Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fenja Amrei Schuran"'
Publikováno v:
Seminars in Immunopathology
The aryl hydrocarbon receptor (AHR) is a ubiquitously expressed ligand-activated transcription factor with multifaceted physiological functions. In the immune system, AHR has been unequivocally identified as a key regulatory factor that can integrate
Autor:
Tobias Poch, Johannes Herkel, Luisa Marie Müller, Romina Fiorotto, Antonella Carambia, Till Krech, Lutz Fischer, Dorothee Schwinge, Mario Strazzabosco, S Stein, Lara Henze, Jun Li, M Reich, Nicola Gagliani, M Preti, Christoph Schramm, Verena Keitel, Jonas Wagner, Fenja Amrei Schuran
Publikováno v:
J Hepatol
Background & Aims IL-17A-producing T cells are present in autoimmune cholestatic liver diseases; however, little is known about the contribution of IL-17 to periductal immune responses. Herein, we investigated the role of IL-17 produced by antigen-sp
Autor:
Fenja Amrei Schuran, Ansgar W. Lohse, Carlotta Corban, Disha Mungalpara, Muharrem Şeleci, Joerg Heeren, Cornelia Gottwick, Johannes Herkel, Markus Heine, Antonella Carambia, Dorothee Schwinge, S Stein, Christoph Schramm, Reinaldo Digigow
Publikováno v:
Immunology
Summary Autoimmune diseases are caused by adaptive immune responses to self‐antigens. The development of antigen‐specific therapies that suppress disease‐related, but not unrelated immune responses in general, is an important goal of biomedical
Autor:
S Stein, B Höh, F Glaser, Fenja Amrei Schuran, Antonella Carambia, Johannes Herkel, Dorothee Schwinge, Jan Dieckhoff, Ansgar W. Lohse, Christoph Schramm, Christian Casar, Nathalie Becker, Bastian Engel, Joerg Heeren, Andre Franke, Harald Ittrich, Clara John, Björn Wieschendorf, M Preti, Friederike Jessen, Sören Weidemann
Publikováno v:
Journal of Hepatology. 71:783-792
Background & Aims T cells are central mediators of liver inflammation and represent potential treatment targets in cholestatic liver disease. Whereas emerging evidence shows that bile acids (BAs) affect T cell function, the role of T cells for the re
Autor:
Christoph Schramm, Anna-Lena Müller, Fenja Amrei Schuran, Daria Krzikalla, Tobias Poch, Christina Weiler-Normann, Johannes Herkel, Antonella Carambia, Dorothee Schwinge, David Lübbering, Ansgar W. Lohse, Marcial Sebode, Miriam Schakat, Sören Weidemann, Lena Schlott, M Preti
Publikováno v:
JCI Insight
JCI Insight, Vol 6, Iss 6 (2021)
JCI Insight, Vol 6, Iss 6 (2021)
The liver is an immune-privileged organ that can deactivate autoreactive T cells. Yet in autoimmune hepatitis (AIH), autoreactive T cells can defy hepatic control and attack the liver. To elucidate how tolerance to self-antigens is lost during AIH pa
Autor:
Fenja Amrei Schuran, A Steudter, Ansgar W. Lohse, C Lommetz, Antonella Carambia, Dorothee Schwinge, Christoph Schramm, Björn Wieschendorf, Johannes Herkel
Publikováno v:
Zeitschrift für Gastroenterologie.
Autor:
Fenja Amrei Schuran, M Şeleci, Antonella Carambia, Johannes Herkel, Dorothee Schwinge, Ansgar W. Lohse, Christoph Schramm, Jörg Heeren, M Heine, C Gottwick, D Mungalpara, R Digigow, S Stein
Publikováno v:
Zeitschrift für Gastroenterologie.
Autor:
Andreas Steudter, Joerg Heeren, Ahmed Ghallab, Joerg Reinders, Johannes Herkel, Björn Wieschendorf, Antonella Carambia, Christoph Schramm, Dorothee Schwinge, Sebastian Zuehlke, Ansgar W. Lohse, Christoph Lommetz, Fenja Amrei Schuran
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, 11(2):371-388
Cellular and Molecular Gastroenterology and Hepatology, 11(2):371-388
Background & Aims Acetaminophen (APAP)-induced liver injury is one of the most common causes of acute liver failure, however, a clear definition of sensitizing risk factors is lacking. Here, we investigated the role of the ligand-activated transcript
Publikováno v:
Immunity, Inflammation and Disease. 6:354-370
INTRODUCTION Recently, we found abundant innervation of antigen presenting cells that were reached and enclosed by single neurites. These neurally hard-wired antigen presenting cells (wAPC) could be observed in the T-cell zone of superficial cervical