Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Fengji Xu"'
Publikováno v:
Pancreas. 44(2)
Autor:
Yinhua Yu, Jiaju Bao, Robert C. Bast, Fengji Xu, Rashmi Pershad, Jean Pierre J. Issa, Hongqi Peng, Yong Pang, Robert Z. Luo, Warren S.-L. Liao
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1519:216-222
We have recently identified a maternally imprinted tumor suppressor gene, ARHI (aplysia ras homolog I), the expression of which is lost in ovarian and breast cancers. We have now characterized the genomic structure of the gene including its promoter
Autor:
Mark A. Pershouse, Yinhua Yu, Ann M. Killary, Fengji Xu, Bruce D. Cuevas, Gordon B. Mills, Yofre Cabeza-Arvelaiz, Robert C. Bast, Jon R. Wiener, M. Mercedes Lovell, Russell P. Kruzelock
Publikováno v:
Oncogene. 19:6277-6285
The identity of many tumor suppressor genes important in epithelial ovarian cancer tumorigenesis remains unknown. In an effort to localize a novel tumor suppressor on chromosome 22, a psv2neo tagged human chromosome 22 was transferred into the malign
Autor:
Robert C. Bast, Estrid Høgdall, Bjørn Hagen, Claus Høgdall, Fengji Xu, Ian Jacobs, K. Nustad, Solveig Tingulstad
Publikováno v:
International Journal of Cancer. 89:519-523
Our objective was to compare the predictive value of the well-established tumour marker CA125 with the newer tumour markers tetranectin (TN), OVX1 and CASA in distinguishing benign and malignant pelvic masses in women. Participants included 185 women
Autor:
Fengji Xu, Hongqi Peng, Joe W. Gray, Marsha L. Frazier, Kelly K. Hunt, Andrew Berchuck, David W. Hogg, Robert C. Bast, Yinhua Yu, Rashmi Pershad
Publikováno v:
International Journal of Cancer. 86:690-694
In our previous work, we had characterized ARHI as an imprinted putative tumor-suppressor gene in ovarian and breast cancers. ARHI is expressed in primary breast and ovarian cell lines but largely absent from the corresponding malignant tumors. Moreo
Autor:
Yinhua Yu, Catherine F. Foulon, Fengji Xu, Robert C. Bast, Michael R. Zalutsky, Xiao-Guang Zhao, Susan Slade, Donna J. Affleck
Publikováno v:
Nuclear Medicine and Biology. 26:781-790
Monoclonal antibody (MAb) internalization can have a major effect on tumor retention of radiolabel. Two anti-HER-2/neu MAbs (TA1 and 520C9) were radioiodinated using the iodogen, N-succinimidyl 5-iodo-3-pyridinecarboxylate (SIPC), and tyramine-cellob
Autor:
Robert C. Bast, Fengji Xu, Cinda M. Boyer, K. DeSombre, Kathy O'Briant, Jon R. Wiener, Blanche Simpson Bast, Lajos Pusztai, Marilee Greenwald, G. Scott Dean
Publikováno v:
International Journal of Cancer. 82:525-531
Different epitopes on the extracellular domain of the HER-2 receptor can serve as distinct targets for immunotoxins. To determine the optimal epitope target for immunotoxin therapy, 7 anti-HER-2 ricin A chain murine monoclonal immunotoxins, each reac
Autor:
Hongqi Peng, Yang Li, Gordon B. Mills, Joe W. Gray, Xianjun Fang, Wen Lin Kuo, Michael J. Siciliano, Bruce D. Cuevas, Yinhua Yu, Robert C. Bast, Shulei Zhao, Fengji Xu
Publikováno v:
Proceedings of the National Academy of Sciences. 96:214-219
Using differential display PCR, we have identified a gene [ NOEY2 , ARHI (designation by the Human Gene Nomenclature Committee)] with high homology to ras and rap that is expressed consistently in normal ovarian and breast epithelial cells but not in
Autor:
Regina S. Whitaker, Robert M. Bell, Matthew P. Boente, Daniel L. Clarke-Pearson, A. Kalen, Robert C. Bast, Andrew Berchuck, Fengji Xu
Publikováno v:
Gynecologic Oncology. 70:49-55
Seven of 10 murine monoclonal antibodies reactive with the extracellular domain of p185c-erbB-2 inhibited the anchorage independent growth of the SKBr3 breast cancer cell line that overexpressed p185c-erbB-2. Significant inhibition (56-72%) of diacyl