Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Fengqin Fang"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract The lncRNA NEAT1 has been shown to promote the progression of several cancers, containing laryngeal squamous cell carcinoma (LSCC). However, the precise mechanism by which it promotes LSCC progression remains unclear. In this study, we verif
Externí odkaz:
https://doaj.org/article/9bb1a2667d494bb68d2fd62e11ba4153
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Unaffordable medical treatment and inflated drug prices have become a challenging issue for lawmakers worldwide. To reduce the financial burden and standardize the pharmaceutical market, the Chinese government has issued several detailed regulations,
Externí odkaz:
https://doaj.org/article/05292d491c764618936fd1dfc4424121
Autor:
Zhenkun Mao, Jinxiu Chen, Dandan Jiang, Ningmin Zhao, Yinhui Qin, Xiangju Mao, Fengqin Fang, Peizhi Ma
Publikováno v:
ACS Omega, Vol 9, Iss 1, Pp 1554-1561 (2023)
Externí odkaz:
https://doaj.org/article/7e0614253c564185b4ebdad9d3dbf7dc
Autor:
Wenqiang Cao, Ines Sturmlechner, Huimin Zhang, Jun Jin, Bin Hu, Rohit R. Jadhav, Fengqin Fang, Cornelia M. Weyand, Jörg J. Goronzy
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112195- (2023)
Summary: Naive CD4+ T cells are more resistant to age-related loss than naive CD8+ T cells, suggesting mechanisms that preferentially protect naive CD4+ T cells during aging. Here, we show that TRIB2 is more abundant in naive CD4+ than CD8+ T cells a
Externí odkaz:
https://doaj.org/article/ecfd1197fa604b269269d40f24f8721e
Autor:
Fengqin Fang, Wenqiang Cao, Yunmei Mu, Hirohisa Okuyama, Lingjie Li, Jingtao Qiu, Cornelia M. Weyand, Jörg J. Goronzy
Publikováno v:
JCI Insight, Vol 7, Iss 12 (2022)
The ectonucleotidase CD39 functions as a checkpoint in purinergic signaling on effector T cells. By depleting eATP and initiating the generation of adenosine, it impairs memory cell development and contributes to T cell exhaustion, thereby causing de
Externí odkaz:
https://doaj.org/article/9d5e1c41942241ca89dad326c17def65
Publikováno v:
Brazilian Journal of Otorhinolaryngology, Vol 86, Iss 4, Pp 502-512 (2020)
Introduction: Stomal recurrence is a troublesome complication after total laryngectomy. Despite a large number of studies having been performed, there is still controversy about which risk factors are most significant for the development of stomal re
Externí odkaz:
https://doaj.org/article/01e345b7c9644888a9bfb481e2ef7e13
Publikováno v:
Brazilian Journal of Otorhinolaryngology, Vol 84, Iss 4, Pp 416-425 (2018)
Introduction: Reconstruction with a free flap is routine in head and neck surgery because of better functional outcomes, improved esthetics, and generally higher success rates. Objective: To evaluate the clinical outcomes in patients undergoing diffe
Externí odkaz:
https://doaj.org/article/b4cba46ff496420cb716dee61804e093
Autor:
Fengqin Fang, Mingcan Yu, Mary M. Cavanagh, Jessica Hutter Saunders, Qian Qi, Zhongde Ye, Sabine Le Saux, William Sultan, Emerson Turgano, Cornelia L. Dekker, Lu Tian, Cornelia M. Weyand, Jörg J. Goronzy
Publikováno v:
Cell Reports, Vol 14, Iss 5, Pp 1218-1231 (2016)
Summary: In an immune response, CD4+ T cells expand into effector T cells and then contract to survive as long-lived memory cells. To identify age-associated defects in memory cell formation, we profiled activated CD4+ T cells and found an increased
Externí odkaz:
https://doaj.org/article/c6d5eafc2bd946109c7b4953a251f2c2
Autor:
Lingjie Li, Bo Liu, Orly L. Wapinski, Miao-Chih Tsai, Kun Qu, Jiajing Zhang, Jeff C. Carlson, Meihong Lin, Fengqin Fang, Rajnish A. Gupta, Jill A. Helms, Howard Y. Chang
Publikováno v:
Cell Reports, Vol 5, Iss 1, Pp 3-12 (2013)
Long noncoding RNAs (lncRNAs) are thought to be prevalent regulators of gene expression, but the consequences of lncRNA inactivation in vivo are mostly unknown. Here, we show that targeted deletion of mouse Hotair lncRNA leads to derepression of hund
Externí odkaz:
https://doaj.org/article/7359618d83a74bfbb5b1213b1a654797
Publikováno v:
In Brazilian Journal of Otorhinolaryngology September-October 2023 89(5)