Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Fengdi Zhao"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Alzheimer’s disease (AD) is an age-related neurodegenerative disorder with regulatory RNAs playing significant roles in its etiology. Circular RNAs (CircRNA) are enriched in human brains and contribute to AD progression. Many circRNA isofo
Externí odkaz:
https://doaj.org/article/b294eb761c754e6691741b06a82608f5
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5761-5774 (2022)
Traditional approaches for diagnosing Alzheimer’s disease (AD) such as brain imaging and cerebrospinal fluid are invasive and expensive. It is desirable to develop a useful diagnostic tool by exploiting biomarkers obtained from peripheral tissues d
Externí odkaz:
https://doaj.org/article/367d10f23b4f435387d628375b99289c
Publikováno v:
Bioinformatics. 39
Motivation Small insertion and deletion (sindel) of human genome has an important implication for human disease. One important mechanism for non-coding sindel (nc-sindel) to have an impact on human diseases and phenotypes is through the regulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a25b498acb842d56de5f50a5a6dd0409
https://doi.org/10.1093/bioinformatics/btad060
https://doi.org/10.1093/bioinformatics/btad060
Publikováno v:
Bioinformatics
Motivation Though genome-wide association studies have identified tens of thousands of variants associated with complex traits and most of them fall within the non-coding regions, they may not be the causal ones. The development of high-throughput fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6e4a11d478e58ade0cc1a6319816b8
https://pubmed.ncbi.nlm.nih.gov/35389435
https://pubmed.ncbi.nlm.nih.gov/35389435
Autor:
Zhenbo Zhang, Yingtao Liu, Yinhua Yu, Fengdi Zhao, Youji Feng, Chao Gu, Lianhua Yin, Xiaojun Chen
Publikováno v:
Cancer Science. 102:557-564
Progestin resistance is the main obstacle to successful conservative therapy in young endometrial cancer patients. To investigate the molecular events that lead to progestin resistance and to find a possible way to reverse progestin resistance in end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590fc3fb319e24fde45512445812f8b6
https://doi.org/10.1111/j.1349-7006.2010.01829.x
https://doi.org/10.1111/j.1349-7006.2010.01829.x
Publikováno v:
Journal of Zhejiang University SCIENCE B. 11:350-356
Objective: To determine the effect of steroidogenic acute regulatory protein (StAR) overexpression on the levels of adenosine triphosphate (ATP)-binding cassette transporter A1 (ABCA1) and ATP-binding cassette transporter G1 (ABCG1) in an endothelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c360e5ef3d9688c9769faac2cee66760
https://doi.org/10.1631/jzus.b0900369
https://doi.org/10.1631/jzus.b0900369
Publikováno v:
Lipids. 45:29-36
Steroidogenic acute regulatory protein (StAR) plays an important role in the maintenance of intracellular lipid homeostasis. Macrophages are the key cellular player in the pathophysiology of atherosclerosis. Imbalance of macrophage lipid homeostasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cdc17970b7ed7fc30538d75757ab37c
https://doi.org/10.1007/s11745-009-3375-6
https://doi.org/10.1007/s11745-009-3375-6
Autor:
Lianhua Yin, Qianming Bai, Yanxia Ning, Sifeng Chen, Fengdi Zhao, Xiaobo Li, Shunlin Ren, William M. Pandak, Hong Lu
Publikováno v:
Atherosclerosis. 204:114-120
Hyperlipidemia is one of the most important risk factors for atherosclerosis. This can be amplified by a localized inflammatory response mediated by macrophages. Macrophages are capable of taking up excess cholesterol, and it is well known that deliv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196702e468609cc7229b951296f22f42
https://doi.org/10.1016/j.atherosclerosis.2008.09.006
https://doi.org/10.1016/j.atherosclerosis.2008.09.006
Publikováno v:
Journal of Zhejiang University SCIENCE B. 9:656-661
Objective: To explore the effects of down-regulated tryptase expression in mast cells on the synthesis and release of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) of vascular endothelial cells. Methods: Tryptase-siRNA (small-interfer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9ae2376d8828a8ab776ae5ee28c5ac
https://doi.org/10.1631/jzus.b0810188
https://doi.org/10.1631/jzus.b0810188
Publikováno v:
Microvascular Research. 72:48-53
Cerebral ischemia and post-ischemic reperfusion commonly result in significant brain damage. Brain microvessel endothelial cells, the key target cells and regulating sites, can secrete adenosine which plays an important neuroprotective role in the is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d9a3a124da2be9e6e985413b133ee4
https://doi.org/10.1016/j.mvr.2006.04.005
https://doi.org/10.1016/j.mvr.2006.04.005