Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Ferdinand, Althammer"'
Autor:
Ferdinand Althammer, Ranjan K. Roy, Matthew K. Kirchner, Yuval Podpecan, Jemima Helen, Shaina McGrath, Elba Campos Lira, Javier E. Stern
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Activation of microglia, the resident immune cells of the central nervous system, leading to the subsequent release of pro-inflammatory cytokines, has been linked to cardiac remodeling, autonomic disbalance, and cognitive deficits in heart f
Externí odkaz:
https://doaj.org/article/8a672b52db894a47ab42ea045dd73e4e
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108243- (2023)
Summary: Neuropeptides are packed into large dense core vesicles (LDCVs) that are transported from the soma out into their processes. Limited information exists regarding mechanisms regulating LDCV trafficking, particularly during challenges to bodil
Externí odkaz:
https://doaj.org/article/8086a6849ee34278a14732ec6ae1838f
Autor:
Tim Gruber, Franziska Lechner, Cahuê Murat, Raian E. Contreras, Eva Sanchez-Quant, Viktorian Miok, Konstantinos Makris, Ophélia Le Thuc, Ismael González-García, Elena García-Clave, Ferdinand Althammer, Quirin Krabichler, Lisa M. DeCamp, Russell G. Jones, Dominik Lutter, Rhiannan H. Williams, Paul T. Pfluger, Timo D. Müller, Stephen C. Woods, John Andrew Pospisilik, Celia P. Martinez-Jimenez, Matthias H. Tschöp, Valery Grinevich, Cristina García-Cáceres
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113305- (2023)
Summary: Oxytocin-expressing paraventricular hypothalamic neurons (PVNOT neurons) integrate afferent signals from the gut, including cholecystokinin (CCK), to adjust whole-body energy homeostasis. However, the molecular underpinnings by which PVNOT n
Externí odkaz:
https://doaj.org/article/90782dfc60ca478ea59744d818a5084b
Autor:
Mai Iwasaki, Arthur Lefevre, Ferdinand Althammer, Etienne Clauss Creusot, Olga Łąpieś, Hugues Petitjean, Louis Hilfiger, Damien Kerspern, Meggane Melchior, Stephanie Küppers, Quirin Krabichler, Ryan Patwell, Alan Kania, Tim Gruber, Matthew K. Kirchner, Moritz Wimmer, Henning Fröhlich, Laura Dötsch, Jonas Schimmer, Sabine C. Herpertz, Beate Ditzen, Christian P. Schaaf, Kai Schönig, Dusan Bartsch, Anna Gugula, Aleksandra Trenk, Anna Blasiak, Javier E. Stern, Pascal Darbon, Valery Grinevich, Alexandre Charlet
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
The hypothalamic neuropeptide oxytocin exerts analgesic effects, but the underlying pathways remain largely elusive. Here, the authors describe an analgesic pathway formed by oxytocin neurons projecting to the periaqueductal grey, where axonally rele
Externí odkaz:
https://doaj.org/article/85fa7e14fa3741ae8af552981e58801d
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The prosocial neuropeptide oxytocin is being developed as a potential treatment for various neuropsychiatric disorders including autism spectrum disorder (ASD). Early studies using intranasal oxytocin in patients with ASD yielded encouraging
Externí odkaz:
https://doaj.org/article/f14f5bb3cc694d638372f71b28296eae
Autor:
Mingkwan Greenwood, Benjamin T. Gillard, Rizwan Farrukh, Alex Paterson, Ferdinand Althammer, Valery Grinevich, David Murphy, Michael P. Greenwood
Publikováno v:
Molecular Metabolism, Vol 63, Iss , Pp 101542- (2022)
Objectives: Dynamic changes to neuropeptide hormone synthesis and secretion by hypothalamic neuroendocrine cells is essential to ensure metabolic homeostasis. The specialised molecular mechanisms that allow neuroendocrine cells to synthesise and secr
Externí odkaz:
https://doaj.org/article/643d551f0e874f83a8efb9ddbc1bffd1
Autor:
Ferdinand Althammer, Hildebrando Candido Ferreira-Neto, Myurajan Rubaharan, Ranjan K. Roy, Atit A. Patel, Daniel N. Cox, Javier E. Stern
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-19 (2020)
Abstract Background Cardiovascular diseases, including heart failure, are the most common cause of death globally. Recent studies support a high degree of comorbidity between heart failure and cognitive and mood disorders resulting in memory loss, de
Externí odkaz:
https://doaj.org/article/5dc52cfc25e549bd962955445536ae20
Autor:
Ferdinand Althammer, Eric G. Krause, Anette D. de Kloet, Justin Smith, Valery Grinevich, Alexandre Charlet, Javier E. Stern
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101160- (2022)
Summary: Here, we present a step-by-step protocol for three-dimensional reconstruction of astrocyte morphology, applied to the central amygdala oxytocin receptor-expressing astrocytes. This includes RNAse-free perfusion, combination of RNAscope and i
Externí odkaz:
https://doaj.org/article/4ddad5276e15406fb78657ab964df402
Autor:
Ranjan K. Roy, Ferdinand Althammer, Alexander J. Seymour, Wenting Du, Vinicia C. Biancardi, Jordan P. Hamm, Jessica A. Filosa, Colin H. Brown, Javier E. Stern
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109925- (2021)
Summary: Neurovascular coupling (NVC), the process that links neuronal activity to cerebral blood flow changes, has been mainly studied in superficial brain areas, namely the neocortex. Whether the conventional, rapid, and spatially restricted NVC re
Externí odkaz:
https://doaj.org/article/0f6ae9760d764ee28bc97bde1ff6691a
Autor:
Ferdinand Althammer, Ranjan K. Roy, Matthew K. Kirchner, Elba Campos-Lira, Kathryn E. Whitley, Steven Davis, Juliana Montanez, Hildebrando Candido Ferreira-Neto, Jessica Danh, Rafaela Feresin, Vinicia Campana Biancardi, Usama Zafar, Marise B. Parent, Javier E. Stern
Publikováno v:
Hypertension. 80:1258-1273
Background: Heart failure (HF) is a debilitating disease affecting >64 million people worldwide. In addition to impaired cardiovascular performance and associated systemic complications, most patients with HF suffer from depression and substantial co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11660fa144e94c7020fb79a713097f6c
https://doi.org/10.1161/hypertensionaha.123.21070
https://doi.org/10.1161/hypertensionaha.123.21070