Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Feng-Yin Hsieh"'
Autor:
Burgess Laurence E, Leyla Arik, Chester Chenguang Yuan, Nianhe Han, Randall W. Hungate, Derin C. D'amico, David A. Mareska, Feng-Yin Hsieh, Eileen Johnson, Hong Sun, Qingyian Liu, Barton H. Manning, Bobby Riahi, Christopher H. Fotsch, Gloria Biddlecome, Mark H. Norman, Augustus Kamassah, Ming Huang, Richard Loeloff, Gondi N. Kumar, Andras Toro, Jian J. Chen, Jason Brooks Human, Hideo Suzuki, Robert D. Groneberg, Benny C. Askew, Aiwen Li, Gordon Ng, James Zhan, Kaustav Biswas, Dianna Lester-Zeiner, Hong Dong, David E. Clarke
Publikováno v:
Journal of Medicinal Chemistry. 50:2200-2212
The bradykinin B1 receptor is induced following tissue injury and/or inflammation. Antagonists of this receptor have been studied as promising candidates for treatment of chronic pain. We have identified aryl sulfonamides containing a chiral chroman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb42b5aad05a1dc5bda8d29f83bc6dc6
https://doi.org/10.1021/jm070055c
https://doi.org/10.1021/jm070055c
Autor:
Nuria A. Tamayo, Shimin Xu, Michael G. Kelly, Duncan M. Smith, Ning Chen, Michelle Carmouche, Mark H. Norman, Martin H. Goldberg, James Davis, Christopher H. Fotsch, Clarence Hale, Ning Xi, Markian Stec, James W. Baumgartner, Premilla Arasasingham, Nianhe Han, Feng-Yin Hsieh, Qingyian Liu, Yunxin Bo, Anthony W. Bannon
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:1623-1627
The biological activity for a set of melanocortin-4 receptor (MC4R) agonists containing a piperazine core with an ortho-substituted aryl sulfonamide is described. Compounds from this set had binding and functional activities at MC4R less than 30 nM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e26bb6cb3766754fe8c0250af2dfad
https://doi.org/10.1016/j.bmcl.2005.01.060
https://doi.org/10.1016/j.bmcl.2005.01.060
Autor:
Ian A. Blair, Feng-Yin Hsieh, Scott W. Womble, Robert F. Mayol, Brian J. Nobes, Charles A. Goldthwaite, Lewis J. Klunk
Publikováno v:
Analytical Chemistry. 68:2996-3001
Chemical reaction interface mass spectrometry (CRIMS) was coupled on-line with HPLC using a Vestec particle beam interface. A helium-assisted nebulizer provided added stability with no loss in accuracy or precision as compared to the thermospray nebu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4aa622bb0d8f73613d927714a83815f
https://doi.org/10.1021/ac960044j
https://doi.org/10.1021/ac960044j
Autor:
Hong Sun, Robert T. Fremeau, Kaustav Biswas, Sonya G. Lehto, Tanya Peterkin, Marian C. Bryan, Feng-Yin Hsieh, Cen Xu, Leyla Arik, Jennifer R. Allen
Publikováno v:
Journal of medicinal chemistry. 54(20)
The bradykinin B1 receptor is rapidly induced upon tissue injury and inflammation, stimulating the production of inflammatory mediators resulting in plasma extravasation, leukocyte trafficking, edema, and pain. We have previously reported on sulfonam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9576e5f24c309cf3f541b243e25c1c7d
https://pubmed.ncbi.nlm.nih.gov/21902230
https://pubmed.ncbi.nlm.nih.gov/21902230
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4d39aa8ad2690ea2e6cf85422aecfe5
https://doi.org/10.1002/chin.199649027
https://doi.org/10.1002/chin.199649027
A new class of bradykinin 1 receptor antagonists containing the piperidine acetic acid tetralin core
Autor:
David A. Mareska, Eileen Johnson, Christopher H. Fotsch, Dianna Lester-Zeiner, Qingyian Liu, Gloria Biddlecome, Gordon Ng, James Zhan, Kaustav Biswas, Nianhe Bruce Han, Yueh-Ju Judy Wang, Joe Zhu, Babak Riahi, Gondi N. Kumar, Kevin Yang, Robert D. Groneberg, Derin C. D'amico, Feng-Yin Hsieh, Jian Jeff Chen, Benny C. Askew, Augustus Kamassah
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(8)
The bradykinin 1 (B1) receptor is upregulated during times of inflammation and is important for maintaining inflamed and chronic pain states. Blocking this receptor has been shown to reverse and/or ameliorate pain and inflammation in animal models. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5310f114bdf0cdb04629d50164f8f659
https://pubmed.ncbi.nlm.nih.gov/16464576
https://pubmed.ncbi.nlm.nih.gov/16464576
Autor:
Takashi Yoneda, Yoshiyu Takeda, Ryoyu Takeda, Isamu Miyamori, Kazuhiro Iki, Ian A. Blair, Haruhiko Hatakeyama, Feng-Yin Hsieh
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 25(2)
Abstract Angiotensin I (Ang I), Ang II, angiotensinogen, and renin are formed locally in the vasculature. We undertook this study to determine whether the rat mesenteric artery produces aldosterone and to investigate the effects of adrenalectomy, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f5c68246e93b53584d950aac8264e95
https://pubmed.ncbi.nlm.nih.gov/7843766
https://pubmed.ncbi.nlm.nih.gov/7843766
Autor:
Kaustav Biswas, Tanya A. N. Peterkin, Marian C. Bryan, Leyla Arik, Sonya G. Lehto, Hong Sun, Feng-Yin Hsieh, Cen Xu, Robert T. Fremeau, Jennifer R. Allen
Publikováno v:
Journal of Medicinal Chemistry; Oct2011, Vol. 54 Issue 20, p7232-7246, 15p