Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Fengzhi Jin"'
Autor:
Aaron M. Rosado, Yan Zhang, Hyun-Kyu Choi, Yunfeng Chen, Samuel M. Ehrlich, Fengzhi Jin, Arash Grakoui, Brian D. Evavold, Cheng Zhu
Publikováno v:
APL Bioengineering, Vol 7, Iss 1, Pp 016102-016102-17 (2023)
Interactions between proteins coordinate biological processes in an organism and may impact its responses to changing environments and diseases through feedback systems. Feedback systems function by using changes in the past to influence behaviors in
Externí odkaz:
https://doaj.org/article/5aae22cc85894f19ac854ed479664ab0
Autor:
Abigail Vanderheiden, Jeronay Thomas, Allison L. Soung, Meredith E. Davis-Gardner, Katharine Floyd, Fengzhi Jin, David A. Cowan, Kathryn Pellegrini, Adrian Creanga, Amarendra Pegu, Alexandrine Derrien-Colemyn, Pei-Yong Shi, Arash Grakoui, Robyn S. Klein, Steven E. Bosinger, Jacob E. Kohlmeier, Vineet D. Menachery, Mehul S. Suthar
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
Externí odkaz:
https://doaj.org/article/12d5b5bafec94e74979569fbd9832892
Autor:
Abigail Vanderheiden, Jeronay Thomas, Allison L. Soung, Meredith E. Davis-Gardner, Katharine Floyd, Fengzhi Jin, David A. Cowan, Kathryn Pellegrini, Adrian Creanga, Amarendra Pegu, Alexandrine Derrien-Colemyn, Pei-Yong Shi, Arash Grakoui, Robyn S. Klein, Steven E. Bosinger, Jacob E. Kohlmeier, Vineet D. Menachery, Mehul S. Suthar
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a historic pandemic of respiratory disease (coronavirus disease 2019 [COVID-19]), and current evidence suggests that severe disease is associated with dysregulated immun
Externí odkaz:
https://doaj.org/article/338d7fe83d2f443ab2dd478f383e3881
Publikováno v:
Cell Reports, Vol 14, Iss 5, Pp 1074-1085 (2016)
Summary: The spindle assembly checkpoint (SAC) monitors chromosome attachment defects, and the assembly of SAC proteins at kinetochores is essential for its activation, but the SAC disassembly process remains unknown. We found that deletion of a 14-3
Externí odkaz:
https://doaj.org/article/7bcfa525b88e447c856a07b286dd5576
Publikováno v:
PLoS Genetics, Vol 8, Iss 2, p e1002492 (2012)
The attachment of sister kinetochores by microtubules emanating from opposite spindle poles establishes chromosome bipolar attachment, which generates tension on chromosomes and is essential for sister-chromatid segregation. Syntelic attachment occur
Externí odkaz:
https://doaj.org/article/589b765b3fab45ec942ecd1ec381d136
Publikováno v:
PLoS Genetics, Vol 4, Iss 11, p e1000262 (2008)
The kinetochore is a protein complex that assembles on centromeric DNA to mediate chromosome-microtubule interaction. Most eukaryotic cells form the spindle and establish kinetochore-microtubule interaction during mitosis, but budding yeast cells fin
Externí odkaz:
https://doaj.org/article/adadf44495af4a4da949f6a385dc6e3f
Autor:
Aaron M. Rosado, Yan Zhang, Hyun-Kyu Choi, Samuel M. Ehrlich, Fengzhi Jin, Arash Grakoui, Brian D. Evavold, Cheng Zhu
Over the past three decades, the senior author had interacted with and been mentored by the late Professor Robert M. Nerem. In his memory, the authors summarized several observations made, ideas conceptualized, and mathematical models developed durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddaae7c7193a02f9442527a253d95702
https://doi.org/10.1101/2022.10.01.510459
https://doi.org/10.1101/2022.10.01.510459
Autor:
Steven E. Bosinger, Fengzhi Jin, Pei Yong Shi, Jacob E. Kohlmeier, Jeronay Thomas, Vineet D. Menachery, Abigail Vanderheiden, Robyn S. Klein, David A Cowan, Kathryn L. Pellegrini, Meredith E. Davis-Gardner, Arash Grakoui, Allison Soung, Katharine Floyd, Mehul S. Suthar
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
mBio
mBio
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a historic pandemic of respiratory disease (coronavirus disease 2019 [COVID-19]), and current evidence suggests that severe disease is associated with dysregulated immunity withi
Publikováno v:
Molecular biology of the cell. 32(22)
DNA replication stress activates the S-phase checkpoint that arrests the cell cycle, but it is poorly understood how cells recover from this arrest. Cyclin-dependent kinase (CDK) and protein phosphatase 2A (PP2A) are key cell cycle regulators, and Cd
Cell-intrinsic MAVS promotes antigen specific CD8+ T cell proliferation and mitochondrial metabolism
Autor:
Abigail Vanderheiden, Renan Aguliar Valenzuela, Hans Verkerke, Fengzhi Jin, Madeline Price, Jeremy M Boss, Arash Grakoui, Mehul S Suthar
Publikováno v:
The Journal of Immunology. 206:103.07-103.07
Mitochondrial antiviral signaling protein (MAVS), the central adaptor protein for RIG-I like receptor (RLR) signaling, is essential for promoting innate immunity against RNA virus infections. MAVS is ubiquitously expressed, however its function in T