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Akademický článek

Solid lipid nanoparticle as an effective drug delivery system of a novel curcumin derivative: formulation, release in vitro and pharmacokinetics in vivo

Autor: Wenmei Zhao, Mingtang Zeng, Ke Li, Chao Pi, Zerong Liu, Chenglin Zhan, Jiyuan Yuan, Zhilian Su, Yuxun Wei, Jie Wen, Fengjuan Pi, Xinjie Song, Robert J. Lee, Yumeng Wei, Ling Zhao

Publikováno v: Pharmaceutical Biology, Vol 60, Iss 1, Pp 2300-2307 (2022)

Context Curcumin (Cur) has a short duration of action which limits its therapeutic efficacy. Carbonic acid 17-(1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 4-[7-(4-hydrox

Externí odkaz: https://doaj.org/article/e815240fb8f945899d4561832770e0de

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Akademický článek

Bone-targeting drug delivery system of biomineral-binding liposomes loaded with icariin enhances the treatment for osteoporosis

Autor: Xiaoduan Sun, Jun Wei, Jiayao Lyu, Tierong Bian, Zhongbing Liu, Juan Huang, Fengjuan Pi, Chunhong Li, Zhirong Zhong

Publikováno v: Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-16 (2019)

Abstract Background Osteoporosis is a bone-incapacitating malady and it is characterized by obvious bone mass loss and bone microarchitecture deterioration. Current treatments for osteoporosis have many limitations, including the non-obvious therapeu

Externí odkaz: https://doaj.org/article/556fd6e6399640cba61797697a0e51d4

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Solid lipid nanoparticle as an effective drug delivery system of a novel curcumin derivative: formulation, release

Autor: Wenmei, Zhao, Mingtang, Zeng, Ke, Li, Chao, Pi, Zerong, Liu, Chenglin, Zhan, Jiyuan, Yuan, Zhilian, Su, Yuxun, Wei, Jie, Wen, Fengjuan, Pi, Xinjie, Song, Robert J, Lee, Yumeng, Wei, Ling, Zhao

Publikováno v: Pharmaceutical biology. 60(1)

Curcumin (Cur) has a short duration of action which limits its therapeutic efficacy. Carbonic acid 17-(1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 4-[7-(4-hydroxy-3-meth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b9b26316264e643a669fd353d0946e48
https://pubmed.ncbi.nlm.nih.gov/36606719

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MOESM1 of Bone-targeting drug delivery system of biomineral-binding liposomes loaded with icariin enhances the treatment for osteoporosis

Autor: Xiaoduan Sun, Wei, Jun, Jiayao Lyu, Tierong Bian, Zhongbing Liu, Huang, Juan, Fengjuan Pi, Chunhong Li, Zhirong Zhong

Additional file 1. Synthesis of biomineral-binding lipid of PPi-TEG-Chol and pharmacokinetics evaluation of BBL in Rats. Figure S1. Mean plasma concentration-time profile of icariin in rats after intraperitoneal administration. Figures S2â S5. 1H NM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab6795ef6c07f5f5b50f9dffde5c2dd

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Bone-targeting drug delivery system of biomineral-binding liposomes loaded with icariin enhances the treatment for osteoporosis

Autor: Jun Wei, Zhirong Zhong, Zhongbing Liu, Xiaoduan Sun, Tierong Bian, Juan Huang, Jiayao Lyu, Chunhong Li, Fengjuan Pi

Publikováno v: Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-16 (2019)

Background Osteoporosis is a bone-incapacitating malady and it is characterized by obvious bone mass loss and bone microarchitecture deterioration. Current treatments for osteoporosis have many limitations, including the non-obvious therapeutic effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e07752efc8e7c1a4e663313e49549af
http://europepmc.org/articles/PMC6341739

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[Mathematic modeling and experimental validation of macrostate quality expression for multicomponent in Chinese materia medica]

Autor: Fuyuan, He, Kaiwen, Deng, Jilian, Shi, Wenlong, Liu, Fengjuan, Pi

Publikováno v: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 36(22)

To establish the unitive multicomponent quality system bridged macrostate mathematic model parameters of material quality and microstate component concentration for Chinese materia medica (CMM).According to law of biologic laws of thermodynamics, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9039eb1acc0e6f06a076500213261f76
https://pubmed.ncbi.nlm.nih.gov/22375386

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Mathematic modeling and experimental validation of macrostate quality expression for multicomponent in Chinese materia medica

Autor: Fengjuan Pi, Wen-Long Liu, Kai-Wen Deng, Fu-Yuan He, Ji-Lian Shi

Publikováno v: China Journal of Chinese Materia Medica.

OBJECTIVE To establish the unitive multicomponent quality system bridged macrostate mathematic model parameters of material quality and microstate component concentration for Chinese materia medica (CMM). METHOD According to law of biologic laws of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6526ab364d3b0c53254521e9a2dd4bcb
https://doi.org/10.4268/cjcmm20112208

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Theoretical and experimental studies on apparent solubility parameters of multiple components for Chinese materia medica with HPLC fingerprint

Autor: Kai-Wen Deng, Wen-Long Liu, Fu-Yuan He, Ruwen Dai, Fengjuan Pi, Hong-Hao Zhou, Jin Fu, Dezhi Wu, Jie-Ying Luo

Publikováno v: China Journal of Chinese Matera Medica. 35

Objective To establish the theories and methods to determine apparent solubility paraneters of multiple components for the Chinese materia medica (CMM) with HPLC fingerprint. Method The mathematical functional expresses to determine the apparent solu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c10b4c31763362c89bef1487b2fbd1
https://doi.org/10.4268/cjcmm20100808

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