Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Fengfeng L. Xu"'
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10819 (2010)
An increase in chromosome number, or polyploidization, is associated with a variety of biological changes including breeding of cereal crops and flowers, terminal differentiation of specialized cells such as megakaryocytes, cellular stress and oncoge
Externí odkaz:
https://doaj.org/article/8b2ae93f8d5d43be878d49f1a158d0d4
Publikováno v:
Journal of Biological Chemistry. 285:13183-13192
c-Myc (Myc) oncoprotein induction of genomic instability (GI) contributes to its initial transforming function and subsequent tumor cell evolution. We describe here a pathway by which Myc, via its target protein glycoprotein Ibalpha (GpIb alpha), med
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 5, p e10819 (2010)
PLoS ONE, Vol 5, Iss 5, p e10819 (2010)
An increase in chromosome number, or polyploidization, is associated with a variety of biological changes including breeding of cereal crops and flowers, terminal differentiation of specialized cells such as megakaryocytes, cellular stress and oncoge
Autor:
John S. Lazo, Youssef Rbaibi, Kirill Kiselyov, Fengfeng L. Xu, Peter Wipf, William S. Saunders
Publikováno v:
BMC Chemical Biology, Vol 10, Iss 1, p 1 (2010)
BMC Chemical Biology
BMC Chemical Biology
Background Disorazoles are polyene macrodiolides isolated from a myxobacterium fermentation broth. Disorazole C1 was newly synthesized and found to depolymerize microtubules and cause mitotic arrest. Here we examined the cellular responses to disoraz
Autor:
Bethany Petrik, John S. Lazo, Billy W. Day, Raghavan Balachandran, Carolyn A. Kitchens, Brianne S. Raccor, Jane R. Stout, Peter Wipf, Fengfeng L. Xu, Marni Brisson Tierno, Thomas H. Graham, Celeste E. Reese, William S. Saunders, Claire E. Walczak, Alexander P. Ducruet
Disorazoles comprise a family of 29 macrocyclic polyketides isolated from the fermentation broth of the myxobacterium Sorangium cellulosum. The major fermentation product, disorazole A(1), was found previously to irreversibly bind to tubulin and to h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485e802de4275d3e915fdfd0842dfd6d
https://europepmc.org/articles/PMC2649750/
https://europepmc.org/articles/PMC2649750/
Autor:
William S. Saunders, Fengfeng L. Xu
Publikováno v:
Cancer cell. 14(3)
Centrosomes are frequently amplified in cancer cells, but centrosome clustering pathways act to minimize their detrimental impact on mitosis. Recent data published online in Genes & Developments by Kwon et al. (2008) suggest that these pathways invol