Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Fengcui Qian"'
Autor:
Xinyuan Zhou, Liwei Zhou, Fengcui Qian, Jiaxin Chen, Yuexin Zhang, Zhengmin Yu, Jian Zhang, Yongsan Yang, Yanyu Li, Chao Song, Yuezhu Wang, Desi Shang, Longlong Dong, Jiang Zhu, Chunquan Li, Qiuyu Wang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1877-1885 (2024)
Transcription factors (TFs) are major contributors to gene transcription, especially in controlling cell-specific gene expression and disease occurrence and development. Uncovering the relationship between TFs and their target genes is critical to un
Externí odkaz:
https://doaj.org/article/bba1ce15c5c34469894748eb52e542f9
Autor:
Chao Song, Yuexin Zhang, Hong Huang, Yuezhu Wang, Xilong Zhao, Guorui Zhang, Mingxue Yin, Chenchen Feng, Qiuyu Wang, Fengcui Qian, Desi Shang, Jian Zhang, Jiaqi Liu, Chunquan Li, Huifang Tang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 655-667 (2023)
Cis-regulatory elements are important molecular switches in controlling gene expression and are regarded as determinant hubs in the transcriptional regulatory network. Collection and processing of large-scale cis-regulatory data are urgent to deciphe
Externí odkaz:
https://doaj.org/article/4187cc68d7e348d58fecf84ca504fce9
Autor:
Chenchen Feng, Chao Song, Yong Jiang, Jun Zhao, Jian Zhang, Yuezhu Wang, Mingxue Yin, Jiang Zhu, Bo Ai, Qiuyu Wang, Fengcui Qian, Yuexin Zhang, Desi Shang, Jiaqi Liu, Chunquan Li
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 385-401 (2023)
A core transcription regulatory circuitry (CRC) is an interconnected self-regulatory circuitry that is formed by a group of core transcription factors (TFs). These core TFs collectively regulate gene expression by binding not only to their own super
Externí odkaz:
https://doaj.org/article/fca1fb10f0c245a0b76b17658326da36
Autor:
Yu Gao, Chenchen Feng, Yuexin Zhang, Chao Song, Jiaxin Chen, Yanyu Li, Ling Wei, Fengcui Qian, Bo Ai, Yuejuan Liu, Jiang Zhu, Xiaojie Su, Chunquan Li, Qiuyu Wang
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
MicroRNAs (miRNAs) are small non-coding RNAs, which play important roles in regulating various biological functions. Many available miRNA databases have provided a large number of valuable resources for miRNA investigation. However, not all existing
Externí odkaz:
https://doaj.org/article/2228cca830e348848b55a348171637f1
Autor:
Ling Wei, Jiaxin Chen, Chao Song, Yuexin Zhang, Yimeng Zhang, Mingcong Xu, Chenchen Feng, Yu Gao, Fengcui Qian, Qiuyu Wang, Desi Shang, Xinyuan Zhou, Jiang Zhu, Xiaopeng Wang, Yijie Jia, Jiaqi Liu, Yanbing Zhu, Chunquan Li
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
A core transcriptional regulatory circuit (CRC) is a group of interconnected auto-regulating transcription factors (TFs) that form loops and can be identified by super-enhancers (SEs). Studies have indicated that CRCs play an important role in defini
Externí odkaz:
https://doaj.org/article/345a53849f854199860287708b5a45b5
Autor:
Yuezhu Wang, Chao Song, Jun Zhao, Yuexin Zhang, Xilong Zhao, Chenchen Feng, Guorui Zhang, Jiang Zhu, Fan Wang, Fengcui Qian, Liwei Zhou, Jian Zhang, Xuefeng Bai, Bo Ai, Xinyu Liu, Qiuyu Wang, Chunquan Li
Publikováno v:
Nucleic Acids Research. 51:D280-D290
Super-enhancers (SEs) are cell-specific DNA cis-regulatory elements that can supervise the transcriptional regulation processes of downstream genes. SEdb 2.0 (http://www.licpathway.net/sedb) aims to provide a comprehensive SE resource and annotate th
Autor:
Jianmei Zhao, Fengcui Qian, Xuecang Li, Zhengmin Yu, Jiang Zhu, Rui Yu, Yue Zhao, Ke Ding, Yanyu Li, Yongsan Yang, Qi Pan, Jiaxin Chen, Chao Song, Qiuyu Wang, Jian Zhang, Guohua Wang, Chunquan Li
Publikováno v:
Bioinformatics (Oxford, England). 39(1)
Motivation DNA methylation within gene body and promoters in cancer cells is well documented. An increasing number of studies showed that cytosine–phosphate–guanine (CpG) sites falling within other regulatory elements could also regulate target g
Autor:
Yongsan Yang, Fengcui Qian, Xuecang Li, Yanyu Li, Liwei Zhou, Qiuyu Wang, Xinyuan Zhou, Jian Zhang, Chao Song, Zhengmin Yu, Ting Cui, Chenchen Feng, Jiang Zhu, Desi Shang, Jiaqi Liu, Mengfei Sun, Yuexin Zhang, Huifang Tang, Chunquan Li
Publikováno v:
Briefings in bioinformatics. 23(5)
The rapid development of genomic high-throughput sequencing has identified a large number of DNA regulatory elements with abundant epigenetics markers, which promotes the rapid accumulation of functional genomic region data. The comprehensively under
Autor:
Jianmei Zhao, Chenchen Feng, Yongsan Yang, Yong Jiang, Yanyu Li, Yuexin Zhang, Fengcui Qian, Minghong Feng, Yu Gao, Qiuyu Wang, Ziyu Ning, Junwei Han, Jiaxin Chen, Ling Wei, Chunquan Li, Xinyuan Zhou, Qi Pan, Chao Song, Jian Zhang
Publikováno v:
Nucleic Acids Research
Long non-coding RNAs (lncRNAs) have been proven to play important roles in transcriptional processes and various biological functions. Establishing a comprehensive collection of human lncRNA sets is urgent work at present. Using reference lncRNA sets
Autor:
De-Chen Lin, Fan Wang, En-Min Li, Liu Peng, Yang Chen, Yanyu Li, Yuexin Zhang, Qiuyu Wang, Li-Yan Xu, Jiaxin Chen, Meng Li, Chunquan Li, Fengcui Qian, Lian-Di Liao
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 14, Iss 9, Pp 2203-2230 (2020)
Molecular Oncology, Vol 14, Iss 9, Pp 2203-2230 (2020)
Long noncoding RNAs (lncRNAs) have important regulatory roles in cancer biology. Although some lncRNAs have well‐characterized functions, the vast majority of this class of molecules remains functionally uncharacterized. To systematically pinpoint