Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Fengchun Hua"'
Autor:
Na Qi, Hao Wang, Haiyan Wang, Shuhua Ren, Zhiwen You, Xing Chen, Yihui Guan, Fang Xie, Fengchun Hua, Jun Zhao
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectiveFibroblast activation protein (FAP)-targeting radiopharmaceutical based on the FAP-specific inhibitor (FAPI) is considered as a potential alternative agent to FDG for tumor-specific imaging. However, FAP is also expressed in normal adult tis
Externí odkaz:
https://doaj.org/article/dcd93c2d1efe4677b797d5cb5421d8dd
Autor:
Junpeng Li, Da Shao, Donglang Jiang, Qi Huang, Yihui Guan, Bin Lai, Jun Zhao, Fengchun Hua, Fang Xie
Publikováno v:
EJNMMI Research, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Background Accumulating evidence indicates that neuroinflammation (NI) significantly contributes to drug addiction, but the conversion of NI after drug withdrawal is not clear. Here, we conducted 18F-flutriciclamide (GE180) positron emission
Externí odkaz:
https://doaj.org/article/b20a655edc9a40968eca735d67b85a90
Autor:
Panlong Li, Qi Huang, Shiyu Ban, Yuan Qiao, Jing Wu, Yu Zhai, Xiaoxia Du, Fengchun Hua, Jingjing Su
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Background and Purpose: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy caused by mutations in the NOTCH3 gene is a hereditary cerebral small vessel disease, manifesting with stroke, cognitive impairment, an
Externí odkaz:
https://doaj.org/article/2b2c751b8b6942178a99aeab00f7b4ab
Autor:
Jingjing Su, Shiyu Ban, Mengxing Wang, Fengchun Hua, Liang Wang, Xin Cheng, Yuping Tang, Houguang Zhou, Yu Zhai, Xiaoxia Du, Jianren Liu
Publikováno v:
The Journal of Headache and Pain, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) manifests principally as a suite of cognitive impairments, particularly in the executive domain. Executive functioning requires t
Externí odkaz:
https://doaj.org/article/967a6baf2c3744069f486cf0b44da5c7
Autor:
Jingjing Su, Mengxing Wang, Shiyu Ban, Liang Wang, Xin Cheng, Fengchun Hua, Yuping Tang, Houguang Zhou, Yu Zhai, Xiaoxia Du, Jianren Liu
Publikováno v:
The Journal of Headache and Pain, Vol 20, Iss 1, Pp 1-11 (2019)
Abstract Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) mainly manifests with cognitive impairment. Cognitive deficits in patients with CADASIL are correlated with structural brain chan
Externí odkaz:
https://doaj.org/article/3fb62e8c20174909ba30fb7b8a4ffd61
Autor:
Wei Hu, Donghui Pan, Yalin Wang, Weiqi Bao, Chuantao Zuo, Yihui Guan, Fengchun Hua, Min Yang, Jun Zhao
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Background: In the pathogenesis of Alzheimer's disease (AD), microglia play an increasingly important role. Molecular imaging of neuroinflammatory targeting microglia activation and the high expression of 18-kDa translocator protein (TSPO) has become
Externí odkaz:
https://doaj.org/article/d7a707579c124a95aeda91338efe6910
Autor:
Donglang Jiang, Xiuhong Lu, Zijing Li, Nicklas Rydberg, Chuantao Zuo, Fangyu Peng, Fengchun Hua, Yihui Guan, Fang Xie
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2019)
Background: Brain development and maturation in adolescence is a complex process with active changes of metabolic and neurotransmission pathways. Positron emission tomography (PET) is a useful imaging modality for tracking metabolic and functional ch
Externí odkaz:
https://doaj.org/article/7a56551c244849ba87546904d67254b9
Autor:
Yanyan Kong, Yihui Guan, Fengchun Hua, Zhengwei Zhang, Xiuhong Lu, Tengfang Zhu, Bizeng Zhao, Jianhua Zhu, Cong Li, Jian Chen
Publikováno v:
Molecules, Vol 21, Iss 8, p 1019 (2016)
The quantification of neurofibrillary tangles (NFTs) using specific PET tracers can facilitate the diagnosis of Alzheimer’s disease (AD) and allow monitoring of disease progression and treatment efficacy. [18F]-THK523 has shown high affinity and se
Externí odkaz:
https://doaj.org/article/cea847db7aa14216944244f6e7e14e0b
Autor:
Shuhua Ren, Junpeng Li, Lin Huang, Qi Huang, Kewei Chen, Jingchao Hu, Frank Jessen, Xiaochen Hu, Donglang Jiang, Lin Zhu, Xiaomin Wang, Yihui Guan, Fengchun Hua, Qihao Guo, Fang Xie
Publikováno v:
Neuroscience 513, 137-144 (2023). doi:10.1016/j.neuroscience.2023.01.004
Subjective cognitive decline (SCD) and objective subtle cognitive difficulties (Obj-SCD) are considered the initial stages of aberrant cognition prior to mild cognitive impairment (MCI) due to Alzheimer's disease (AD). We aimed to determine the diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565ec5f91e379009ea92e5a77f6518dd
Autor:
Yihui Guan, Fengchun Hua, Xiuming Li, Fang Xie, Xing Chen, Shuhua Ren, Zhiwen You, Hao Wang, Qi Huang, Donglang Jiang, Jun Zhao, Xiaoyun Zhang
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 49:732-742
The low sensitivity of [18F]-fluorodeoxyglucose ([18F]-FDG) for the diagnosis of gastric cancer limits its application. In this study, we aimed to investigate the potential advantage of [68 Ga]Ga-FAPI-04 over [18F]-FDG in the evaluation of gastric ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e66177f262971b7c628fce90fcce659
https://doi.org/10.1007/s00259-021-05441-w
https://doi.org/10.1007/s00259-021-05441-w