Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Feng-Jin Guo"'
Autor:
Jun-ming Huang, Ran-yue Ren, Yuan Bao, Jia-chao Guo, Wei Xiang, Xing-zhi Jing, Jia Shi, Guo-xiang Zhang, Long Li, Yong Tian, Hao Kang, Feng-jin Guo
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/368cd20561644b43844e1f9bd8cc0626
Autor:
Jun-ming Huang, Ran-yue Ren, Yuan Bao, Jia-chao Guo, Wei Xiang, Xing-zhi Jing, Jia Shi, Guo-xiang Zhang, Long Li, Yong Tian, Hao Kang, Feng-jin Guo
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Recent studies indicate that uPAR acts a crucial part in cell migration and the modulation of bone homeostasis. As a natural serine protease inhibitor, ulinastatin owns the capacity to reduce proinflammatory factors, downregulate the activation of NF
Externí odkaz:
https://doaj.org/article/4b8c488363424227bfa1d88043cfc7a4
Publikováno v:
The FEBS Journal. 287:2348-2366
Endoplasmic reticulum (ER) stress and autophagy dysfunction contribute to the establishment and progression of diverse pathologies. Proteolytic activation of the transcription factor nSREBP1 is induced under ER stress; however, little is known about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d627d3ad9390bbf5a631b3e2d01b88c2
https://doi.org/10.1111/febs.15144
https://doi.org/10.1111/febs.15144
Autor:
Yangli Xie, Feng-Jin Guo, Lin Deng, Li Liang, Dongsheng Yu, Mengying Zhang, Yu Du, Yuyou Yang, Xiaoli Li, Mengtian Fan, Cheng Chen, Qizhong Qin, Fangzhou Song, Naibo Feng, Nana Geng, Menglin Xian, Qiaoyan Tan, Fengtao Luo, Rong Jiang, Huabing Qi, Xingyue Li
Publikováno v:
ACS nano. 15(10)
The clinical application of small interfering RNA (siRNA) drugs provides promising opportunities to develop treatment strategies for autoimmune inflammatory diseases. In this study, siRNAs targeting the endoplasmic reticulum to nucleus signaling 1 (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302c7c9476c93f92473501de47b9237a
https://pubmed.ncbi.nlm.nih.gov/34586802
https://pubmed.ncbi.nlm.nih.gov/34586802
Autor:
Liang Chen, Zuqiang Wang, Hangang Chen, Junjie Ouyang, Nan Su, Chuan-ju Liu, Zhenhong Ni, Siru Zhou, Yan Xiong, Peng Liu, Lin Chen, Fengtao Luo, Liangjun Yin, Jiangyi Wu, Huabing Qi, Jing Yang, Qiaoyan Tan, Bin Zhang, Shuai Chen, Wanling Jiang, Ziming Wang, Xiaolan Du, Min Jin, Chu-Xia Deng, Yangli Xie, Feng-Jin Guo, Liang Kuang, Di Chen
Publikováno v:
Annals of the Rheumatic Diseases. 79:112-122
ObjectivesThis study aims to investigate the role and mechanism of FGFR3 in macrophages and their biological effects on the pathology of arthritis.MethodsMice with conditional knockout of FGFR3 in myeloid cells (R3cKO) were generated. Gait behaviours
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5c29f9f189ab7d4938190a89ae072d
https://doi.org/10.1136/annrheumdis-2019-215696
https://doi.org/10.1136/annrheumdis-2019-215696
Publikováno v:
Histochemistry and cell biology. 154(2)
We previously report that BMP2 mediates mild ER stress-activated ATF6 and directly regulates XBP1S splicing in the course of chondrogenesis. The mammalian unfolded protein response (UPR) protects the cell against the stress of misfolded proteins in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47cba4f066f2dfbe0a65ea1bba24bc71
https://pubmed.ncbi.nlm.nih.gov/24934104
https://pubmed.ncbi.nlm.nih.gov/24934104
Publikováno v:
Genes & Diseases
Genes and Diseases, Vol 5, Iss 3, Pp 226-234 (2018)
Genes and Diseases, Vol 5, Iss 3, Pp 226-234 (2018)
Inflammation is indispensable for host defense, whereas excessive inflammation often develop inflammatory diseases. Autophagy is thought to be engaged in many extracellular stress responses, such as starvation and innate immunity. Thus, autophagy pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ea2556836da6d2e2a769d798c68a82
http://europepmc.org/articles/PMC6176218
http://europepmc.org/articles/PMC6176218
Publikováno v:
Histochemistry and Cell Biology. 156:191-191
The mammalian unfolded protein response (UPR) protects the cell against the stress of misfolded proteins in the endoplasmic reticulum (ER), and the transcription factor X-box binding protein 1 spliced (XBP1S), a regulator of the UPR, is known to be i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::668d521249445379e7f8dd1e4f60f867
https://doi.org/10.1007/s00418-021-02000-0
https://doi.org/10.1007/s00418-021-02000-0
Autor:
Chen Gong, Jian hua Wang, Hong Qiu, Feng‑Jin Guo, Ming‑Sheng Zhang, Hui hua Xiong, Teng‑Fei Chao, Yang Liu, Xiao Zhou, Liang Qin
Publikováno v:
International journal of molecular medicine. 46(6)
Osteosarcoma is the most common primary malignant tumor of the bone in adolescents and children, with high rates of metastasis and a poor prognosis. Recently, osteosarcoma cancer stem/stem‑like cells (CSCs) have been identified as the main cause of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5805d392b46c746ce9cc49e3a2cb4d13
https://pubmed.ncbi.nlm.nih.gov/33125116
https://pubmed.ncbi.nlm.nih.gov/33125116
Publikováno v:
Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-16 (2019)
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-16 (2019)
Background Autophagy and ER stress are involved in maintaining some well-orchestrated mechanisms aimed at either restoring cellular homeostasis or performing cell death. Autophagy is a well-defined process which governs overall cellular stress outcom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c9ad1c2055b4c574dce5f27aa9202f
https://pubmed.ncbi.nlm.nih.gov/31060556
https://pubmed.ncbi.nlm.nih.gov/31060556