Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Fengchen Shen"'
Publikováno v:
Kidney Diseases, Vol 8, Iss 6, Pp 466-477 (2022)
Background: Acute kidney injury( AKI) is a serious clinical problem associated with high morbidity and mortality worldwide. The pathophysiology and pathogenesis of AKI is complex and multifactorial. In recent years, epigenetics has emerged as an impo
Externí odkaz:
https://doaj.org/article/171f800c70ee4a8d838d4e605dbb90c6
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Expression and function of histone deacetylases (HDACs) vary with cell types and pathological conditions. Our recent studies showed that pharmacological targeting class IIa HDACs attenuated renal fibrosis, but the effect of class IIa HDAC inhibition
Externí odkaz:
https://doaj.org/article/2d1884dd79c94f2493c153cd4b69dba0
Autor:
Fengchen Shen, Xiying Hou, Tingting Li, Jianjun Yu, Huizhen Chen, Na Liu, Andong Qiu, Shougang Zhuang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Histone deacetylase 4 (HDAC4) has been shown to be involved in cell proliferation, differentiation, and migration and is associated with a variety of cancers. However, the role of HDAC4 in renal fibrogenesis and its mechanisms are unclear. We assesse
Externí odkaz:
https://doaj.org/article/e6b513c1255349a7b155d9cbc8206542
Autor:
Jianni Huang, Hao Cao, Binbin Cui, Xiaoyan Ma, Ling Gao, Chao Yu, Fengchen Shen, Xinyu Yang, Na Liu, Andong Qiu, Guangyan Cai, Shougang Zhuang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Exosomes are membrane-enclosed vesicles secreted by cells, containing a variety of biologically active ingredients including proteins, nucleic acids and lipids. In this study, we investigated the therapeutic effects of the exosomes and underlying mec
Externí odkaz:
https://doaj.org/article/4fa59f4578c640969966f85c3037c3f3
Autor:
Fengchen Shen, Shougang Zhuang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Histones are the most abundant proteins bound to DNA in eukaryotic cells and frequently subjected to post-modifications such as acetylation, methylation, phosphorylation and ubiquitination. Many studies have shown that histone modifications, especial
Externí odkaz:
https://doaj.org/article/d6057582fad847759123626466b7680b
Autor:
Fengchen Shen, Shougang Zhuang
Publikováno v:
Frontiers in pharmacology. 13
Histones are the most abundant proteins bound to DNA in eukaryotic cells and frequently subjected to post-modifications such as acetylation, methylation, phosphorylation and ubiquitination. Many studies have shown that histone modifications, especial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38aed597288dcf7e00a35e52bc473de
https://pubmed.ncbi.nlm.nih.gov/35559244
https://pubmed.ncbi.nlm.nih.gov/35559244