Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Feng-dan Zhu"'
Autor:
Feng-Dan Zhu, Yu-Jiao Hu, Lu Yu, Xiao-Gang Zhou, Jian-Ming Wu, Yong Tang, Da-Lian Qin, Qing-Ze Fan, An-Guo Wu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Neuroinflammation, an inflammatory response within the central nervous system (CNS), is a main hallmark of common neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS), a
Externí odkaz:
https://doaj.org/article/40f65f54267044a3963fe6bd030630a2
Autor:
Minsong Guo, Lu Yu, Xiao-Gang Zhou, Qiu Wenqiao, Chong-Lin Yu, An-Guo Wu, Yong Tang, Betty Yuen Kwan Law, Feng-Dan Zhu, Dalian Qin, Gan Qiao, Jianming Wu
Publikováno v:
Acta Pharmaceutica Sinica B. 12:1723-1739
Discovery of drugs rapidly and effectively is an important aspect for Alzheimer's disease (AD). In this study, a novel high-throughput screening (HTS) method aims at screening the small-molecules with amyloid-β (Aβ) binding affinity from natural me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9aefc6ba63839129276708f9256f3fad
https://doi.org/10.1016/j.apsb.2021.08.030
https://doi.org/10.1016/j.apsb.2021.08.030
Autor:
Lu Yan, Min-Song Guo, Yue Zhang, Lu Yu, Jian-Ming Wu, Yong Tang, Wei Ai, Feng-Dan Zhu, Betty Yuen-Kwan Law, Qi Chen, Chong-Lin Yu, Vincent Kam-Wai Wong, Hua Li, Mao Li, Xiao-Gang Zhou, Da-Lian Qin, An-Guo Wu
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-40
Neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s disease (HD), are characterized by the progressive degeneration of neurons. Although the etiology and pathogenesis of neurodegenerative d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87fc4ad67726b11c3234c7fa8ebe2490
https://doi.org/10.1155/2022/5288698
https://doi.org/10.1155/2022/5288698
Polygala saponins inhibit NLRP3 inflammasome-mediated neuroinflammation via SHP-2-Mediated mitophagy
Autor:
Wen-Qiao Qiu, Wei Ai, Feng-Dan Zhu, Yue Zhang, Min-Song Guo, Betty Yuen-Kwan Law, Jian-Ming Wu, Vincent Kam-Wai Wong, Yong Tang, Lu Yu, Qi Chen, Chong-Lin Yu, Jian Liu, Da-Lian Qin, Xiao-Gang Zhou, An-Guo Wu
Publikováno v:
Free Radical Biology and Medicine. 179:76-94
Activation of the NLRP3 inflammasome and its mediated neuroinflammation are implicated in neurodegenerative diseases, while mitophagy negatively regulates NLRP3 inflammasome activation. SHP-2, a protein-tyrosine phosphatase, is critical for NLRP3 inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a71aebe2d00c961a2453ba70a4d5c6
https://doi.org/10.1016/j.freeradbiomed.2021.12.263
https://doi.org/10.1016/j.freeradbiomed.2021.12.263
Publikováno v:
Journal of Highway and Transportation Research and Development (English Edition). 10:34-39
The multilevel mixing method for aggregate gradation design was optimized based on the division of the functions of coarse and fine aggregates. The mixing procedures were simplified. The mi...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8a95288d5c3cff823aee6e695bce58c
https://doi.org/10.1061/jhtrcq.0000532
https://doi.org/10.1061/jhtrcq.0000532