Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Fengbiao Mao"'
Autor:
Zhipeng Zhu, Huang Cao, Hongyu Yan, Hanzhi Liu, Zaifa Hong, Anran Sun, Tong Liu, Fengbiao Mao
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 929-941 (2024)
Cancer immunotherapy has shown to be a promising method in treating hepatocellular carcinoma (HCC), but suboptimal responses in patients are attributed to cellular and molecular heterogeneity. Iron metabolism-related genes (IRGs) are important in mai
Externí odkaz:
https://doaj.org/article/8dfb45de7eba49c2b458a98ee300c728
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-52 (2024)
Abstract Multicellular organisms are composed of diverse cell types that must coordinate their behaviors through communication. Cell–cell communication (CCC) is essential for growth, development, differentiation, tissue and organ formation, mainten
Externí odkaz:
https://doaj.org/article/1652bc7fe38d4d93b50f4be7125c933c
Autor:
Le Tran Phuc Khoa, Wentao Yang, Mengrou Shan, Li Zhang, Fengbiao Mao, Bo Zhou, Qiang Li, Rebecca Malcore, Clair Harris, Lili Zhao, Rajesh C. Rao, Shigeki Iwase, Sundeep Kalantry, Stephanie L. Bielas, Costas A. Lyssiotis, Yali Dou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Quiescence in stem cells is traditionally considered as a state of inactive dormancy or with poised potential. Naive mouse embryonic stem cells (ESCs) can enter quiescence spontaneously or upon inhibition of MYC or fatty acid oxidation, mimi
Externí odkaz:
https://doaj.org/article/6b1a1bc377ca40f2bfe4471b19c2237e
Autor:
Chaoxin Wang, Jinge Liu, Shuyuan Min, Yu Liu, Bingchuan Liu, Yuanyu Hu, Zhengguang Wang, Fengbiao Mao, Caimei Wang, Xiaolin Ma, Peng Wen, Yufeng Zheng, Yun Tian
Publikováno v:
Bioactive Materials, Vol 28, Iss , Pp 537-548 (2023)
The effects of pore size in additively manufactured biodegradable porous magnesium on the mechanical properties and biodegradation of the scaffolds as well as new bone formation have rarely been reported. In this work, we found that high temperature
Externí odkaz:
https://doaj.org/article/73e314bf106140c898c52b16c012abbf
Autor:
Le Tran Phuc Khoa, Wentao Yang, Mengrou Shan, Li Zhang, Fengbiao Mao, Bo Zhou, Qiang Li, Rebecca Malcore, Clair Harris, Lili Zhao, Rajesh C. Rao, Shigeki Iwase, Sundeep Kalantry, Stephanie L. Bielas, Costas A. Lyssiotis, Yali Dou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/99c1bf8c94c5449d90874ae8fbf5c9e4
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/89eada9c57804494ba33efa3c936f3a5
Autor:
Yifan Chen, Shanwu Ma, Chutong Lin, Zhipeng Zhu, Jie Bai, Zhongnan Yin, Yan Sun, Fengbiao Mao, Lixiang Xue, Shaohua Ma
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Lung cancer is a leading cause of cancer-related deaths worldwide, with a low 5-year survival rate due in part to a lack of clinically useful biomarkers. Recent studies have identified DNA methylation changes as potential cancer biomarkers. The prese
Externí odkaz:
https://doaj.org/article/140dd14f095748b7858b1128cc7501cb
Autor:
Shasha Li, Chenyang Lu, Yuan Zhang, Xiaolu Zhao, Kequan Lin, Xiufang Kong, David Fox, Lixiang Xue, Lichao Sun, Yi Liu, Fengbiao Mao
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104631- (2022)
Summary: Autoimmune diseases (ADs) are at a significantly higher risk of cancers with unclear mechanism. By searching GWAS catalog database and Medline, susceptible genes for five common ADs, including systemic lupus erythematosus (SLE), rheumatoid a
Externí odkaz:
https://doaj.org/article/2248d22ab6c9499b8556224e4abd7470
Autor:
David S. Rogawski, Jing Deng, Hao Li, Hongzhi Miao, Dmitry Borkin, Trupta Purohit, Jiho Song, Jennifer Chase, Shuangjiang Li, Juliano Ndoj, Szymon Klossowski, EunGi Kim, Fengbiao Mao, Bo Zhou, James Ropa, Marta Z. Krotoska, Zhuang Jin, Patricia Ernst, Xiaomin Feng, Gang Huang, Kenichi Nishioka, Samantha Kelly, Miao He, Bo Wen, Duxin Sun, Andrew Muntean, Yali Dou, Ivan Maillard, Tomasz Cierpicki, Jolanta Grembecka
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The histone methyltransferase ASH1L plays a role in various diseases, including cancer, and has been validated as a therapeutic target; however, no inhibitors of ASH1L have been reported. Here the authors present small molecule inhibitors of ASH1L an
Externí odkaz:
https://doaj.org/article/a51c519c90294569ac5da97219844f37
Autor:
Young-Tae Lee, Alex Ayoub, Sang-Ho Park, Liang Sha, Jing Xu, Fengbiao Mao, Wei Zheng, Yang Zhang, Uhn-Soo Cho, Yali Dou
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Regulation of the MLL family of histone H3K4 methyltransferases on the nucleosome core particle (NCP) remains largely unknown. Here the authors show that intrinsically disordered regions of ASH2L and DPY30 restrict the rotational dynamics of MLL1 on
Externí odkaz:
https://doaj.org/article/579dbc95fb704acb953fca9b4d33ed4c