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Population pharmacokinetics of total and unbound teicoplanin concentrations and dosing simulations in patients with haematological malignancy.

Autor: Byrne CJ; School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Ireland., Parton T; Mekinopsis Ltd, London, UK., McWhinney B; Pathology Queensland, Brisbane, Australia., Fennell JP; Tallaght Hospital, Dublin, Ireland., O'Byrne P; Tallaght Hospital, Dublin, Ireland., Deasy E; Tallaght Hospital, Dublin, Ireland., Egan S; Tallaght Hospital, Dublin, Ireland., Enright H; Tallaght Hospital, Dublin, Ireland., Desmond R; Tallaght Hospital, Dublin, Ireland., Ryder SA; School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Ireland., D'Arcy DM; School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Ireland., McHugh J; Tallaght Hospital, Dublin, Ireland., Roberts JA; University of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Australia.; Centre for Translational Anti-Infective Pharmacodynamics, School of Pharmacy, The University of Queensland, Brisbane, Australia.

Publikováno v: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2018 Apr 01; Vol. 73 (4), pp. 995-1003.

Variability in Trough Total and Unbound Teicoplanin Concentrations and Achievement of Therapeutic Drug Monitoring Targets in Adult Patients with Hematological Malignancy.

Autor: Byrne CJ; School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland., Roberts JA; Burns, Trauma and Critical Care Research Centre, The University of Queensland, Brisbane, Australia.; Centre for Translational Anti-Infective Pharmacodynamics, The University of Queensland, Brisbane, Australia., McWhinney B; Queensland Pathology, Brisbane, Australia., Fennell JP; Tallaght Hospital, Dublin, Ireland., O'Byrne P; Tallaght Hospital, Dublin, Ireland., Deasy E; Tallaght Hospital, Dublin, Ireland., Egan S; Tallaght Hospital, Dublin, Ireland., Desmond R; Tallaght Hospital, Dublin, Ireland., Enright H; Tallaght Hospital, Dublin, Ireland., Ryder SA; School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland sryder@tcd.ie., D'Arcy DM; School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland., McHugh J; Tallaght Hospital, Dublin, Ireland.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2017 May 24; Vol. 61 (6). Date of Electronic Publication: 2017 May 24 (Print Publication: 2017).

Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection.

Autor: Brown AF; Host-Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Murphy AG; Host-Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Lalor SJ; Host-Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Leech JM; Host-Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., O'Keeffe KM; Host-Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Mac Aogáin M; Department of Clinical Microbiology, School of Medicine, Trinity College Dublin, Dublin, Ireland., O'Halloran DP; Department of Microbiology, Moyne Institute of Preventive Medicine, School of Genetics and Microbiology, Trinity College Dublin, Dublin, Ireland., Lacey KA; Host-Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Tavakol M; Department of Medical Microbiology & Infectious Diseases, Erasmus Medical Center, Rotterdam, Netherlands., Hearnden CH; Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Fitzgerald-Hughes D; Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Dublin, Ireland., Humphreys H; Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Dublin, Ireland.; Department of Microbiology, Beaumont Hospital, Dublin, Ireland., Fennell JP; Department of Clinical Microbiology, School of Medicine, Trinity College Dublin, Dublin, Ireland.; Department of Clinical Microbiology, Adelaide Meath & National Children's Hospital, Dublin, Ireland., van Wamel WJ; Department of Medical Microbiology & Infectious Diseases, Erasmus Medical Center, Rotterdam, Netherlands., Foster TJ; Department of Microbiology, Moyne Institute of Preventive Medicine, School of Genetics and Microbiology, Trinity College Dublin, Dublin, Ireland., Geoghegan JA; Department of Microbiology, Moyne Institute of Preventive Medicine, School of Genetics and Microbiology, Trinity College Dublin, Dublin, Ireland., Lavelle EC; Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.; Advanced Materials and Bioengineering Research Centre (AMBER), Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Trinity College Dublin, Dublin, Ireland., Rogers TR; Department of Clinical Microbiology, School of Medicine, Trinity College Dublin, Dublin, Ireland.; Department of Clinical Microbiology, St. James's Hospital, Dublin, Ireland., McLoughlin RM; Host-Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.

Publikováno v: PLoS pathogens [PLoS Pathog] 2015 Nov 05; Vol. 11 (11), pp. e1005226. Date of Electronic Publication: 2015 Nov 05 (Print Publication: 2015).