Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Fengyi Wan"'
Autor:
Huimin Yu, Zixin Zhang, Gangping Li, Yan Feng, Lingling Xian, Fatemeh Bakhsh, Dongqing Xu, Cheng Xu, Tyrus Vong, Bin Wu, Florin M. Selaru, Fengyi Wan, Mark Donowitz, G. William Wong
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 4, Pp 1000-1015 (2023)
Background & Aims: The adipokine CTRP3 has anti-inflammatory effects in several nonintestinal disorders. Although serum CTRP3 is reduced in patients with inflammatory bowel disease (IBD), its function in IBD has not been established. Here, we elucida
Externí odkaz:
https://doaj.org/article/387ac2fa670e4b77a63d9130180641ca
Autor:
Cuiping Zhang, Xiaojing Cui, Yi Liu, Fang Wang, Robert Signer, Kapana Nattamai, Daohong Zhou, Yi Zheng, Hartmut Geiger, Fengyi Wan, Ying Liang
Publikováno v:
Haematologica, Vol 108, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/7306213419db47d5a4b95623dd5f3604
Publikováno v:
Cancer Medicine, Vol 8, Iss 13, Pp 6106-6113 (2019)
Abstract Although targeting DNA repair signaling pathways has emerged as a promising therapeutic for skin cancer, the relevance of DNA damage responses (DDR) in the development and survival of nonmelanoma skin cancer (NMSC), the most common type of s
Externí odkaz:
https://doaj.org/article/bc640f62a4154d80a4ebc0fc4a3684e6
Autor:
Laxmi Sunuwar, Azra Frkatović, Sodbo Sharapov, Qinchuan Wang, Heather M. Neu, Xinqun Wu, Talin Haritunians, Fengyi Wan, Sarah Michel, Shaoguang Wu, Mark Donowitz, Dermot McGovern, Gordan Lauc, Cynthia Sears, Joanna Melia
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
ZIP8 is a metal transporter with a role in manganese (Mn) homeostasis. A common genetic variant in ZIP8 (rs13107325; A391T) ranks in the top 10 of pleiotropic SNPs identified in GWAS; A391T has associations with an increased risk of schizophrenia, ob
Externí odkaz:
https://doaj.org/article/c8a8d7250ef44726afdebb8c100fb512
Autor:
Xue Xia, Yue Liu, Andrea Hodgson, Dongqing Xu, Wenxuan Guo, Hongbing Yu, Weifeng She, Chenxing Zhou, Lei Lan, Kai Fu, Bruce A Vallance, Fengyi Wan
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007898 (2019)
Attaching/Effacing (A/E) bacteria include human pathogens enteropathogenic Escherichia coli (EPEC), enterohemorrhagic E. coli (EHEC), and their murine equivalent Citrobacter rodentium (CR), of which EPEC and EHEC are important causative agents of foo
Externí odkaz:
https://doaj.org/article/3998c08814ba41c4afc823c4cc8e2e8f
Publikováno v:
Antibodies, Vol 3, Iss 1, Pp 37-55 (2014)
ADP-ribosylation is an essential post-translational modification, mediated by a family of proteins named poly-ADP-ribose polymerases/Diphtheria toxin-like ADP-ribosyltransferases (PARPs/ARTDs), that functions to assist in cellular homeostasis through
Externí odkaz:
https://doaj.org/article/a4280234614543b1aca6d7d52d666beb
Publikováno v:
eLife, Vol 5 (2016)
Previously we reported that Src-associated-substrate-during-mitosis-of-68kDa (Sam68/KHDRBS1) is pivotal for DNA damage-stimulated NF-κB transactivation of anti-apoptotic genes (Fu et al., 2016). Here we show that Sam68 is critical for genotoxic stre
Externí odkaz:
https://doaj.org/article/80f8382ad84040fb9bf01450802df992
Autor:
Xin Sun, Kai Fu, Andrea Hodgson, Eric M Wier, Matthew G Wen, Olena Kamenyeva, Xue Xia, Lily Y Koo, Fengyi Wan
Publikováno v:
PLoS Biology, Vol 14, Iss 9, p e1002543 (2016)
The rapid and robust synthesis of polymers of adenosine diphosphate (ADP)-ribose (PAR) chains, primarily catalyzed by poly(ADP-ribose) polymerase 1 (PARP1), is crucial for cellular responses to DNA damage. However, the precise mechanisms through whic
Externí odkaz:
https://doaj.org/article/76de77ae96684d6a973ec53107381128
Publikováno v:
eLife, Vol 5 (2016)
Nuclear factor kappa B (NF-κB)-mediated transcription is an important mediator for cellular responses to DNA damage. Genotoxic agents trigger a 'nuclear-to-cytoplasmic' NF-κB activation signaling pathway; however, the early nuclear signaling cascad
Externí odkaz:
https://doaj.org/article/611381bba30b4a869c74157cc791d44b
Autor:
Lei Gao, Dantong Li, Ke Ma, Wenjuan Zhang, Tao Xu, Cong Fu, Changbin Jing, Xiaoe Jia, Shuang Wu, Xin Sun, Mei Dong, Min Deng, Yi Chen, Wenge Zhu, Jinrong Peng, Fengyi Wan, Yi Zhou, Leonard I Zon, Weijun Pan
Publikováno v:
PLoS Genetics, Vol 11, Iss 7, p e1005346 (2015)
In vertebrate definitive hematopoiesis, nascent hematopoietic stem/progenitor cells (HSPCs) migrate to and reside in proliferative hematopoietic microenvironment for transitory expansion. In this process, well-established DNA damage response pathways
Externí odkaz:
https://doaj.org/article/f70cc9a8bf37471bb44d437421550617