Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Fengjuan Huang"'
Autor:
Qinrui Wu, Fengjuan Huang
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
AbstractDiabetic nephropathy (DN) is a severe complication of diabetes mellitus, causing a substantive threat to the public, which receives global concern. However, there are limited drugs targeting the treatment of DN. Owing to this, it is highly cr
Externí odkaz:
https://doaj.org/article/744f3009924f4e9dab5f90707f63a6cf
Autor:
Tongyue Yang, Qi Feng, Mingwei Shao, Mengxing Pan, Feng Guo, Yi Song, Fengjuan Huang, Zhao Linlin, Jiao Wang, Lina Wu, Guijun Qin, Yanyan Zhao
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Diabetic kidney disease (DKD) is characterized by complex pathogenesis and poor prognosis; therefore, an exploration of novel etiological factors may be beneficial. Despite glycemic control, the persistence of transient hyperglycemia still induces va
Externí odkaz:
https://doaj.org/article/7ca61470a6764da0859fd66d9516d88b
Autor:
Qinrui Wu, Fengjuan Huang
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Diabetic kidney disease (DKD), one of the most severe complications of diabetes mellitus (DM), has received considerable attention owing to its increasing prevalence and contribution to chronic kidney disease (CKD) and end-stage kidney disease (ESRD)
Externí odkaz:
https://doaj.org/article/ae3d58ef0f7e45a9ace7fb5e5c1c01d2
Autor:
Na Jing, Mengxing Pan, Yi Song, Feng Guo, Haohao Zhang, Jiao Wang, Zhe Cao, Shiyu Liu, Lina Wu, Hongfei Ji, Fengjuan Huang, Xiaoxu Ding, Chang Qi, Sen Huang, Xinyu Yang, Li Zhang, Chunhua Song, Guijun Qin, Yanyan Zhao
Publikováno v:
Therapeutic Advances in Chronic Disease, Vol 12 (2021)
Aim: To evaluate the renal outcomes and prognostic factors among patients with type-2 diabetes (T2D) and biopsy-confirmed diabetic nephropathy (DN), non-diabetic renal disease (NDRD) and DN mixed with NDRD (MIX). Design and Methods: Patients with bot
Externí odkaz:
https://doaj.org/article/def5d597edb943729c549c6001a91554
Autor:
Fengjuan Huang, Qingzhu Wang, Feng Guo, Yanyan Zhao, Linlin Ji, Tingting An, Yi Song, Yang Liu, Yanyan He, Guijun Qin
Publikováno v:
EBioMedicine, Vol 48, Iss , Pp 491-504 (2019)
Background: Tubulointerstitial fibrosis (TIF) plays an important role in the progression of diabetic kidney disease (DKD). Forkhead box O1 (FoxO1) is involved in the regulation of metabolism and cell apoptosis, but its function in renal TIF induced b
Externí odkaz:
https://doaj.org/article/5edf037ee2e94d4f80c91447c09c2323
Autor:
Yang Liu, Yanyan He, Qingzhu Wang, Feng Guo, Fengjuan Huang, Linlin Ji, Tingting An, Guijun Qin
Publikováno v:
Journal of Diabetes Investigation, Vol 10, Iss 2, Pp 261-271 (2019)
Abstract Aims/Introduction Vitamin D3 deficiency can lead to male hypogonadism in diabetes mellitus, but the target organs and the mechanism driving the disorder are unclear. This experiment was designed to study the relationship between vitamin D3 d
Externí odkaz:
https://doaj.org/article/6ee2b571ffd34dbd9cb5a7dc603bc5f1
Autor:
Fengjuan Huang, Yanyan Zhao, Qingzhu Wang, Jan-Luuk Hillebrands, Jacob van den Born, Linlin Ji, Tingting An, Guijun Qin
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Tubulointerstitial fibrosis (TIF) plays an important role in the progression of renal fibrosis in diabetic nephropathy (DN). Accumulating evidence supports a crucial inhibitory effect of dapagliflozin, a SGLT2 inhibitor, on TIF, but the underlying me
Externí odkaz:
https://doaj.org/article/106e4d249d504282a26632d12c8e54bb
Autor:
Yanyan He, Yang Liu, Qing-Zhu Wang, Feng Guo, Fengjuan Huang, Linlin Ji, Tingting An, Guijun Qin
Publikováno v:
Journal of Diabetes Research, Vol 2019 (2019)
Objective. In diabetes mellitus, vitamin D3 deficiency affects sex hormone levels and male fertility; however, the mechanism leading to the disorder is unclear. This research was designed to investigate the mechanism of vitamin D3 deficiency and hypo
Externí odkaz:
https://doaj.org/article/d5581ddc58a94533afbb197dbb697cd9
Autor:
Wenci Gong, Fengjuan Huang, Lei Sun, Aiping Yu, Xiaofan Zhang, Yuxin Xu, Yujuan Shen, Jianping Cao
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 12, p e0007000 (2018)
Schistosomiasis is endemic to many regions of the world and affects approximately 200 million people. Conventional adaptive T cell responses are considered to be the primary contributors to the pathogenesis of Schistosoma japonicum infection, leading
Externí odkaz:
https://doaj.org/article/6d147c82ef7d4c6c868bdc7337f2a926
Autor:
Wenci Gong, Fengjuan Huang, Yilei Ma, Hongmei Bai, Lan Yin, Jun Li, Chunxia Chen, Xindong Xu, Xiao-Ping Chen
Publikováno v:
Parasites & Vectors, Vol 8, Iss 1, Pp 1-10 (2015)
Abstract Background It has been well accepted that glycans present in schistosomes are highly antigenic. However, it is not clear what kind of worm glycans can affect the infected host to mount IgG responses and whether mounted anti-glycan IgG respon
Externí odkaz:
https://doaj.org/article/da9de8880bad4cc489488def4374edbe