Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ferdinand Kappes"'
Autor:
Mareike Bütepage, Christian Preisinger, Alexander von Kriegsheim, Anja Scheufen, Eva Lausberg, Jinyu Li, Ferdinand Kappes, Regina Feederle, Sabrina Ernst, Laura Eckei, Sarah Krieg, Gerhard Müller-Newen, Giulia Rossetti, Karla L. H. Feijs, Patricia Verheugd, Bernhard Lüscher
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Abstract Macrodomains are conserved protein folds associated with ADP-ribose binding and turnover. ADP-ribosylation is a posttranslational modification catalyzed primarily by ARTD (aka PARP) enzymes in cells. ARTDs transfer either single or multiple
Externí odkaz:
https://doaj.org/article/827b3706279b44c7a5d83f1b4485f73c
Autor:
Metehan Cifdaloz, Lisa Osterloh, Osvaldo Graña, Erica Riveiro-Falkenbach, Pilar Ximénez-Embún, Javier Muñoz, Cristina Tejedo, Tonantzin G. Calvo, Panagiotis Karras, David Olmeda, Belén Miñana, Gonzalo Gómez-López, Estela Cañon, Eduardo Eyras, Haihong Guo, Ferdinand Kappes, Pablo L. Ortiz-Romero, Jose L. Rodríguez-Peralto, Diego Megías, Juan Valcárcel, María S. Soengas
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Hundreds of mRNA binding proteins (mRBPs) have been described in mammalian cells. Here, the authors identify RBPs differentially regulated in melanoma, and show the RBP CELF1 controlling a distinct set of protumorigenic factors.
Externí odkaz:
https://doaj.org/article/1340379aab9748ac8e9ce5a84d0a223c
Autor:
Magdalena Ganz, Christopher Vogel, Christina Czada, Vera Jörke, Eva Christina Gwosch, Rebecca Kleiner, Agnieszka Pierzynska-Mach, Francesca Cella Zanacchi, Alberto Diaspro, Ferdinand Kappes, Alexander Bürkle, Elisa Ferrando-May
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0213130 (2019)
DNA replication stress is a major source of genomic instability and is closely linked to tumor formation and progression. Poly(ADP-ribose)polymerases1/2 (PARP1/2) enzymes are activated in response to replication stress resulting in poly(ADP-ribose) (
Externí odkaz:
https://doaj.org/article/22ac9e7cb3004020837049802bf64386
Autor:
Agnieszka Pierzynska-Mach, Christina Czada, Christopher Vogel, Eva Gwosch, Xenia Osswald, Denis Bartoschek, Alberto Diaspro, Ferdinand Kappes, Elisa Ferrando-May
The correct inheritance of chromatin structure is key for maintaining genome function and preventing cellular transformation. DEK, a conserved chromatin protein, has recognized tumor-promoting properties, its overexpression being associated with poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01362ea808cbdb14d72bdaed25f37355
https://doi.org/10.1101/2023.03.09.529154
https://doi.org/10.1101/2023.03.09.529154
Autor:
Maureen A. Sartor, Rafael Contreras-Galindo, Haihong Guo, Christopher T Lee, David M. Markovitz, Hal E. Broxmeyer, Maureen Legendre, Nirit Mor-Vaknin, Scott Cooper, Xinxin Huang, Maegan L. Capitano, Anjan K. Saha, Ferdinand Kappes
Publikováno v:
Journal of Clinical Investigation. 129:2555-2570
The nuclear protein DEK is an endogenous DNA-binding chromatin factor regulating hematopoiesis. DEK is one of only 2 known secreted nuclear chromatin factors, but whether and how extracellular DEK regulates hematopoiesis is not known. We demonstrated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9723efd9cc213a1afb1d7230def270c
https://doi.org/10.1172/jci127460
https://doi.org/10.1172/jci127460
Autor:
Haihong Guo, Malte Prell, Bernhard Lüscher, Nengwei Xu, Ferdinand Kappes, Hiltrud Königs, Benita Hermanns-Sachweh
Publikováno v:
FEBS lettersReferences. 595(10)
In two proof-of-concept studies, we established and validated the Bacterial Growth Inhibition Screen (BGIS), which explores recombinant protein toxicity in Escherichia coli as a largely overlooked and alternative means for basic characterization of f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96873ed1554cf42ebb4df97fc41b9f30
https://pubmed.ncbi.nlm.nih.gov/33704777
https://pubmed.ncbi.nlm.nih.gov/33704777
Autor:
Benita Hermans-Sachweh, Malte Prell, Bernhard Lüscher, Tanja Waldmann, Haihong Guo, Nengwei Xu, Elisa Ferrando-May, Hiltrud Königs, Ferdinand Kappes
Publikováno v:
FEBS lettersReferences. 595(10)
The DEK oncoprotein regulates cellular chromatin function via a number of protein-protein interactions. However, the biological relevance of its unique pseudo-SAP/SAP-box domain, which transmits DNA modulating activities in vitro, remains largely spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36846dd9d74f141c96bbb0f0c7bf58e
https://pubmed.ncbi.nlm.nih.gov/33686684
https://pubmed.ncbi.nlm.nih.gov/33686684
Autor:
Christopher Vogel, Alexander Bürkle, Vera Jörke, Christina Czada, Agnieszka Pierzynska-Mach, Francesca Cella Zanacchi, Elisa Ferrando-May, Ferdinand Kappes, Alberto Diaspro, Rebecca Kleiner, Magdalena Ganz
DNA replication stress is a major source of genomic instability and is closely linked to tumor formation and progression. Poly(ADP-ribose)polymerases1/2 (PARP1/2) enzymes are activated in response to replication stress resulting in poly(ADP-ribose) (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab77429b2f53ec00a87ddd9335c23960
Autor:
Alexander Bürkle, Rebecca Kleiner, Christina Czada, Elisa Ferrando-May, Vera Jörke, Magdalena Ganz, Francesca Cella Zanacchi, Alberto Diaspro, Eva Gwosch, Ferdinand Kappes, Christopher Vogel, Agnieszka Pierzynska-Mach
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 8, p e0213130 (2019)
PLoS ONE, Vol 14, Iss 8, p e0213130 (2019)
DNA replication stress is a major source of genomic instability and is closely linked to tumor formation and progression. Poly(ADP-ribose)polymerases1/2 (PARP1/2) enzymes are activated in response to replication stress resulting in poly(ADP-ribose) (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42a8c3ea0d34d2b7b8d4f0e48abb7076
https://pubmed.ncbi.nlm.nih.gov/31408463
https://pubmed.ncbi.nlm.nih.gov/31408463
Autor:
Ana Cecília de Albuquerque Oliveira, Danyelly Bruneska Gondim Martins, José Luiz de Lima Filho, Ferdinand Kappes
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 106
Breast and cervical cancer are the first and fourth cancer types with the highest prevalence in women, respectively. The developmental profiles of cancer in women can vary by genetic markers and cellular events. In turn, age and lifestyle influence i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b433b2e1d677486b69d740ebb8200e
https://pubmed.ncbi.nlm.nih.gov/29957464
https://pubmed.ncbi.nlm.nih.gov/29957464