Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Fengqing Lu"'
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Advances in neuroimaging techniques during the past few decades have captured impaired functional brain activity in migraine disorders, yet the molecular mechanisms accounting for its alterations in migraine remain largely unknown. A total of 27 pati
Externí odkaz:
https://doaj.org/article/d32f5077e304418aa42334fba5ee7f07
Autor:
Hong Zhu, Jin Qian, Wenqiu Wang, Quan Yan, Ying Xu, Yuan Jiang, Lei Zhang, Fengqing Lu, Weiting Hu, Xi Zhang, Fenghua Wang, Xiaodong Sun
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59339 (2013)
BACKGROUND: Apoptosis of photoreceptors plays a critical role in the vision loss caused by retinal detachment (RD). Pharmacologic inhibition of photoreceptor cell death may prevent RD. This study investigated the role of GADD153 that participates in
Externí odkaz:
https://doaj.org/article/ec9ca48d3d344adbb3bd0b4402c37c17
Publikováno v:
Current Pharmaceutical Design. 27:1847-1855
Enhancer-promoter interactions (EPIs) in the human genome are of great significance to transcriptional regulation, which tightly controls gene expression. Identification of EPIs can help us better decipher gene regulation and understand disease mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3de19d5122e2218e19f65a5db40fa5
https://doi.org/10.2174/1381612826666201124112710
https://doi.org/10.2174/1381612826666201124112710
Publikováno v:
Briefings in Bioinformatics. 22
Artificial intelligence, such as deep generative methods, represents a promising solution to de novo design of molecules with the desired properties. However, generating new molecules with biological activities toward two specific targets remains an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a517fc69709ccb4bdc2816e043ec9e4a
https://doi.org/10.1093/bib/bbab333
https://doi.org/10.1093/bib/bbab333
Autor:
Gang Han, Shihou Sheng, Jun Wei, Tao Zhang, Guangjun Xu, Yahong Chen, Shijie Li, Tongjun Liu, Huiqiu Yu, Fengqing Lu, Jinghui Yang, Tianhong Sun, Yongchao Li
Publikováno v:
RSC Advances. 5:53846-53856
A traditional Chinese medicine cantharidin which was previously found to be effective on colorectal cancer cells was translated into nanoparticles for drug delivery to reduce its side effects and enhance its drug efficacy. By further introducing the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a2b5dbe2d1b26bed8beed136a74eae8
https://doi.org/10.1039/c5ra08154h
https://doi.org/10.1039/c5ra08154h
Autor:
Lei, Zhang, Fenghua, Wang, Yuan, Jiang, Shan, Xu, Fengqing, Lu, Wenqiu, Wang, Xiangjun, Sun, Xiaodong, Sun
Publikováno v:
Frontiers in Bioscience. :661-671
Abnormal migration of retinal pigment epithelium (RPE) contributes to a variety of disorders such as proliferative vitreoretinopathy. Here, the effect of epidermal growth factor (EGF), and signaling by its receptor (ERGR)/phosphatidylinositol 3-kinas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237705f6f39652d678f62a608cb997a5
https://doi.org/10.2741/s398
https://doi.org/10.2741/s398
Publikováno v:
Regenerative Medicine. 7:663-673
Aim: To identify human hair cell progenitors from adult inner ear sensory epithelium. Materials & methods: We collected discarded utricles from translabyrinthine surgery and isolated human utricular sensory epithelial cells (HUCs) to explore whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b969d180a07042f3fee2d76cf63fe5
https://doi.org/10.2217/rme.12.53
https://doi.org/10.2217/rme.12.53
Autor:
Xiaodong Sun, Ying Wu, Weiting Hu, Yuan Jiang, Hong Wang, Suqin Yu, Fei-ping Xu, Xun Xu, Wenqiu Wang, Fengqing Lu, Weijun Wang, Fenghua Wang
Publikováno v:
Retina. 32:679-686
To evaluate the morphology and functional recovery of the retina after treatment of idiopathic choroidal neovascularization using intravitreal injections of bevacizumab in young adults.For this interventional case series, 20 eyes of 19 patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bcdf0fd4f5a22750ab6d72a9cf26bb5
https://doi.org/10.1097/iae.0b013e318227ab24
https://doi.org/10.1097/iae.0b013e318227ab24
Autor:
Weiting Hu, Xiaodong Sun, Quan Yan, Ying Xu, Lei Zhang, Xi Zhang, Fenghua Wang, Yuan Jiang, Jin Qian, Wenqiu Wang, Hong Zhu, Fengqing Lu
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59339 (2013)
PLoS ONE
PLoS ONE
BACKGROUND: Apoptosis of photoreceptors plays a critical role in the vision loss caused by retinal detachment (RD). Pharmacologic inhibition of photoreceptor cell death may prevent RD. This study investigated the role of GADD153 that participates in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b0d719fd9cf4c02df2d03134616bf9
https://doi.org/10.1371/journal.pone.0059339
https://doi.org/10.1371/journal.pone.0059339
Autor:
Qing Gu, Xiaodong Sun, Jiannan Huang, Fengqing Lu, Fenghua Wang, Shan Xu, Weiting Hu, Wenqiu Wang
Publikováno v:
Investigative Opthalmology & Visual Science. 52:7213
Purpose Integrin α5β1 is involved in the development of choroidal neovascularization (CNV). Thus, the inhibition of integrin α5β1 may provide an alternative to the current standard of CNV therapy, which involves inhibition of vascular endothelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac1c950e42768f8c8f64ce1fe07cf98
https://doi.org/10.1167/iovs.10-7097
https://doi.org/10.1167/iovs.10-7097