Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ferdi van der Pijl"'
Publikováno v:
Bioorganic & Medicinal Chemistry, 23, 2721-2729
Bioorganic & Medicinal Chemistry, 23, 11, pp. 2721-2729
Bioorganic & Medicinal Chemistry, 23, 11, pp. 2721-2729
We have synthesized biologically relevant 6-aza-8-oxa[3.2.1]bicyclooctane scaffolds in a five-step procedure starting from furfural. Besides showing that these scaffolds are amenable to decoration via standard functional group interconversions, we al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a83d1573034562d6a0253dd04c0fa9
https://doi.org/10.1016/j.bmc.2014.12.045
https://doi.org/10.1016/j.bmc.2014.12.045
Publikováno v:
European Journal of Organic Chemistry. 2015:4811-4829
Amongst the various conversions that are known to transform the furan moiety into other functional groups or heterocyclic rings, the Achmatowicz reaction and the corresponding aza-modification stand out as broadly applicable oxidative rearrangements.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceab96dc9b2f47e9753a62ca938ee445
https://doi.org/10.1002/ejoc.201500321
https://doi.org/10.1002/ejoc.201500321
Autor:
Ferdi van der Pijl, Floris L. van Delft, Floris P. J. T. Rutjes, Robert K. Harmel, Gaston J. J. Richelle, Peter Janssen
Publikováno v:
Organic Letters, 16, 2038-2041
Organic Letters, 16, 7, pp. 2038-2041
Organic Letters, 16, 7, pp. 2038-2041
Enantiomerically pure 2,6-disubstituted piperidinones were synthesized from furfural involving an organocatalyzed Mannich reaction, aza-Achmatowicz reaction, and an N-acyliminium ion-mediated coupling step. This approach was also successfully applied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebfd9d46239515a89fdce928bbe0234d
https://doi.org/10.1021/ol500633u
https://doi.org/10.1021/ol500633u
Autor:
Marian M. J. H. P. Willems, Floris L. van Delft, Ferdi van der Pijl, Jorge M. M. Verkade, Floris P. J. T. Rutjes, Peter J. L. M. Quaedflieg
Publikováno v:
Journal of Organic Chemistry, 74, 3207-3210
Journal of Organic Chemistry, 74, 8, pp. 3207-3210
Journal of Organic Chemistry, 74, 8, pp. 3207-3210
A concise stereoselective route providing access to both enantiomers of the bioactive quinolizidine alkaloid lasubine II has been developed. The enantioselectivity was introduced by taking advantage of a proline-catalyzed asymmetric Mannich reaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e3ad9163363edca482605671ec0519
https://doi.org/10.1021/jo900141f
https://doi.org/10.1021/jo900141f
Publikováno v:
ChemInform. 46
Amongst the various conversions that are known to transform the furan moiety into other functional groups or heterocyclic rings, the Achmatowicz reaction and the corresponding aza-modification stand out as broadly applicable oxidative rearrangements.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b9a6dbc3ca44ae554812a0fae5420ba
https://doi.org/10.1002/chin.201537282
https://doi.org/10.1002/chin.201537282
Autor:
Robert K. Harmel, Peter Janssen, Floris L. van Delft, Gaston J. J. Richelle, Floris P. J. T. Rutjes, Ferdi van der Pijl
Publikováno v:
ChemInform. 45
(-)-Sedacryptine (XIII) and its epimer (XVI) are prepared via organocatalyzed Mannich, aza-Achmatowicz, and an N-acyliminium ion addition reaction from boc-protected furanyl amines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ecc5a9e3ab07650827b8b801eb535d2
https://doi.org/10.1002/chin.201437173
https://doi.org/10.1002/chin.201437173