Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Feng-Yuan Tsai"'
Publikováno v:
International Journal of Nanomedicine. 15:8411-8426
Background Gold nanoparticles with high biocompatibility and immunomodulatory properties have potential applications in the development of new diagnostic and therapeutic strategies for nanomedicine. Nanoparticles targeting macrophages can manipulate
Autor:
Tsui-Chun Tsou, Feng Yuan Tsai, Jhih Wei Hsu, Szu Ching Yeh, Hsin Wei Chen, Yung Hsi Kao, Chung Yi Nien
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 156
Both phthalate exposure and obesity are positively associated with metabolic disorders. The study aimed to investigate whether DEHP exposure caused metabolic disorders in an obesity-dependent manner. Both lean and diet-induced obese mice were subject
Publikováno v:
Journal of Applied Toxicology. 37:1537-1546
The study aimed to examine effects of environmental estrogens at body burden levels on energy metabolism in fat cells. Acclimation of T47D-KBluc cells in estrogen-deprived medium was established for high performance of estrogen-responsive luciferase
Autor:
Feng Yuan Tsai, Hsin Wei Chen, Yung Hsi Kao, Szu Ching Yeh, Tsui-Chun Tsou, Shen Liang Chen, Jhih Wei Hsu, Chung Yi Nien, Tzong Shyuan Lee
Publikováno v:
Food and Chemical Toxicology. 142:111487
Mono(2-ethylhexyl)phthalate (MEHP) promotes adipogenesis via PPARγ. PPARγ agonists, e.g., rosiglitazone (RSG), enhance adipocyte browning. However, scientific evidence regarding MEHP as a browning chemical is lacking. This study combined 3T3-L1 adi
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 59
Previous studies revealed that cellular accumulation of mono(2-ethylhexyl)phthalate (MEHP) disturbed energy metabolism in adipocytes, where glucose uptake was significantly increased. The present study aimed to determine the mechanisms underlying the
Publikováno v:
Environmental Technology & Innovation. 4:8-16
Dioxin-responsive element (DRE)-driven luciferase reporter assay is a rapid and cost-effective screening method for detection and semi-quantitation of dioxins and dioxin-like chemicals in samples from a variety of matrices. However, most of such stab
Autor:
Chung-Yu Chen, Feng-Yuan Tsai, Long-Sen Chang, Jeh-Jeng Wang, Hsien-Chang Lin, Wan-Ping Hu, Yin-Kai Chen, Chia-Chen Hsu, Ping-Jyun Sung
Publikováno v:
Cell Biology and Toxicology. 29:85-99
Melanoma is one of the most chemoresistant cancers in patient care. The remission rate of current therapy remains low. DC-81, an antitumor antibiotic produced by Streptomyces species, belongs to pyrrolo[2,1-c][1,4]benzodiazepine (PBD), which is a pot
Autor:
Chih Wei Liao, Huai chih Chiang, Yi Hua Lin, Tsui-Chun Tsou, Szu Ching Yeh, Feng Yuan Tsai, Wei Yu Lin, Chih-Hong Wang, Ya Ting Kuo, Wen Han Chuang
Publikováno v:
Cell biology and toxicology. 33(6)
Cellular accumulation of mono(2-ethylhexyl)phthalate (MEHP) has been recently demonstrated to disturb fat cell energy metabolism; however, the underlying mechanism remained unclear. The study aimed to determine how MEHP influenced fat cell transcript
Publikováno v:
Bulletin of Environmental Contamination and Toxicology. 87:113-116
Using one particulate zinc oxide (ZnO) and two soluble zinc compounds (Zn(NO(3))(2) and Zn(CH(3)COO)(2)), we aimed to clarify if zinc ions (Zn(2+)), like particulate ZnO, caused inflammatory responses in vascular endothelial cells. Treatments of huma
Zinc oxide particles induce inflammatory responses in vascular endothelial cells via NF-κB signaling
Autor:
Tsui-Chun Tsou, Feng-Yuan Tsai, How-Ran Chao, Tsun-Jen Cheng, Lin-Ai Tai, Ho-Jane Lin, Szu-Ching Yeh
Publikováno v:
Journal of Hazardous Materials. 183:182-188
This study investigated inflammatory effects of zinc oxide (ZnO) particles on vascular endothelial cells. The effects of 50 and 100-nm ZnO particles on human umbilical vein endothelial cells (HUVECs) were characterized by assaying cytotoxicity, cell