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of 2
pro vyhledávání: '"Fenny H.F. Tang"'
Nna1 gene deficiency triggers Purkinje neuron death by tubulin hyperglutamylation and ER dysfunction
Autor:
Jianxue Li, Evan Y. Snyder, Fenny H.F. Tang, Renata Pasqualini, Wadih Arap, Richard L. Sidman
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
Posttranslational glutamylation/deglutamylation balance in tubulins influences dendritic maturation and neuronal survival of cerebellar Purkinje neurons (PNs). PNs and some additional neuronal types degenerate in several spontaneous, independently oc
Externí odkaz:
https://doaj.org/article/ae2da415ddf04f47b7b57947e2315661
Autor:
Christopher Markosian, Daniela I. Staquicini, Prashant Dogra, Esteban Dodero-Rojas, Joseph H. Lubin, Fenny H.F. Tang, Tracey L. Smith, Vinícius G. Contessoto, Steven K. Libutti, Zhihui Wang, Vittorio Cristini, Sagar D. Khare, Paul C. Whitford, Stephen K. Burley, José N. Onuchic, Renata Pasqualini, Wadih Arap
Publikováno v:
Molecular Biology and Evolution. 39
Evaluation of immunogenic epitopes for universal vaccine development in the face of ongoing SARS-CoV-2 evolution remains a challenge. Herein, we investigate the genetic and structural conservation of an immunogenically relevant epitope (C662–C671)