Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fengkun Guan"'
Autor:
Jiazhen Wu, Fengkun Guan, Haipiao Huang, Hanbin Chen, Yuhong Liu, Shangbin Zhang, Muxia Li, Jianping Chen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 178, Iss , Pp 117297- (2024)
Purpose: To investigate the therapeutic effect and underlying mechanism of tetrahydrocurcumin (THC) on nonalcoholic steatohepatitis (NASH) induced by high-fat diet (HFD). Methods: NASH rat model was established through long-term feeding HFD, and the
Externí odkaz:
https://doaj.org/article/944d8a9f5bce4fc2b18e1329a66ae3c7
Autor:
Jiazhen Wu, Yuxuan Gan, Huijuan Luo, Nan Xu, Liping Chen, Mengyao Li, Fengkun Guan, Ziren Su, Zhixiu Lin, Jianhui Xie, Yuhong Liu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Intestinal mucositis (IM) is the main side effect observed in patients who receive cancer chemotherapy. The characteristics of ulceration, vomiting, and severe diarrhea cause patients to delay or abandon further treatment, thereby aggravating their p
Externí odkaz:
https://doaj.org/article/84fd3027760b4a9a936eb0e5a544d1a5
Autor:
Nan Xu, Huijuan Luo, Minyao Li, Jiazhen Wu, Xue Wu, Liping Chen, Yuxuan Gan, Fengkun Guan, Mengyao Li, Ziren Su, Jiannan Chen, Yuhong Liu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 134, Iss , Pp 111104- (2021)
Non-alcoholic fatty liver disease (NAFLD) has been a leading cause of chronic metabolic disease, seriously posing healthy burdens to the public, whereas interventions available for it are limited to date. Patchouli oil had been reported to attenuate
Externí odkaz:
https://doaj.org/article/6393bb851b15482db17f2c0fb46ca113
Autor:
Juanjuan Cheng, Lieqiang Xu, Qiuxia Yu, Guoshu Lin, Xingdong Ma, Mengyao Li, Fengkun Guan, Yuhong Liu, Xiaoqi Huang, Jianhui Xie, Jiannan Chen, Ziren Su, Yucui Li
Publikováno v:
European journal of pharmacology. 933
Nutrient excess caused by excessive fructose intake can lead to insulin resistance and dyslipidemia, which further causes the development of metabolic syndrome. Metformin is a well-known AMPK activator widely used for the treatment of metabolic syndr
Autor:
Juanjuan Cheng, Xingdong Ma, Guangtao Yan, Qiuxia Yu, Zhen Huang, Guoshu Lin, Mengyao Li, Fengkun Guan, Ziren Su, Fang Yan, Yuhong Liu, Qingfeng Xie
Publikováno v:
Food and Chemical Toxicology. 175:113731
Autor:
Fengkun, Guan, Huijuan, Luo, Jiazhen, Wu, Mengyao, Li, Liping, Chen, Ning, Huang, Guilan, Wei, Juan, Nie, Baoyi, Chen, Ziren, Su, Xie, Zhang, Yuhong, Liu
Publikováno v:
International Immunopharmacology. 110:109007
Ulcerative colitis (UC), an inflammatory disease, is widely thought to be associated with colonic barrier damage and inflammatory response. With the destruction of the colonic barrier, lipopolysaccharide (LPS) enters the liver through the portal vein
Autor:
Jia-Zhen Wu, Jian-Nan Chen, Yuxuan Gan, Yu-Cui Li, Liping Chen, Yu-Hong Liu, Mengyao Li, Nan Xu, Fengkun Guan, Zi-Ren Su, Huijuan Luo
Publikováno v:
International immunopharmacology. 98
Non-alcoholic steatohepatitis (NASH), an extreme progressive subtype of metabolic associated fatty liver disease, is well characterized by hepatic steatosis, injury and inflammation. It causes irreversible hepatic damage and there are no approved int
Autor:
Minyao Li, Yuxuan Gan, Yu-Hong Liu, Mengyao Li, Xue Wu, Fengkun Guan, Jia-Zhen Wu, Zi-Ren Su, Nan Xu, Huijuan Luo, Liping Chen, Jian-Nan Chen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 134, Iss, Pp 111104-(2021)
Non-alcoholic fatty liver disease (NAFLD) has been a leading cause of chronic metabolic disease, seriously posing healthy burdens to the public, whereas interventions available for it are limited to date. Patchouli oil had been reported to attenuate
Autor:
Xue Wu, Yu-Hong Liu, Yuxuan Gan, Huijuan Luo, Liping Chen, Minyao Li, Yu-Cui Li, Jia-Zhen Wu, Zi-Ren Su, Nan Xu, Jian-Nan Chen, Fengkun Guan
Publikováno v:
Biochemical Pharmacology. 182:114260
Ulcerative colitis (UC) often occurs accompanied by colonic leakage and flora imbalance, resulting in secondary liver injury (SLI). SLI, in turn, aggravates UC, so the treatment of UC should not ignore it. β-patchoulene (β-PAE), a tricyclic sesquit