Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ferdinand Kühner"'
Autor:
Robert A. Lugmaier, Hermann E. Gaub, Kerstin Blank, Julia Sedlmair, Julia Morfill, Ferdinand Kühner
Publikováno v:
Biophysical Journal. 93:2400-2409
Stretching experiments with long double-stranded DNA molecules in physiological ambient revealed a force-induced transition at a force of 65pN. During this transition between B-DNA and highly overstretched S-DNA the DNA lengthens by a factor of 1.7 o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b387d1d6f33a31f1afde1598198164a
https://doi.org/10.1529/biophysj.107.106112
https://doi.org/10.1529/biophysj.107.106112
Publikováno v:
European Biophysics Journal. 37:111-120
P-pili of uropathogenic Escherichia coli mediate the attachment to epithelial cells in the human urinary tract and kidney and therefore play an important role in infection. A better understanding of this mechanism could help to prevent bacteria from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0392c688350adc84cf4b009799c9b4
https://doi.org/10.1007/s00249-007-0183-x
https://doi.org/10.1007/s00249-007-0183-x
Autor:
Andreas Serr, Hermann E. Gaub, Ferdinand Kühner, Matthias Erdmann, Lars Sonnenberg, Julia Morfill
Publikováno v:
Langmuir. 22:11180-11186
Atomic force microscope (AFM) single molecule force spectroscopy has been used to investigate the friction coefficient of individual polymers adsorbed onto a solid support. The polymer chains were covalently attached to an AFM tip and were allowed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db1f0fa478f5d33fd5c60ca99f2b30e
https://doi.org/10.1021/la061704a
https://doi.org/10.1021/la061704a
Autor:
Ferdinand Kühner, Hermann E. Gaub
Publikováno v:
Polymer. 47:2555-2563
Polymers play a central role in cantilever-based single molecule force spectroscopy, either as sample or as anchor of the molecular complexes under investigation. Here we investigated the role of the polymer for the coupling of thermal and mechanical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06a914effff95483a4e1ca232cc02151
https://doi.org/10.1016/j.polymer.2005.12.090
https://doi.org/10.1016/j.polymer.2005.12.090
Publikováno v:
Journal of Physics: Condensed Matter. 15:S1709-S1723
Dynamic force spectroscopy is a valuable technique to explore the energy landscape of molecular interactions. Polymer spacers are typically used to couple the binding partners to the surfaces. To illustrate the impact of polymer spacers on the measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30d0b6db1592b30efa4c7bab1fad74d7
https://doi.org/10.1088/0953-8984/15/18/305
https://doi.org/10.1088/0953-8984/15/18/305
Publikováno v:
Journal of the American Chemical Society. 129(47)
DNA displays a richness of biologically relevant supramolecular structures, which depend on both sequence and ambient conditions. The effect of dragging double-stranded DNA (dsDNA) from water into poor solvent on the double-stranded structure is stil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee3ab1ccc9cab5e194044528bb03caca
https://pubmed.ncbi.nlm.nih.gov/17983226
https://pubmed.ncbi.nlm.nih.gov/17983226
Publikováno v:
The Review of scientific instruments. 78(7)
Progress in scanning probe microscopy profited from a flourishing multitude of new instrument designs, which lead to novel imaging modes and as a consequence to innovative microscopes. Often these designs were hampered by the restrictions, which conv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb0d7aac7b55573e0d9d45347c531ce
https://pubmed.ncbi.nlm.nih.gov/22462975
https://pubmed.ncbi.nlm.nih.gov/22462975
Publikováno v:
Langmuir
Langmuir, American Chemical Society, 2007, 23 (12), pp.6660-6666. ⟨10.1021/la063682y⟩
Langmuir, 2007, 23 (12), pp.6660-6666. ⟨10.1021/la063682y⟩
Langmuir, American Chemical Society, 2007, 23 (12), pp.6660-6666. ⟨10.1021/la063682y⟩
Langmuir, 2007, 23 (12), pp.6660-6666. ⟨10.1021/la063682y⟩
cited By 18; International audience; AFM-based single molecule desorption measurements were performed on surface end-grafted poly(acrylic acid) monolayers as a function of the pH of the aqueous buffer to study the adhesion properties of polymers that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b41c653a639aeac7fb440ce17d051dd
https://pubmed.ncbi.nlm.nih.gov/17489614
https://pubmed.ncbi.nlm.nih.gov/17489614
Publikováno v:
Journal of the American Chemical Society. 128(20)
In this paper, we measure the single chain elasticity of an oligomer single-stranded DNA (ssDNA) in both aqueous and nonaqueous, apolar liquid environments by AFM-based single molecule force spectroscopy. We find a marked deviation between the force-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825dc7660d650420759490f9a807dd34
https://pubmed.ncbi.nlm.nih.gov/16704264
https://pubmed.ncbi.nlm.nih.gov/16704264
Publikováno v:
Physical review letters. 97(21)
The end-to-end distance and the contour length of single polymers in dynamic adsorbate layers were measured with a mechanical approach. Individual polysaccharide chains were covalently pinned to the surface with one segment and picked up randomly wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04059c97f345e33801861937ac35655
https://pubmed.ncbi.nlm.nih.gov/17155778
https://pubmed.ncbi.nlm.nih.gov/17155778