Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ferdinand Sedlmayer"'
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Bacterial populations communicate with AI-2 signaling molecules, helping to coordinate biofilm development and other group behaviors. Here the authors design a genetic circuit for mammalian cells that allows them to sense bacterial populations and in
Externí odkaz:
https://doaj.org/article/f5b4f3ce5f3b40af8b18e1f0b070f445
Autor:
Martin Fussenegger, Florian Fuchs, Anne-Kathrin Woischnig, Daniel K. Baeschlin, Ferdinand Sedlmayer, Nina Khanna, Vincent Unterreiner
Publikováno v:
Nucleic Acids Research, 49 (13)
Nucleic Acids Research
Nucleic Acids Research
Antibiotic-resistant pathogens often escape antimicrobial treatment by forming protective biofilms in response to quorum-sensing communication via diffusible autoinducers. Biofilm formation by the nosocomial pathogen methicillin-resistant Staphylococ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d54a4701d75e15c741fd80851e920ba
https://doi.org/10.1093/nar/gkab251
https://doi.org/10.1093/nar/gkab251
Publikováno v:
Nature biomedical engineering. 2(6)
In living organisms, naturally evolved sensors that constantly monitor and process environmental cues trigger corrective actions that enable the organisms to cope with changing conditions. Such natural processes have inspired biologists to construct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28b3aac4917c327f6a538f34b6a9215
https://pubmed.ncbi.nlm.nih.gov/31011195
https://pubmed.ncbi.nlm.nih.gov/31011195
Publikováno v:
Nano Letters, 17 (8)
Current antibiotics gradually lose their efficacy against chronic Pseudomonas aeruginosa infections due to development of increased resistance mediated by biofilm formation, as well as the large arsenal of microbial virulence factors that are coordin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb427ed1ac5e1ab1095820f6d5547fdb
https://hdl.handle.net/20.500.11850/190642
https://hdl.handle.net/20.500.11850/190642
Publikováno v:
Nature Biomedical Engineering. 1
Genetically modified bacteria provide a long-lasting record of intestinal inflammation in mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee89641eb816b7ea2b36613633f24441
https://doi.org/10.1038/s41551-017-0097
https://doi.org/10.1038/s41551-017-0097
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications, 9
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications, 9
Quorum sensing is a promising target for next-generation anti-infectives designed to address evolving bacterial drug resistance. The autoinducer-2 (AI-2) is a key quorum-sensing signal molecule which regulates bacterial group behaviors and is recogni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0429d3ebfc45ce1a92abc563a4d7168d
https://pubmed.ncbi.nlm.nih.gov/29739943
https://pubmed.ncbi.nlm.nih.gov/29739943
Autor:
Volker Morath, Katrin Seyfarth, Arne Skerra, Martin Klingenspor, Sarah Schneider, Martin Schlapschy, Ferdinand Sedlmayer, Florian Bolze
Publikováno v:
Molecular pharmaceutics. 12(5)
Leptin plays a central role in the control of energy homeostasis and appetite and, thus, has attracted attention for therapeutic approaches in spite of its limited pharmacological activity owing to the very short circulation in the body. To improve d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b84d864fbf30d6c1a6ca65c72c729de
https://pubmed.ncbi.nlm.nih.gov/25811325
https://pubmed.ncbi.nlm.nih.gov/25811325
Autor:
Olivier Frey, Jörg Stelling, Marius Müller, Simon Ausländer, Ghislaine Charpin-El Hamri, Ferdinand Sedlmayer, Andreas Hierlemann, David Ausländer, Martin Fussenegger
Publikováno v:
Molecular Cell
All metabolic activities operate within a narrow pH range that is controlled by the CO2-bicarbonate buffering system. We hypothesized that pH could serve as surrogate signal to monitor and respond to the physiological state. By functionally rewiring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f66f03da788bf80e7bd3a3cbc4490bd