Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Fengjin, Zhou"'
Autor:
Guangyin Zhou, Ruiyang Li, Shihao Sheng, Jingtao Huang, Fengjin Zhou, Yan Wei, Han Liu, Jiacan Su
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Organoids are “mini-organs” that self-organize and differentiate from stem cells under in vitro 3D culture conditions, mimicking the spatial structure and function of tissues in vivo. Extracellular vesicles (EVs) are nanoscale phospholip
Externí odkaz:
https://doaj.org/article/8a9ecc7cdbb6411e88bd23dede3294d1
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Growing research has suggested an association between chronic inflammation and Intervertebral disc degeneration (IVDD), but whether there is a causal effect remains unknown. This study adopted two-sample Mendelian randomization (MR) approach
Externí odkaz:
https://doaj.org/article/9c54d0335cbd44c19fb84fe0576c2298
Autor:
Dongyang Zhou, Yan Wei, Shihao Sheng, Miaomiao Wang, Jiajing Lv, Bowen Zhao, Xiao Chen, Ke Xu, Long Bai, Yan Wu, Peiran Song, Liehu Cao, Fengjin Zhou, Hao Zhang, Zhongmin Shi, Jiacan Su
Publikováno v:
Bioactive Materials, Vol 37, Iss , Pp 378-392 (2024)
Posttraumatic osteoarthritis (PTOA) patients are often diagnosed by X-ray imaging at a middle-late stage when drug interventions are less effective. Early PTOA is characterized by overexpressed matrix metalloprotease 13 (MMP13). Herein, we constructe
Externí odkaz:
https://doaj.org/article/bf1d77c4081842d18c1ba3e0e28dcbeb
Autor:
Jian Wang, Dongyang Zhou, Guangchao Wang, Miaomiao Wang, Fuxiao Wang, Yafei Han, Xiao Chen, Yan Hu, Fengjin Zhou, Zhongmin Shi, Xiaoxiang Ren, Jiacan Su
Publikováno v:
Virtual and Physical Prototyping, Vol 19, Iss 1 (2024)
ABSTRACTIn bone tissue engineering, the search for improved repair methods is crucial, given the drawbacks of traditional strategies like donor site issues and immune rejection. Addressing these challenges, this paper introduces an innovative GelMA/B
Externí odkaz:
https://doaj.org/article/b67fc19678464b959d5f2d74e08a3453
Publikováno v:
Materials Today Bio, Vol 28, Iss , Pp 101167- (2024)
In confronting the global prevalence of bone-related disorders, bone tissue engineering (BTE) has developed into a critical discipline, seeking innovative materials to revolutionize treatment paradigms. Quantum dots (QDs), nanoscale semiconductor par
Externí odkaz:
https://doaj.org/article/285675732e944153a1690134bb82cb9e
Smart osteoclasts targeted nanomedicine based on amorphous CaCO3 for effective osteoporosis reversal
Autor:
Biao Yu, Qianmin Gao, Shihao Sheng, Fengjin Zhou, Zhen Geng, Yan Wei, Hao Zhang, Yan Hu, Sicheng Wang, Jianping Huang, Mengmeng Li, Jiacan Su
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Osteoporosis is characterized by an imbalance in bone homeostasis, resulting in the excessive dissolution of bone minerals due to the acidified microenvironment mediated by overactive osteoclasts. Oroxylin A (ORO), a natural flavo
Externí odkaz:
https://doaj.org/article/cd7c9f8672e249b3912fc45433b57249
Autor:
Han Liu, Peiran Song, Hao Zhang, Fengjin Zhou, Ning Ji, Mingkai Wang, Guangyin Zhou, Ruina Han, Xinru Liu, Weizong Weng, Haoqi Tan, Sicheng Wang, Lei Zheng, Yingying Jing, Jiacan Su
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 4, Pp n/a-n/a (2024)
Abstract Osteoporosis (OP) is a systematic bone disease characterized by low bone mass and fragile bone microarchitecture. Conventional treatment for OP has limited efficacy and long‐term toxicity. Synthetic biology makes bacterial extracellular ve
Externí odkaz:
https://doaj.org/article/0b9e503941bd4feb81eac0174242cfbc
Autor:
Yili Wang, Qiushui Lin, Hao Zhang, Sicheng Wang, Jin Cui, Yan Hu, Jinlong Liu, Mengmeng Li, Kun Zhang, Fengjin Zhou, Yingying Jing, Zhen Geng, Jiacan Su
Publikováno v:
Bioactive Materials, Vol 28, Iss , Pp 273-283 (2023)
Diabetes mellitus is a chronically inflamed disease that predisposes to delayed fracture healing. Macrophages play a key role in the process of fracture healing by undergoing polarization into either M1 or M2 subtypes, which respectively exhibit pro-
Externí odkaz:
https://doaj.org/article/03872149bc2f438c9b3bf4f066c13de0
Publikováno v:
Bioactive Materials, Vol 25, Iss , Pp 29-41 (2023)
The necessity of disease models for bone/cartilage related disorders is well-recognized, but the barrier between ex-vivo cell culture, animal models and the real human body has been pending for decades. The organoid-on-a-chip technique showed opportu
Externí odkaz:
https://doaj.org/article/7c3d33e2bca9443b9f3d1079aa09a857
Publikováno v:
Research, Vol 6 (2023)
Rapid and effective repair of injured or diseased bone defects remains a major challenge due to shortages of implants. Smart hydrogels that respond to internal and external stimuli to achieve therapeutic actions in a spatially and temporally controll
Externí odkaz:
https://doaj.org/article/9af8b4a85ace4648a6b8b145e6b74cd0