Výsledky vyhledávání

In vitro Inhibition of Methadone and Oxycodone Cytochrome P450-Dependent Metabolism: Reversible Inhibition by H2-Receptor Agonists and Proton-Pump Inhibitors

Autor: David E. Moody, Fenyun Liu, Wenfang B. Fang

Publikováno v: Journal of Analytical Toxicology. 37:476-485

In vitro inhibition of oxycodone metabolism to noroxycodone and oxymorphone and R- and S-methadone metabolism to R- and S-2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) was measured for four H2-receptor antagonists and five proton-pump inhi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1454737b0950cdeec7dab60de18c48
https://doi.org/10.1093/jat/bkt060

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Azole antifungal inhibition of buprenorphine, methadone and oxycodone in vitro metabolism

Autor: Wenfang B. Fang, Fenyun Liu, David E. Moody

Publikováno v: Journal of analytical toxicology. 39(5)

Opioid-related mortality rates have escalated. Drug interactions may increase blood concentrations of the opioid. We therefore used human liver microsomes (HLMs) and cDNA-expressed human cytochrome P450s (rCYPs) to study in vitro inhibition of bupren

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3715d84fb7b1d915a62a069f17b03a4
https://pubmed.ncbi.nlm.nih.gov/25868557

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Inhibition of Buprenorphine Metabolism by Proton Pump Inhibitors: Enigmatic Time‐Dependent Effect of Esomeprazole (LB594)

Autor: Fenyun Liu, Wenfang Fang, David Moody

Publikováno v: The FASEB Journal. 28

While several studies have investigated the effect of proton pump inhibitors (PPI) on the activities of specific cytochrome P450s (CYP450), most studies used model substrates. Here we investigate t...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1dc1c098bfd49f05db4a8a0ffaa09da4
https://doi.org/10.1096/fasebj.28.1_supplement.lb594

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Subtyping Salmonella enterica serovar enteritidis isolates from different sources by using sequence typing based on virulence genes and clustered regularly interspaced short palindromic repeats (CRISPRs)

Autor: Bhushan M. Jayarao, Fenyun Liu, Edward G. Dudley, Efrain M. Ribot, Rodolphe Barrangou, Subhashinie Kariyawasam, Stephen J. Knabel, Peter Gerner-Smidt

Publikováno v: Applied and environmental microbiology. 77(13)

Salmonella enterica subsp. enterica serovar Enteritidis is a major cause of food-borne salmonellosis in the United States. Two major food vehicles for S . Enteritidis are contaminated eggs and chicken meat. Improved subtyping methods are needed to ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d301c9138887869c8c6c55f468f017
https://pubmed.ncbi.nlm.nih.gov/21571881

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Novel virulence gene and clustered regularly interspaced short palindromic repeat (CRISPR) multilocus sequence typing scheme for subtyping of the major serovars of Salmonella enterica subsp. enterica

Autor: Stephen J. Knabel, Peter Gerner-Smidt, Efrain M. Ribot, Fenyun Liu, Edward G. Dudley, Rodolphe Barrangou

Publikováno v: Applied and environmental microbiology. 77(6)

Salmonella enterica subsp. enterica is the leading cause of bacterial food-borne disease in the United States. Molecular subtyping methods are powerful tools for tracking the farm-to-fork spread of food-borne pathogens during outbreaks. In order to d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d36835b9edf8b697d6e7f2c512f2660
https://pubmed.ncbi.nlm.nih.gov/21278266

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Akademický článek

Azole Antifungal Inhibition of Buprenorphine, Methadone and Oxycodone In Vitro Metabolism.

Autor: Moody, David E., Fenyun Liu, Fang, Wenfang B.

Publikováno v: Journal of Analytical Toxicology; Jun2015, Vol. 39 Issue 5, p374-386, 13p

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Akademický článek

In vitro Inhibition of Methadone and Oxycodone Cytochrome P450-Dependent Metabolism: Reversible Inhibition by H2-Receptor Agonists and Proton-Pump Inhibitors.

Autor: Moody, David E., Fenyun Liu, Wenfang B. Fang

Publikováno v: Journal of Analytical Toxicology; Oct2013, Vol. 37 Issue 8, p476-485, 10p

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Akademický článek

Subtyping Salmonella enterica Serovar Enteritidis Isolated from Different Sources by Using Sequence Typing Based on Virulence Genes and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRS).

Autor: Fenyun Liu¹, Kariyawasam, Subhashinie^2,3, Jayarao, Bhushan M.^2,3, Barrangou, Rodolphe^1,4, Gerner-Smidt, Peter⁵, Ribot, Efrain M.⁵, Knabel, Stephen J.¹, Dudley, Edward G.¹ egd100@psu.edu

Publikováno v: Applied & Environmental Microbiology. Jul2011, Vol. 77 Issue 13, p4520-4526. 7p.

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Akademický článek

Novel Virulence Gene and Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Multilocus Sequence Typing Scheme for Subtyping of the Major Serovars of Salmonella enterica subsp. enterica.

Autor: Fenyun Liu¹ (AUTHOR), Barrangou, Rodolphe^1,2 (AUTHOR), Gerner-Smidt, Peter³ (AUTHOR), Ribot, Efrain M.³ (AUTHOR), Knabel, Stephen J.¹ (AUTHOR), Dudley, Edward G.¹ (AUTHOR) egd100@psu.edu

Publikováno v: Applied & Environmental Microbiology. Mar2011, Vol. 77 Issue 6, p1946-1956. 11p.

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