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pro vyhledávání: '"Feola, S."'
Akademický článek
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Cancer Immunotherapy relies on harnessing a patient's immune system to fine-tune specific anti-tumor responses and ultimately eradicate cancer. Among diverse therapeutic approaches, oncolytic viruses (OVs) have emerged as a novel form of cancer immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1593::db83d263c8aeff2d80653f88f053bc35
http://hdl.handle.net/10138/342610
http://hdl.handle.net/10138/342610
Autor:
Peltonen K., Feola S., Umer H. M., Chiaro J., Mermelekas G., Ylosmaki E., Pesonen S., Branca R. M. M., Lehtio J., Cerullo V.
Knowledge of clinically targetable tumor antigens is becoming vital for broader design and utility of therapeutic cancer vaccines. This information is obtained reliably by directly interro-gating the MHC-I presented peptide ligands, the immunopeptido
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3730::39a4faf39596e6be47db58aa106c191c
http://hdl.handle.net/11588/879825
http://hdl.handle.net/11588/879825
Autor:
Hamdan F., Martins B., Feodoroff M., Giannoula Y., Feola S., Fusciello M., Chiaro J., Antignani G., Gronholm M., Ylosmaki E., Cerullo V.
Oncolytic adenoviruses have become ideal agents in the path toward treating cancer. Such viruses have been engineered to conditionally replicate in malignant cells in which certain signaling pathways have been disrupted. Other than such oncolytic pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3730::c5821588e771b63050fee4cf2fcf6fd5
http://hdl.handle.net/11588/879834
http://hdl.handle.net/11588/879834
Autor:
Ylosmaki E., Ylosmaki L., Fusciello M., Martins B., Ahokas P., Cojoc H., Uoti A., Feola S., Kreutzman A., Ranki T., Karbach J., Viitala T., Priha P., Jager E., Pesonen S., Cerullo V.
Ylösmäki et al. develop an oncolytic adenovirus expressing immunostimulatory cytokines OX40L and CD40L. This virus was tested in a peptide-based cancer vaccine platform called PeptiCRAd. Intratumoral administration of PeptiCRAd induced systemic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3730::6a6c7a77a62090b0ca0c0115774a5557
http://hdl.handle.net/11588/879839
http://hdl.handle.net/11588/879839
Autor:
Ylosmaki E., Fusciello M., Martins B., Feola S., Hamdan F., Chiaro J., Ylosmaki L., Vaughan M. J., Viitala T., Kulkarni P. S., Cerullo V.
Background Intratumoral BCG therapy, one of the earliest immunotherapies, can lead to infiltration of immune cells into a treated tumor. However, an increase in the number of BCG-induced tumor-specific T cells in the tumor microenvironment could lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3730::4d6f596a1776381c6c98a6f64038761d
http://hdl.handle.net/11588/879830
http://hdl.handle.net/11588/879830
Autor:
Chiaro J., Kasanen H. H. E., Whalley T., Capasso C., Gronholm M., Feola S., Peltonen K., Hamdan F., Hernberg M., Makela S., Karhapaa H., Brown P. E., Martins B., Fusciello M., Ylosmaki E. O., Greco D., Kreutzman A. S., Mustjoki S., Szomolay B., Cerullo V.
Molecular mimicry is one of the leading mechanisms by which infectious agents can induce autoimmunity. Whether a similar mechanism triggers an antitumor immune response is unexplored, and the role of antiviral T cells infiltrating the tumor has remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3730::a229c4f24ebaa34a87cd726e40551f1d
http://hdl.handle.net/11588/879829
http://hdl.handle.net/11588/879829
Publikováno v:
Pharmacology & Therapeutics
Cancer Immunotherapy relies on harnessing a patient's immune system to fine-tune specific anti-tumor responses and ultimately eradicate cancer. Among diverse therapeutic approaches, oncolytic viruses (OVs) have emerged as a novel form of cancer immun
Akademický článek
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Akademický článek
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