Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Ferdinand Lejeune"'
Autor:
Danielle Liénard, Ferdinand Lejeune, Oliver Gugerli, Maurice Matter, Marie Nicod Lalonde, Hanifa Bouzourene, Angelika Bischof Delaloye, Mohamed Allaoua, Ariane Boubaker, Jean-Philippe Cerottini
Publikováno v:
Journal of Nuclear Medicine. 48:1607-1613
In sentinel node (SN) biopsy, an interval SN is defined as a lymph node or group of lymph nodes located between the primary melanoma and an anatomically well-defined lymph node group directly draining the skin. As shown in previous reports, these int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae71444b1e028b00f21b6d97307d7823
https://doi.org/10.2967/jnumed.107.041707
https://doi.org/10.2967/jnumed.107.041707
Autor:
Ferdinand Lejeune, Dirk J. Ruiter, Danielle Lienard, Lia Schalkwijk, Nathalie Renard, P.T.G.A. Nooijen, Robert M.W. de Waal, Alexander A.M.M. Eggermont, Bin B.B.R. Kroon
Publikováno v:
Journal of Pathology, 176, pp. 279-287
Journal of Pathology, 176, 279-287
Journal of Pathology, 176, 279-287
Twenty-nine stage IIIA/B melanoma patients treated by isolated limb perfusion (ILP) with a high dose of recombinant human tumour necrosis factor alpha (rHuTNF alpha), interferon gamma (IFN gamma), and melphalan were histologically documented with emp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb50efc8d68f79114b9e9872f194209a
https://doi.org/10.1002/path.1711760310
https://doi.org/10.1002/path.1711760310
Autor:
Ferdinand Lejeune, Danielle Lienard, Alexander M.M. Eggermont, Nathalie Renard, Rudolf Heimann, Laurence Lespagnard
Publikováno v:
International Journal of Cancer. 57:656-663
Twenty-seven patients treated with high-dose rTNF alpha, IFN gamma and melphalan by isolated limb perfusion were histologically documented. There were 20 cases of melanoma-in-transit metastases and 7 cases of high-grade soft-tissue sarcoma. Biopsies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a50f4fc9eb97abcc65e1db5459c383
https://doi.org/10.1002/ijc.2910570508
https://doi.org/10.1002/ijc.2910570508
Autor:
Georges Huez, Ferdinand Lejeune, Francisco Solano, Véronique Del Marmol, Ghanem Elias Ghanem, Anita Libert, André Sels
Publikováno v:
Journal of Investigative Dermatology. 101:871-874
The aim of the present work was to estimate the effect of intracellular glutathione depletion on melanogenesis in human melanoma cells. We determined tyrosine hydroxylation activity, the rate-limiting step of the pathway, and 14C-melanin formation, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3095ec78876b1316d391b7c9bcfe675d
https://doi.org/10.1111/1523-1747.ep12371709
https://doi.org/10.1111/1523-1747.ep12371709
Autor:
Ferdinand Lejeune, R Morandini, Giuseppe Prota, D. Mascagna, Marco d'Ischia, Giovanna Misuraca, Ghanem Elias Ghanem
Publikováno v:
Melanoma Research. 2:25-32
New tyrosinase-targeted compounds based on structural variants of the prototype unit 4-aminophenol have been synthesized and screened for their potential as antitumour agents against malignant melanoma. Cytotoxicity assays showed that N-4-hydroxyphen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b81622635e9366407f2dd6f95410c0
https://doi.org/10.1097/00008390-199205000-00004
https://doi.org/10.1097/00008390-199205000-00004
Publikováno v:
World Journal of Surgery. 16:234-240
To increase the therapeutic efficacy of recombinant tumor necrosis factor alpha (rTNFα) and reduce the systemic side effects, a protocol was designed using isolation perfusion of the limbs with hyperthermia for in transit metastases of melanoma. A t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e47e66da1bc6346aa8585b721fcd360
https://doi.org/10.1007/bf02071526
https://doi.org/10.1007/bf02071526
Autor:
Ferdinand Lejeune, Stefan Carrel, Dirk J. Ruiter, Jean François Doré, M. Prade, Ph. Rümke, Ulrich R. Kleeberg, Eva B. Bröcker
Publikováno v:
International Journal of Cancer. 48:836-847
In the framework of the European Organisation for Research and Treatment of Cancer (EORTC), the Immunology and Pathology Subgroups of the Malignant Melanoma Cooperative Group undertook a large multicenter monoclonal antibody (MAb) study. Fourteen lab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548d44309d0edd99acdc04bea698c5cc
https://doi.org/10.1002/ijc.2910480609
https://doi.org/10.1002/ijc.2910480609
Autor:
Ferdinand Lejeune, Fadi Abikhalil, Roland Arnould, Ghanem Atassi, Ghanem Elias Ghanem, Michel Hanocq, Jacques Dubois, Anita Libert
Publikováno v:
Alternatives to Laboratory Animals. 18:225-230
The sensitivity and the selectivity of two murine lymphoid cell lines (P388 and P388D1) to five chemotherapeutic drugs were investigated in vitro. The cytotoxicities of melphalan, daunorubicin, hexamethylmelamine (HMM), hydroxymethylpentamethylmelami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f91c5f5aa4983eaa429714fb22f8f528
https://doi.org/10.1177/026119299001800122.1
https://doi.org/10.1177/026119299001800122.1
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 44(9)
Isobutyl and isohexyl cyanoacrylate nanoparticles are used as drug carriers, particularly for some anti-cancer drugs. Body distribution as well as pharmacokinetics have been well studied in animal and partially in man. Labelling of the monomer itself
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f0e60b506565bcc6a160bca62f677b
https://pubmed.ncbi.nlm.nih.gov/8401451
https://pubmed.ncbi.nlm.nih.gov/8401451
Publikováno v:
Seminars in surgical oncology. 8(6)
Disseminated melanoma remains a tumour that is poorly responsive to chemotherapy and radiotherapy. However, this review demonstrates that surgical removal of visceral metastases such as at the, lung or digestive sites, as well as the brain, yields co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9bff2ce90896361fededc67116abc4
https://pubmed.ncbi.nlm.nih.gov/1439449
https://pubmed.ncbi.nlm.nih.gov/1439449