NAD ⁺ deficiency plays essential roles in the hyperuricemia of stroke-prone spontaneously hypertensive rat via xanthine dehydrogenase to xanthine oxidase conversion.

Autor: Ferdaus SA; Department of Internal Medicine 1, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, Shimane, 693-8501, Japan., Ohara H; Department of Functional Pathology, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, Shimane, 693-8501, Japan., Matsuo H; Institute of Experimental Animals, Interdisciplinary Center for Science Research, Head Office for research and academic Information, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, Shimane, 693-8501, Japan., Kawakami K; Institute of Experimental Animals, Interdisciplinary Center for Science Research, Head Office for research and academic Information, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, Shimane, 693-8501, Japan., Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo, 162-8655, Japan., Fujikawa K; Department of Functional Pathology, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, Shimane, 693-8501, Japan., Kawakita E; Department of Internal Medicine 1, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, Shimane, 693-8501, Japan., Kato N; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo, 162-8655, Japan., Nabika T; Department of Functional Pathology, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, Shimane, 693-8501, Japan., Kanasaki K; Department of Internal Medicine 1, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, Shimane, 693-8501, Japan; The Center for Integrated Kidney Research and Advance, Faculty of Medicine, Shimane University, 89-1 Enya-cho, Izumo, 693-8501, Japan. Electronic address: kkanasak@med.shimane-u.ac.jp.

Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Dec 12; Vol. 744, pp. 151136. Date of Electronic Publication: 2024 Dec 12.