomics 11, 1815-1833 (2015)
Metabolomics
Metabolomics
The susceptibility for various diseases as well as the response to treatments differ considerably between men and women. As a basis for a gender-specific personalized healthcare, an extensive characterization of the molecular differences between the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b23643ef6ec96f14e262061febcc6cb
https://doi.org/10.1007/s11306-015-0829-0
https://doi.org/10.1007/s11306-015-0829-0
Autor:
Ferdinand Stückler, Andreas Beyerlein, Daniela Much, Werner Römisch-Margl, Jerzy Adamski, Sandra Hummel, Cornelia Prehn, Alida S.D. Kindt, Gabi Kastenmüller, Anna Hofelich, Michaela Rossbauer, Susanne Hivner, David Wiesenäcker, Anette-G. Ziegler, Melanie Herbst, Fabian J. Theis, Jan Krumsiek
Publikováno v:
Diabetologia
Lactation for3 months in women with gestational diabetes is associated with a reduced risk of type 2 diabetes that persists for up to 15 years postpartum. However, the underlying mechanisms are unknown. We examined whether in women with gestational d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8e06909090b5c9c08ab91dbbe58fd4
https://pubmed.ncbi.nlm.nih.gov/27423999
https://pubmed.ncbi.nlm.nih.gov/27423999
Autor:
Ferdinand Stückler, C Gieger, Karsten Suhre, Kastenmüller G, Nicole Soranzo, Tim D. Spector, Fabian J. Theis, Jan Krumsiek
Genome-wide association studies (GWAS) with metabolite ratios as quantitative traits have successfully deepened our understanding of the complex relationship between genetic variants and metabolic phenotypes. Usually all ratio combinations are select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab843ade9347c47948dc888b737c39a
https://doi.org/10.1101/048512
https://doi.org/10.1101/048512
Autor:
Ferdinand Stückler, Thomas Skurk, Hannelore Daniel, Gabi Kastenmüller, Karsten Suhre, Fabian J. Theis, Cornelia Prehn, Hans Hauner, Werner Römisch-Margl, Jan Krumsiek, Karl-Heinz Engel, Werner Kremer, Ralf Zimmermann, Manuela Sailer, Thomas Hofmann, Susanne M. Krug, Wilfried Szymczak, Jerzy Adamski, Burkhard Luy, Johannes Raffler, Franco Moritz, Fritz Huber, Thomas Frank, Philippe Schmitt-Kopplin, Manuela J. Rist, Uwe Oeh
Publikováno v:
The FASEB Journal. 26:2607-2619
Metabolic challenge protocols, such as the oral glucose tolerance test, can uncover early alterations in metabolism preceding chronic diseases. Nevertheless, most metabolomics data accessible today reflect the fasting state. To analyze the dynamics o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53df7eda78462b66a2e2b5ae0a7fc8a
https://doi.org/10.1096/fj.11-198093
https://doi.org/10.1096/fj.11-198093
Autor:
Jan Krumsiek, Michael Roden, Jörg Bartel, Tim Kacprowski, Christa Meisinger, Katharina Schramm, Heiner Boeing, Pasi Soininen, Christian Gieger, Ute Nöthlings, Ferdinand Stückler, Barbara Thorand, Christian Herder, Gabi Kastenmüller, Melanie Waldenberger, Maren Carstensen, Thomas Illig, Wolfgang Rathmann, Jakob Linseisen, Susanne Vogt, Carolin Jourdan, Holger Prokisch, Karsten Suhre, Georg Homuth, Harald Grallert, Antti J. Kangas, Simone Wahl, Mika Ala-Korpela, Annette Peters, Fabian J. Theis
Publikováno v:
BMC medicine, 13: 48
BMC Medicine
BMC Med. 13:48 (2015)
BMC Medicine
BMC Med. 13:48 (2015)
Background Excess body weight is a major risk factor for cardiometabolic diseases. The complex molecular mechanisms of body weight change-induced metabolic perturbations are not fully understood. Specifically, in-depth molecular characterization of l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289a00c42923beaa6b1198ac9088e2c2
https://doi.org/10.1186/s12916-015-0282-y
https://doi.org/10.1186/s12916-015-0282-y
Autor:
Thomas Illig, Konstantin Strauch, Heinz Erich Wichmann, Ferdinand Stückler, Rui Wang-Sattler, Michael Kabesch, Janina S. Ried, Cornelia Prehn, Christian Gieger, Stephan Weidinger, Hans-Ulrich Schulz, Joachim Heinrich, Fabian J. Theis, Jan Krumsiek, Karsten Suhre, Hansjörg Baurecht, Jerzy Adamski, Annette Peters, Elke Rodriguez
Publikováno v:
Allergy 68, 629-636 (2013)
Background Genome-wide association studies (GWAS) have identified many risk loci for asthma, but effect sizes are small, and in most cases, the biological mechanisms are unclear. Targeted metabolite quantification that provides information about a wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b14471d914a3eb44ab0ac3b88524fc6
https://pubmed.ncbi.nlm.nih.gov/23452035
https://pubmed.ncbi.nlm.nih.gov/23452035