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417–2α-Tocopherol and ascorbic acid attenuates the ribavirin-induced decrease of eicosapentaenoic acid in erythrocyte membrane in chronic hepatitis C patients

Autor: Yuichi Hara, Yuhki Yamaguchi, Keisuke Hino, Michiari Okuda, Kohki Yutoku, Fenyu Ren, Kiwamu Okita, Takakazu Furutani, Yasuko Murakami, Ayako Nagai, Akira Kitase, Misako Okita, Satoyoshi Yamashita

Publikováno v: Journal of Gastroenterology and Hepatology. 21:1269-1275

Background: Oxidative damage of the erythrocyte membrane plays an important role in ribavirin-induced anemia. The purpose of the present paper was to assess whether supplementation of α-tocopherol and ascorbic acid (vitamins) causes changes in the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::113fc4fd605616af539b584712cee0bc
https://doi.org/10.1111/j.1440-1746.2006.04378.x

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Cytokine-dependent anti-viral role of CD4-positive T cells in therapeutic vaccination against chronic hepatitis B viral infection

Autor: Kiwamu Okita, Yuhki Yamaguchi, Hiroaki Ishiko, Keiko Korenaga, Keisuke Hino, Takahiro Yamasaki, Akio Hayashi, Kiyomi Funatsuki, Fenyu Ren, Muneko Furutani, Tomomi Konishi, Satoyoshi Yamashita

Publikováno v: Journal of Medical Virology. 71:376-384

There are several lines of evidence suggesting that specific vaccine therapy with a standard hepatitis B virus (HBV) vaccination reduces HBV replication. The aim of this study was to investigate the anti-viral mechanism of vaccine therapy in chronic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4fe75cb00136b8e17ace421f38761c
https://doi.org/10.1002/jmv.10509

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Autor: Yasuhiro Satoh, D. Fujiwara, Yuhki Yamaguchi, Keisuke Hino, Yoshiharu Katoh, Kiwamu Okita, Fenyu Ren

Publikováno v: Digestive Diseases and Sciences. 47:1611-1617

To assess whether peripheral blood mononuclear cells (PBMCs) can be substituted for liver tissue in monitoring the hepatic expression of interferon receptors (IFNAR1 and/or IFNAR2) in chronic hepatitis C, we quantified the mRNA of both subunits, usin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7af291a47f999ee07c302537a4e4ce9b
https://doi.org/10.1023/a:1015887723557

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Alpha-tocopherol [corrected] and ascorbic acid attenuates the ribavirin [corrected] induced decrease of eicosapentaenoic acid in erythrocyte membrane in chronic hepatitis C patients

Autor: Keisuke, Hino, Yasuko, Murakami, Ayako, Nagai, Akira, Kitase, Yuichi, Hara, Takakazu, Furutani, Fenyu, Ren, Yuhki, Yamaguchi, Kohki, Yutoku, Satoyoshi, Yamashita, Michiari, Okuda, Misako, Okita, Kiwamu, Okita

Publikováno v: Journal of gastroenterology and hepatology. 21(8)

Oxidative damage of the erythrocyte membrane plays an important role in ribavirin-induced anemia. The purpose of the present paper was to assess whether supplementation of alpha-tocopherol and ascorbic acid (vitamins) causes changes in the erythrocyt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::25f6fc04f1f2083e9d242892e233a8cc
https://pubmed.ncbi.nlm.nih.gov/16872308

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Hepatic expression of type I interferon receptor for predicting response to interferon therapy in chronic hepatitis C patients: a comparison of immunohistochemical method vs. competitive polymerase chain reaction assay

Autor: Masaaki Korenaga, Yasuhiro Satoh, Fenyu Ren, D. Fujiwara, Kiwamu Okita, Yuhki Yamaguchi, Keisuke Hino, Michiari Okuda

Publikováno v: Hepatology research : the official journal of the Japan Society of Hepatology. 25(4)

The focus of this study is to determine both mRNA and protein expression levels of the type I interferon (IFN) receptor subunits, IFNα receptor (IFNAR1) and IFNα/β receptor (IFNAR2), in the liver, and to assess which quantification method is most

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8488f6aad1df13d880f6502a363f881
https://pubmed.ncbi.nlm.nih.gov/12699848

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