Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Fengling, Shao"'
Causal association of plasma circulating metabolites with nephritis: a Mendelian randomization study
Autor:
Fengling Shao, Yingling Yao, Dunchu Weng, Runzhi Wang, Ruiling Liu, Yongjia Zhang, Erhan Li, Mengdi Wang, Yuewu Tang, Yubin Ding, Yajun Xie
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundNephritis is a pivotal catalyst in chronic kidney disease (CKD) progression. Although epidemiological studies have explored the impact of plasma circulating metabolites and drugs on nephritis, few have harnessed genetic methodologies to est
Externí odkaz:
https://doaj.org/article/e3f527e0d5b548beb917e9c3d524790a
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract 3-Hydroxymethylglutaryl-CoA synthase 2 (HMGCS2) is the rate-limiting enzyme for ketone body synthesis, and most current studies focus on mitochondrial maturation and metabolic reprogramming. The role of HMGCS2 was evaluated in a pan-cancer m
Externí odkaz:
https://doaj.org/article/7612ea7de40e47ddb019c6dfeeb63064
Autor:
Qingqing Liu, Zhenni Wang, Yan Jiang, Fengling Shao, Yue Ma, Mingzhao Zhu, Qing Luo, Yang Bi, Lijian Cao, Liang Peng, Jianwu Zhou, Zhenzhen Zhao, Xiaobin Deng, Tong-Chuan He, Shan Wang
Publikováno v:
Genes and Diseases, Vol 9, Iss 6, Pp 1624-1638 (2022)
Neuroblastoma (NB), which is the most common pediatric extracranial solid tumor, varies widely in its clinical presentation and outcome. NB has a unique ability to spontaneously differentiate and regress, suggesting a potential direction for therapeu
Externí odkaz:
https://doaj.org/article/91cc71e6713a429787d34c44d725bf93
Autor:
Lijian Cao, Qingqing Liu, Yue Ma, Fengling Shao, Zhenzhen Zhao, Xiaobin Deng, Jianwu Zhou, Shan Wang
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
ObjectiveNeuroblastoma (NB), originating from sympathetic spinal tissue, is a serious threat to the life of children. Especially in the high-risk group, an overall five-year survival rate less than 50% indicates an extremely poor clinical outcome. He
Externí odkaz:
https://doaj.org/article/885ab466ef28488b95236e46185beb12
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundLung adenocarcinoma (LUAD) is the most common respiratory globallywith a poor prognosis. Lipid metabolism is extremely important for the occurrence and development of cancer. However, the role of genes involved in lipid metabolism in LUAD d
Externí odkaz:
https://doaj.org/article/bfdaa2140804425488fbc24335839851
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-10 (2021)
Abstract Background Osteosarcoma is a highly malignant and common bone tumour with an aggressive disease course and a poor prognosis. Previous studies have demonstrated the relationship between long noncoding RNAs (lncRNAs) and tumorigenesis, metasta
Externí odkaz:
https://doaj.org/article/f8ce846a151c4354a4189a0374af9303
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8489
The chromodomain helicase DNA binding domain 5 (CHD5) is required for neural development and plays an important role in the regulation of gene expression. Although CHD5 exerts a broad tumor suppressor effect in many tumor types, its specific function
Publikováno v:
DNA and Cell Biology. 40:332-347
Neuroblastoma (NB) has the highest incidence of all extracranial solid tumors in children and is highly lethal. This study aims to establish a prognostic model of NB with MYCN-related genes. We determined the gene expression profiles of 900 NB sample
Publikováno v:
BMC Medical Genomics
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-10 (2021)
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-10 (2021)
Background Osteosarcoma is a highly malignant and common bone tumour with an aggressive disease course and a poor prognosis. Previous studies have demonstrated the relationship between long noncoding RNAs (lncRNAs) and tumorigenesis, metastasis, and
Publikováno v:
DNA and cell biology. 40(2)
Neuroblastoma (NB) has the highest incidence of all extracranial solid tumors in children and is highly lethal. This study aims to establish a prognostic model of NB with