Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Feng-Hua Lan"'
Autor:
Wen-jing Yang, Ai-zhen Yan, Yong-jun Xu, Xiao-yan Guo, Xian-guo Fu, Dan Li, Juan Liao, Duo Zhang, Feng-hua Lan
Publikováno v:
BMC Genetics, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background The disease gene of fragile X syndrome, FMR1 gene, encodes fragile X mental retardation protein (FMRP). The alternative splicing (AS) of FMR1 can affect the structure and function of FMRP. However, the biological functions of alte
Externí odkaz:
https://doaj.org/article/cdb14d04becc443eb8323dac6660e2ec
Publikováno v:
Biology of Reproduction. 106:108-117
Congenital absence of the vas deferens (CAVD), a congenital malformation of the male reproductive system, causes obstructive azoospermia and male infertility. Currently, the cystic fibrosis transmembrane conductance regulator (CFTR) has been recogniz
Autor:
Hui Zhang, Feng-Hua Lan, Guo-Yong Chen, Xiao-Yan Mei, Qing-Qin Li, Ying Tang, Zhi-Hong Wang, Li-Hong Dong, Duo Zhang, Wu-Jian Huang
Publikováno v:
Molecular Human Reproduction. 27
Acephalic spermatozoa syndrome (ASS) is a rare teratozoospermia that leads to male infertility. Previous work suggested a genetic origin. Variants of Sad1 and UNC84 domain containing 5 (SUN5) are the main genetic cause of ASS; however, its pathogenes
Autor:
Fenghua Lan, Wen-jing Yang, Juan Liao, Yong-jun Xu, Xiao-yan Guo, Xian-guo Fu, Dan Li, Ai-zhen Yan, Duo Zhang, Feng-hua Lan
The disease gene of fragile X syndrome, FMR1 gene, encodes fragile X mental retardation protein (FMRP). The alternative splicing of FMR1 can affect the structure and function of FMRP. However, the biological functions of alternatively spliced isoform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3317b4c393ef7aa02ce9b1e8ac89b985
https://doi.org/10.21203/rs.2.20949/v1
https://doi.org/10.21203/rs.2.20949/v1
Publikováno v:
Molecular Medicine Reports. 14:3785-3790
Dermatomyositis (DM) is a type of autoimmune inflammatory myopathy, which primarily affects the skin and muscle. The underlying mechanisms of DM remain poorly understood. The present study aimed to explore gene expression profile alterations, investi
Publikováno v:
Medical Journal of Chinese People's Liberation Army, Vol 41, Iss 2, Pp 168-174 (2016)
Spermatogonial stem cells (SSCs) have the ability of self-renewal and differentiate into sperm throughout the life of male animals. They are the unique adult stem cells that transmit genetic information to subsequent generations. Recently, accumulati
Autor:
Youliang Wang, Hui-Peng Chen, Duan Haifeng, Gao Lihua, Feng-Hua Lan, Hu Xianwen, Yong Shao, Duo Zhang, Keyan Chen
Publikováno v:
Journal of Cellular Biochemistry. 117:1649-1657
Ribosomal protein S6 (rpS6) has long been regarded as one of the primary r-proteins that functions in the early stage of 40S subunit assembly, but its actual role is still obscure. The correct forming of 18S rRNA is a key step in the nuclear synthesi
Autor:
Ai-zhen Yan, Wen-jing Yang, Duo Zhang, Juan Liao, Feng-hua Lan, Yong-jun Xu, Xian-guo Fu, De-zhu Zheng, Xiao-yan Guo
Publikováno v:
Gene. 731:144359
FMRP is an RNA-binding protein, loss of which causes fragile X syndrome (FXS). FMRP has several isoforms resulted from alternative splicing (AS) of fragile X mental retardation 1 (FMR1) gene, but their biological functions are still poorly understood
Publikováno v:
Zhonghua nan ke xue = National journal of andrology. 22(4)
Spermatogonial stem cells(SSCs) are a type of spermatogonial cells that play an important role in the spermatogenesis of males. SSCs not only possess the properties of stem cells but also differentiate into sperm. They are the unique adult stem cells
Autor:
De-zhu Zheng, Yuxiang Lin, Ai-zhen Yan, Duo Zhang, Feng-hua Lan, Qingqin Li, Juan Liao, Xian-guo Fu
Publikováno v:
Molecular Medicine Reports. 12:1957-1962
Fragile X mental retardation 1 gene (FMR1) expression is associated with fragile X syndrome (FXS) and exhibits several splicing products. However, the proportion of spliced isoforms that are expressed in different tissues remains unclear. In the pres