Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Fengxue Geng"'
Publikováno v:
Journal of Oral Microbiology, Vol 16, Iss 1 (2024)
ABSTRACTObjectives This study aims to clarify the effect of ferroptosis by P. gingivalis on periodontal epithelium impairment and potential mechanisms.Materials and methods The expression of epithelial junction proteins (CDH1, OCLN, ZO-1), FTL and GP
Externí odkaz:
https://doaj.org/article/fd3759e0b4e64222966479862f14dacc
Autor:
Nan Feng, Xuan Han, Da Peng, Fengxue Geng, Qian Li, Chunlin Pan, Hongyan Wang, Yaping Pan, Lisi Tan
Publikováno v:
Journal of Oral Microbiology, Vol 16, Iss 1 (2024)
ABSTRACTBackground Epidemiological evidence has confirmed that periodontitis is an essential and independent risk factor of chronic obstructive pulmonary disease (COPD). Porphyromonas gingivalis, a major pathogen implicated in periodontitis, may make
Externí odkaz:
https://doaj.org/article/629d1d1dea8d49bb8c888e5225879657
Publikováno v:
Journal of Oral Microbiology, Vol 14, Iss 1 (2022)
Necroptosis, a new type of regulated cell death with massive release of damage-associated molecular patterns (DAMPs), is involved in the pathogenesis of periodontitis. However, the role of necroptosis in oral epithelial cells and the following effect
Externí odkaz:
https://doaj.org/article/289e9adb8f164c3ca5a888c991ecfaaa
Publikováno v:
PeerJ, Vol 10, p e12991 (2022)
Background Oral squamous cell carcinoma (OSCC), the most common type of primary malignant tumor in the oral cavity, is a lethal disease with high recurrence and mortality rates. Butyrate, a metabolite produced by periodontal pathogens, has been linke
Externí odkaz:
https://doaj.org/article/fac162aa6114495eb17daa93eec483b9
Autor:
Xue Yang, Li Niu, Yaping Pan, Xianghui Feng, Jie Liu, Yan Guo, Chunling Pan, Fengxue Geng, Xiaolin Tang
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Porphyromonas gingivalis (P. gingivalis), one of the most important pathogens of periodontitis, is closely associated with the aggravation and recurrence of periodontitis and systemic diseases. Antibacterial peptide LL-37, transcribed from the cathel
Externí odkaz:
https://doaj.org/article/a2330e37488b408cb8f3bf13ed843d2b
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Recent investigations revealed the relationship between chronic periodontitis, Porphyromonas gingivalis and cancer. However, host genes that change in response to chronic infection with P. gingivalis and may contribute to oral cancer have remained la
Externí odkaz:
https://doaj.org/article/60a456854822418ba668fdc23c49457c
Autor:
Yaping Pan, Shuwei Zhang, Yuchao Li, Junchao Liu, Chen Li, Fengxue Geng, Qian Li, Zhiying Zhang
Publikováno v:
Journal of Cellular and Molecular Medicine
Accumulating evidence links Fusobacterium nucleatum with tumorigenesis. Our previous study demonstrated that F. nucleatum infection can induce epithelial‐mesenchymal transition (EMT) in oral epithelial cells and elaborated a probable signal pathway
Publikováno v:
The Febs Journal
Fusobacterium nucleatum, an anaerobic oral opportunistic pathogen associated with periodontitis, has been considered to be associated with the development of oral squamous cell carcinoma (OSCC). However, the initial host molecular alterations induced
Publikováno v:
DNA and Cell Biology
Bacterial infection influences genomic stability and integrity by causing DNA damage, which increases the possibility of tumor initiation and development. We aimed to investigate whether Fusobacterium nucleatum, one of the periodontal pathogens, prom
Autor:
Li Niu, Jingbo Liu, Xiaolin Tang, Chunliang Ma, Fengxue Geng, Xinyue Hu, Hongyan Wang, Qian Li, Xue Yang, Yuehua Huang, Chunling Pan, Yakun Shi
Publikováno v:
Journal of Periodontology. 91:956-966
Background The present study aimed to explore the effects of the active form of vitamin D (calcitriol, 1α,25-dihydroxyvitamin D3 , 1α,25 (OH)2 D3 , 1,25D) on live Porphyromonas gingivalis internalized into KB cells and U937 cells. Methods Quantitat