Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Fengyun Ni"'
Autor:
Qingqing Xie, Zhao Wang, Fengyun Ni, Xiaorui Chen, Jianpeng Ma, Nita Patel, Hanxin Lu, Ye Liu, Jing-Hui Tian, David Flyer, Michael J Massare, Larry Ellingsworth, Gregory Glenn, Gale Smith, Qinghua Wang
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0210749 (2019)
Globally, human respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections in newborns, young children, and the elderly for which there is no vaccine. The RSV fusion (F) glycoprotein is a major target for vaccine devel
Externí odkaz:
https://doaj.org/article/cfdeb2d3629d4702a3334786e4caba93
Publikováno v:
Cell Reports, Vol 3, Iss 6, Pp 1910-1920 (2013)
Spontaneous nucleation of actin is very inefficient in cells. To overcome this barrier, cells have evolved a set of actin filament nucleators to promote rapid nucleation and polymerization in response to specific stimuli. However, the molecular mecha
Externí odkaz:
https://doaj.org/article/a1ce374f19194b788bbedfd887044f94
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134576 (2015)
In June 2013, the first human infection by avian influenza A(H6N1) virus was reported in Taiwan. This incident raised the concern for possible human epidemics and pandemics from H6 viruses. In this study, we performed structural and functional invest
Externí odkaz:
https://doaj.org/article/c37bebd0fcfd47dca3be38beef992d29
Many Cryo-EM datasets contain structural heterogeneity due to functional or nonfunctional dynamics that conventional reconstruction methods may fail to resolve. Here we propose a new method, OPUS-DSD (Deep Structural Disentanglement), which can relia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc8353c247f0d464da09006de59621b
These repositories contains the trained models and heterogeneity analysis results which are presentedin the paper:OPUS-DSD: Deep Structural Disentanglement for cryo-EM Single Particle Analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474412be135b66b9aa756158352a1eba
synthetic cryo-EM datasets for NEXT complex, j43 corresponds to data with SNR0.05, run_data is the consensus refinement result for j43. j55 corresponds to data with SNR 0.1, run_55 is the consensus refinement result for j55.4699-bin2.mrcs is the real
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f5723e69fb64a124136345790dea40
cryo-EM datasets for NEXT complex, j43 with SNR0.05, j55 with SNR 0.1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b06b25f2ef9af3561f9a0f1ec367e9f
Publikováno v:
Virology. 513:98-107
Influenza pandemic occurs when a new strain from other animal species overcomes the inter-species barriers and supports rapid human-to-human transmission. A critical prerequisite to this process is that hemagglutinin (HA) acquires a few key mutations
Autor:
Xiaorui Chen, Jing-Hui Tian, Gale Smith, Jianpeng Ma, Ye Liu, Zhao Wang, Hanxin Lu, Fengyun Ni, Gregory M. Glenn, David Flyer, Nita Patel, Qinghua Wang, Qingqing Xie, Michael J. Massare, Larry Ellingsworth
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0210749 (2019)
PLoS ONE
PLoS ONE
Globally, human respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections in newborns, young children, and the elderly for which there is no vaccine. The RSV fusion (F) glycoprotein is a major target for vaccine devel
Publikováno v:
Proceedings of the National Academy of Sciences. 112:12687-12692
Leiomodin (Lmod) is a class of potent tandem-G-actin-binding nucleators in muscle cells. Lmod mutations, deletion, or instability are linked to lethal nemaline myopathy. However, the lack of high-resolution structures of Lmod nucleators in action sev